Natural Supplements for Unipolar Depression

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-12-31

Study Completion Date

2008-09-17

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study is being conducted to determine the clinical response rate for the regimen of L-methionine, betaine and folate for unipolar depression.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Potential Intervention Strategy With Folic Acid and Vitamin B12 in Patients With Schizophrenia

NCT02916121

Schizophrenia

UNKNOWN NA

Effect of Phosphatidylcholine on Plasma Homocysteine in Healthy Volunteers

NCT00102232

Healthy Cardiovascular Diseases

COMPLETED NA

Effect of Betaine, Serine and Folic Acid on Vascular Function in Healthy Volunteers

NCT00126347

Healthy Cardiovascular Diseases

COMPLETED NA

Methionine Tolerance in Healthy Human Adults

NCT02566434

Healthy

COMPLETED NA

Folate Augmentation of Treatment - Evaluation for Depression: a Randomised Controlled Trial

NCT00514410

Depression

COMPLETED PHASE4

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study is 6 weeks long, with 9 clinical visits. All visits will take place at our location in Massachusetts.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Unipolar Depression

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Supplements of L-methionine, betaine and folate

Group Type EXPERIMENTAL

Supplements of L-methionine, betaine and folate

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Supplements of L-methionine, betaine and folate

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* DSM-IV diagnosis of a MDD or DDNOS; clinical indication for treatment of current depressive symptoms; HDS \> 18; women of reproductive potential must use an acceptable method of birth control

Exclusion Criteria

* Treatment with another psychotropic drug; history of mania or hypomania; history of bipolar illness in first-degree relatives; active homicidality; pregnant; trying to become pregnant, or nursing; unstable medical condition; current substance abuse in the past month; history of sulfa allergy

Minimum Eligible Age

18 Years

Maximum Eligible Age

64 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes