High-protein and High-carbohydrate Diets' Effect on Urinary Concentrating Ability

NCT ID: NCT00282321

Last Updated: 2010-02-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2007-05-31

Study Completion Date

2009-06-30

Brief Summary

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We wanted to test urinary concentrating ability and AQP-2 expression in kidney during high-protein and high-carbohydrate diet.

Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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High Protein diet

Intervention Type BEHAVIORAL

High carbohydrate diet

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* (1) Genders; both mal and female
* (2) Age; 18- 65 years old
* (3) BMI; below 30
* (4) Females had to bee in oral contraceptive treatment

Exclusion Criteria

* (1) Clinical signs or history of disease in the heart, lungs, kidneys or endocrine organs
* (2) Abnormal laboratory test (blood haemoglobin, white cell count, platelets, plasma sodium, plasma potassium, plasma creatinine, plasma albumin, plasma bilirubin, plasma alanine aminotransferase, plasma cholesterol and blood glucose)
* (3) Albuminuria or glucosuria
* (4) Cancer
* (5) Arterial hypertension
* (6) Alcohol abuse
* (7) Use of tobacco
* (8) Medical treatment, except oral contraceptives
* (9) Pregnancy or breast feeding
* (10) Medicine abuse
* (11) Donation of blood less than 1 month before the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Regional Hospital Holstebro

OTHER

Sponsor Role lead

Principal Investigators

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Erling B Pedersen, Professor

Role: STUDY_CHAIR

Holstebro Hospital, 7500 Holstebro Denmark

Thomas G Knudsen, MD

Role: PRINCIPAL_INVESTIGATOR

Holstebro Hospital, 7500 Holstebro, Denmark

Locations

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Department of Medicine, Holstebro Hospital

Holstebro, , Denmark

Site Status

Countries

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Denmark

Other Identifiers

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MED.RES.HOS.2006.01.TGK

Identifier Type: -

Identifier Source: org_study_id

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