Cervix:Hypoxia, Interstitial Fluid Pressure and GSH Levels

NCT ID: NCT00188539

Last Updated: 2025-02-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

PHASE2

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

1995-12-31

Study Completion Date

2027-12-31

Brief Summary

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The aim of this study is to measure the oxygen content and interstitial fluid pressure in cervix cancer patients. Tumour oxygen content and internal pressure of tumours may be an important factor that influences the effectiveness of radiotherapy and other treatments.

Detailed Description

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Conditions

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Cervix Neoplasms

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Pre-treatment tumour oxygen measurements (under anesthesia)

Group Type EXPERIMENTAL

Pre-treatment tumour oxygen measurements (under anesthesia)

Intervention Type PROCEDURE

Interventions

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Pre-treatment tumour oxygen measurements (under anesthesia)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Newly diagnosed patients with carcinoma of the cervix ( 3 cm in size or larger) where an examination under anesthesia is to be performed for staging purposes
* Informed consent

Exclusion Criteria

* Patients with clinically occult cervix carcinoma
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Canadian Cancer Trials Group

NETWORK

Sponsor Role collaborator

Princess Margaret Hospital, Canada

OTHER

Sponsor Role collaborator

University Health Network, Toronto

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Anthony Fyles, MD

Role: PRINCIPAL_INVESTIGATOR

Princess Margaret Hospital, Canada

Locations

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Princess Margaret Hospital

Toronto, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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National Cancer Inst of Canada

Identifier Type: -

Identifier Source: secondary_id

UHN REB 01-0376-C

Identifier Type: -

Identifier Source: org_study_id

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