Studies of the Immune Response in Normal Subjects and Patients With Disorders of the Immune System

NCT ID: NCT00001158

Last Updated: 2008-03-05

Basic Information

• Recruitment Status: COMPLETED
• Study Classification: OBSERVATIONAL
• Study Start Date: 1977-04-30
• Study Completion Date: 2000-03-31

Brief Summary

The goal of the protocol is to define the normal humoral and cellular immune responses to antigens in volunteers and to define abnormalities of these immune responses in patients with immunodeficiency diseases or cancer. In vitro assays and in vivo skin tests and immunization with antigens will be utilized.

Detailed Description

The goal of the protocol is to define the normal humoral and cellular immune responses to antigens in volunteers and to define abnormalities of these immune responses in patients with immunodeficiency diseases or cancer. In vitro assays and in vivo skin tests and immunization with antigens will be utilized.

Conditions

Immunologic Deficiency Syndromes; Neoplasms

Eligibility Criteria

Inclusion Criteria

Patients will be studied if a disorder of the immune system is suspected.

• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

National Cancer Institute (NCI)

NIH

Sponsor Role: lead

Locations

National Cancer Institute (NCI)

Bethesda, Maryland, United States

Countries

United States

References

Nelson DL, Blaese RM, Strober W, Bruce R, Waldmann TA. Constrictive pericarditis, intestinal lymphangiectasia, and reversible immunologic deficiency. J Pediatr. 1975 Apr;86(4):548-54. doi: 10.1016/s0022-3476(75)80145-4.

Reference Type: BACKGROUND

PMID: 1127501 (View on PubMed)

Other Identifiers

77-C-0066

Identifier Type: -

Identifier Source: secondary_id

770066

Identifier Type: -

Identifier Source: org_study_id