Study of the Anti-tumoral Immune Response

NCT ID: NCT02854644

Last Updated: 2022-06-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

167 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-27

Study Completion Date

2021-10-27

Brief Summary

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This study evaluates the frequency of the spontaneous T cells specific CD4 answers of tumoral antigens breast cancer and glioma.

Detailed Description

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Conditions

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Breast Cancer Glioma

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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glioma

1 additional blood sample for patients with glioma and without treatment

Group Type EXPERIMENTAL

additional blood sample

Intervention Type OTHER

breast cancer

2 additional blood samples for patients with localized brest cancer, metastatic breast cancer in 1st line of treatment and breast cancer in second line of treatment.

Group Type EXPERIMENTAL

additional blood sample

Intervention Type OTHER

breast cancer HER2+

1 additional blood sample for patients with metastatic breast cancer with HER2 surexpression

Group Type EXPERIMENTAL

additional blood sample

Intervention Type OTHER

Breast Cancer HER 2+ or HER2 triple -

1 additional blood sample for patients with breast cancer HER2 + or HER2 triple negative treated by neo adjuvant

Group Type EXPERIMENTAL

additional blood sample

Intervention Type OTHER

Interventions

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additional blood sample

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Performance status 0,1 or 2
* breast cancer or glioma
* Arm glioma: patients without anti-tumoral treatment
* Arm breast cancer: inclusion before treatment
* Arm breast cancer HER2: patients with current therapy

Exclusion Criteria

* Psychiatric disease compromising the understanding of the information or the realization of the study
* vulnerable People according to the law (minors, adults under protection, private persons of freedom ...)
* Unaffiliated People to the Social Security
* People being for the period of exclusion from another study
* Life expectancy estimated unless 3 months.
* For patients in Arm glioma: patients having already begun a systematic treatment.
* For patients with a breast cancer: patient already under current therapy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Centre Hospitalier Régional Universitaire

Besançon, , France

Site Status

Countries

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France

Other Identifiers

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P/2013/188

Identifier Type: -

Identifier Source: org_study_id

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