Influence of Thoracic Epidural Anesthesia on Skin Sympathetic Activity and Heart Rate Variability

NCT ID: NCT00222391

Last Updated: 2009-01-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-04-30

Study Completion Date

2006-01-31

Brief Summary

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The purpose of the study is to evaluate the impact of epidural anesthesia on sympathetic activity in surgical patients. The study investigates whether a segmental sympathetic block can be determined and can be correlated to level of the sensoric blockade.

Detailed Description

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Conditions

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Abdominal Surgery Abdominothoracic Surgery

Study Design

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Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* elective surgery
* combined anesthesia with thoracic epidural anesthesia 8 (Th6-9
* Body-mass-index \< 30

Exclusion Criteria

* Fever, Hypothermia, SIRS
* Microangiopathy
* Neuropathy
* Sensomotoric deficits
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Muenster

OTHER

Sponsor Role lead

Principal Investigators

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Henrik Freise, MD

Role: PRINCIPAL_INVESTIGATOR

Department of Anesthesiology and Intensive Care, University Hospital Münster

Locations

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Department of Anesthesia and Intensive Care, University Hospital Muenster

Münster, , Germany

Site Status

Countries

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Germany

References

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Freise H, Meissner A, Lauer S, Ellger B, Radke R, Bruewer M, Brodner G, Van Aken HK, Sielenkamper AW, Fischer LG. Thoracic epidural analgesia with low concentration of bupivacaine induces thoracic and lumbar sympathetic block: a randomized, double-blind clinical trial. Anesthesiology. 2008 Dec;109(6):1107-12. doi: 10.1097/ALN.0b013e31818db16c.

Reference Type RESULT
PMID: 19034108 (View on PubMed)

Other Identifiers

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01-Anast-04

Identifier Type: -

Identifier Source: org_study_id

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