The Use of Penile Vibratory Stimulation to Decrease Spasticity Following Spinal Cord Injury

NCT ID: NCT00223873

Last Updated: 2009-01-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2002-11-30

Study Completion Date

2006-07-31

Brief Summary

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The purpose of this study is to determine the effect of penile vibratory stimulation on the muscle spasticity of men with chronic spinal cord injury.

Detailed Description

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Spinal cord injury can result in mild to severe muscle spasms that can both inhibit functional capability and increase the likelihood of injury due to fall. Anecdotal reports and a recent study suggest that triggering the ejaculatory reflex in men with vibratory stimulation can result in a significant decrease in spasm activity over a period of 2 to 42 hours. This study examines the effects of penile vibratory stimulation on spasticity when conducted daily in the home setting.

Conditions

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Spinal Cord Injury Muscle Spasticity

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Interventions

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Penile Vibratory Stimulation

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Diagnosed with a traumatic spinal cord injury

* Level of injury is at T6 or below
* Injured at least 6 months prior to study enrollment
* Male, aged 18 to 70 years
* Spasticity to a degree that either anti-spasticity medications have been or are being used or current spasticity is at 2 or greater on the Ashworth scale specifically for the quadriceps muscle group (knee flexion)

Exclusion Criteria

* Medical instability
* Subjects may not use Cialis
* Use of Viagra, Levitra, Caverject, or vacuum constriction devices is restricted to no less than 8 hours prior to daily vibratory therapy
* Recent history of autonomic dysreflexia secondary to sexual stimulation
* Presence of intrathecal Baclofen pumps
* Inability or unwillingness to use the therapy daily
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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US Department of Veterans Affairs

FED

Sponsor Role lead

Principal Investigators

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Angelo E Gousse, MD

Role: PRINCIPAL_INVESTIGATOR

Miami VA Medical Center Urology Service

Locations

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Miami Veterans Affairs Medical Center

Miami, Florida, United States

Site Status

Countries

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United States

References

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Zierski J, Muller H, Dralle D, Wurdinger T. Implanted pump systems for treatment of spasticity. Acta Neurochir Suppl (Wien). 1988;43:94-9. doi: 10.1007/978-3-7091-8978-8_21.

Reference Type BACKGROUND
PMID: 3213666 (View on PubMed)

Maynard FM, Karunas RS, Waring WP 3rd. Epidemiology of spasticity following traumatic spinal cord injury. Arch Phys Med Rehabil. 1990 Jul;71(8):566-9.

Reference Type BACKGROUND
PMID: 2369291 (View on PubMed)

Young RR, Delwaide PJ. Drug therapy: spasticity (first of two parts). N Engl J Med. 1981 Jan 1;304(1):28-33. doi: 10.1056/NEJM198101013040107. No abstract available.

Reference Type BACKGROUND
PMID: 6448959 (View on PubMed)

Penn RD, Savoy SM, Corcos D, Latash M, Gottlieb G, Parke B, Kroin JS. Intrathecal baclofen for severe spinal spasticity. N Engl J Med. 1989 Jun 8;320(23):1517-21. doi: 10.1056/NEJM198906083202303.

Reference Type BACKGROUND
PMID: 2657424 (View on PubMed)

Knutsson E, Lindblom U, Martensson A. Plasma and cerebrospinal fluid levels of baclofen (Lioresal) at optimal therapeutic responses in spastic paresis. J Neurol Sci. 1974 Nov;23(3):473-84. doi: 10.1016/0022-510x(74)90163-4. No abstract available.

Reference Type BACKGROUND
PMID: 4154365 (View on PubMed)

Ochs G, Struppler A, Meyerson BA, Linderoth B, Gybels J, Gardner BP, Teddy P, Jamous A, Weinmann P. Intrathecal baclofen for long-term treatment of spasticity: a multi-centre study. J Neurol Neurosurg Psychiatry. 1989 Aug;52(8):933-9. doi: 10.1136/jnnp.52.8.933.

Reference Type BACKGROUND
PMID: 2487035 (View on PubMed)

Other Identifiers

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7927-09

Identifier Type: -

Identifier Source: org_study_id

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