T Cell Response in Hypersensitivity Syndrome

NCT ID: NCT00213447

Last Updated: 2013-06-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2002-11-30

Study Completion Date

2005-12-31

Brief Summary

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immunological study of the T cell repertoire phenotype and functionality in hypersensitivity syndrome.

Detailed Description

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Conditions

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Hypersensitivity Syndrome

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* age \> 18
* cutaneous eruption
* lymph nodes
* hepatitis
* interstitial pneumonia
* nephritis
* cardiopathy
* eosinophilia
* hyperlymphocytosis

Exclusion Criteria

* age minor to 18
* HIV +
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Rouen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Pascal Joly, MD-PHD

Role: PRINCIPAL_INVESTIGATOR

UH rouen

Locations

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UH-Rouen

Rouen, , France

Site Status

Countries

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France

References

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Picard D, Janela B, Descamps V, D'Incan M, Courville P, Jacquot S, Rogez S, Mardivirin L, Moins-Teisserenc H, Toubert A, Benichou J, Joly P, Musette P. Drug reaction with eosinophilia and systemic symptoms (DRESS): a multiorgan antiviral T cell response. Sci Transl Med. 2010 Aug 25;2(46):46ra62. doi: 10.1126/scitranslmed.3001116.

Reference Type DERIVED
PMID: 20739682 (View on PubMed)

Other Identifiers

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2001/056/HP

Identifier Type: -

Identifier Source: org_study_id

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