Urinary Concentration and Diluting Ability in Patients With Chronic Renal Disease and/ or Hypertension

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-05-31

Brief Summary

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The investigators want to test the hypothesis that patients with chronic renal disease have a poorer ability to preserve water after being thirsty and a poorer ability to excrete water after a load of fluid. They presume that these abilities become poorer when renal insufficiency progresses. The investigators further hypothesize that patients with hypertension also have a decreased ability to concentrate and dilute urine.

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Detailed Description

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Conditions

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Renal Insufficiency, Chronic Hypertension

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Dialysis patients

No interventions assigned to this group

with or wthout glucose added to dialysis fluid

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with chronic renal insufficiency, aged between 18 and 65, both men and women
* Creatinine clearance between 30-59 ml/min
* Patients with hypertension, aged between 18 and 65, both men and women; hypertension is defined as a mean arterial blood pressure in the daytime that is more than 140/90 mm Hg.
* Healthy volunteers, aged between 18 and 65, both men and women