Study of the Safety and Efficacy of Ferrlecit® Maintenance Dosing in Pediatric Hemodialysis Patients

NCT ID: NCT00224003

Last Updated: 2009-09-28

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

23 participants

Study Classification

INTERVENTIONAL

Study Start Date

2003-04-30

Study Completion Date

2005-02-28

Brief Summary

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A phase 4 clinical investigation in iron-replete pediatric hemodialysis patients, whose legal guardian had provided signed informed consent, and who had satisfied the inclusion and exclusion criteria of the study.

Detailed Description

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Conditions

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Anemia

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Sodium Ferric Gluconate Complex in Sucrose.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male or female pediatric ESRD, Patients \>\_ 2 and \<\_ 16 years of age, whose legally authorized representative provided signed informed consent.
* Stabilized on chronic hemodialysis therapy with an identified need for maintenance iron therapy.
* Predetermined TSAT and serum Ferritin (at the screening visit).
* Receiving a stable EPO dosing regimen.

Exclusion Criteria

* Receipt of any form of iron supplementation during the 2 weeks prior to the first Ferrlecit dosing.
* Hypersensitivity to Ferrlecit or any of its inactive components.
* High TSAT level.
* High Serum Ferritin
Minimum Eligible Age

2 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Watson Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Watson Laboratory, Inc

Principal Investigators

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Gary Hoel, RPh, PhD

Role: STUDY_DIRECTOR

Watson Laboratories, Inc.

Locations

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Birmingham, Alabama, United States

Site Status

Los Angeles, California, United States

Site Status

San Diego, California, United States

Site Status

Stanford, California, United States

Site Status

Atlanta, Georgia, United States

Site Status

Boston, Massachusetts, United States

Site Status

Kansas City, Missouri, United States

Site Status

The Bronx, New York, United States

Site Status

Dallas, Texas, United States

Site Status

Seattle, Washington, United States

Site Status

Countries

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United States

References

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Warady BA, Zobrist RH, Finan E; Ferrlecit Pediatric Study Group. Sodium ferric gluconate complex maintenance therapy in children on hemodialysis. Pediatr Nephrol. 2006 Apr;21(4):553-60. doi: 10.1007/s00467-006-0042-5. Epub 2006 Mar 7.

Reference Type RESULT
PMID: 16520948 (View on PubMed)

Other Identifiers

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FDA

Identifier Type: -

Identifier Source: secondary_id

FRO2001

Identifier Type: -

Identifier Source: org_study_id

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