The Effect of GnRH on Pitutitary Hormones in Menstrual-Cycle Mood Related Disorders
NCT ID: NCT00001232
Last Updated: 2008-03-04
Study Results
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Basic Information
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COMPLETED
140 participants
OBSERVATIONAL
1988-07-31
2000-06-30
Brief Summary
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The purpose of this research study is to evaluate the hypothalamic-pituitary-gonadal axis activity as measured by pituitary hormones, FSH and LH in response to intravenous doses of gonadotropin releasing hormone (GnRH) in menstrual cycle-related hormones.
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Detailed Description
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Conditions
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Eligibility Criteria
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Inclusion Criteria
Female.
Use of barrier methods of birth control.
Not pregnant.
Not taking ongoing medications.
No medical illnesses.
FEMALE
Yes
Sponsors
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National Institute of Mental Health (NIMH)
NIH
Locations
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National Institute of Mental Health (NIMH)
Bethesda, Maryland, United States
Countries
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References
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Rubinow DR, Hoban MC, Grover GN, Galloway DS, Roy-Byrne P, Andersen R, Merriam GR. Changes in plasma hormones across the menstrual cycle in patients with menstrually related mood disorder and in control subjects. Am J Obstet Gynecol. 1988 Jan;158(1):5-11. doi: 10.1016/0002-9378(88)90765-x.
Schmidt PJ, Gindoff PR, Baron DA, Rubinow DR. Basal and stimulated gonadotropin levels in the perimenopause. Am J Obstet Gynecol. 1996 Sep;175(3 Pt 1):643-50. doi: 10.1053/ob.1996.v175.a74255.
Fujimoto VY, Klein NA, Battaglia DE, Bremner WJ, Soules MR. The anterior pituitary response to a gonadotropin-releasing hormone challenge test in normal older reproductive-age women. Fertil Steril. 1996 Mar;65(3):539-44.
Other Identifiers
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88-M-0132
Identifier Type: -
Identifier Source: secondary_id
880132
Identifier Type: -
Identifier Source: org_study_id
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