Effect of Increased Oxygenation in the Air During Endurance Training in Stable Angina Pectoris Patients

NCT ID: NCT00184444

Last Updated: 2016-07-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

25 participants

Study Classification

INTERVENTIONAL

Study Start Date

2004-09-30

Study Completion Date

2007-07-31

Brief Summary

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The study investigates whether endurance training breathing 100% oxygen gives a additional improvement of maximal oxygen uptake in stable Angina Pectoris patients, compared to training without extra oxygen supplementation. In addition work economy, stroke volume and cardiac perfusion is measured.

The hypothesis of the study is that increased oxygenation of the air increases performance, stroke volume, work economy and cardiac perfusion.

Detailed Description

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Conditions

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Angina Pectoris

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Hypoxic Interval training

4 x 4 minutes interval training with 100% oxygenated air

Group Type EXPERIMENTAL

Hypoxic interval training

Intervention Type BEHAVIORAL

4 x 4 minutes interval training in hypoxic air, 3 times per week at 90-95% HR max

Normoxic interval training

4 x 4 minutes interval training in normoxic air

Group Type EXPERIMENTAL

Normoxic interval training

Intervention Type BEHAVIORAL

4 x 4 minutes normoxic interval training, 3 times per week at 90-95% HR max

Interventions

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Hypoxic interval training

4 x 4 minutes interval training in hypoxic air, 3 times per week at 90-95% HR max

Intervention Type BEHAVIORAL

Normoxic interval training

4 x 4 minutes normoxic interval training, 3 times per week at 90-95% HR max

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* stable angina pectoris age 18-75

Exclusion Criteria

* unstable angina pectoris
* Limitations to exercise other than coronary artery disease
* Participants in other study interventions
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aarhus University Hospital

OTHER

Sponsor Role collaborator

Norwegian University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Asbjørn Støylen, MD

Role: STUDY_DIRECTOR

Norwegian university of sience and technology

Locations

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Norwegian University of Science and Technology

Trondheim, , Norway

Site Status

Countries

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Norway

References

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Karlsen T, Hoff J, Stoylen A, Skovholdt MC, Gulbrandsen Aarhus K, Helgerud J. Aerobic interval training improves VO2 peak in coronary artery disease patients; no additional effect from hyperoxia. Scand Cardiovasc J. 2008 Oct;42(5):303-9. doi: 10.1080/14017430802032723.

Reference Type RESULT
PMID: 18609057 (View on PubMed)

Other Identifiers

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094-2004

Identifier Type: -

Identifier Source: org_study_id

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