Immune Repertoire of Ovarian HGSC

NCT ID: NCT03794115

Last Updated: 2019-01-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-01-03

Study Completion Date

2022-01-01

Brief Summary

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In this preliminary study, peripheral blood and carcinoma tissue with pericarcinomatous tissue are taken from the patients with ovarian high grade serous carcinoma at several points: before any treatment, after the debulking surgery, and after all the proposed chemotherapy. The differential expression of the T/B lymphocyte receptors in these samples will be analyzed with the platinum-based treatment and survival outcomes of the patients. The primary objective is the expression rates of T/B lymphocyte receptors in different stages of checking points.

Detailed Description

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Conditions

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Ovarian High Grade Serous Carcinoma Immune Repertoire T Lymphocyte Receptor B Lymphocyte Receptor

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Treatment for ovarian cancer

The treatment for ovarian cancer includes the debulking surgery and platinum-based chemotherapy.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Confirmed of primary ovarian high grade serous carcinoma
* Aged 18 years or older
* No immunosuppressive disease
* Signed an approved informed consents
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Lei Li

OTHER

Sponsor Role lead

Responsible Party

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Lei Li

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Lei Li

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Lei Li, M.D.

Role: CONTACT

+8613911988831

Facility Contacts

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Lei Li, MD

Role: primary

008613911988831

Other Identifiers

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EOC-IMMUNE

Identifier Type: -

Identifier Source: org_study_id

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