Comparison of Different Mucoactive Agents for the Care of the Intubated Patient in a Surgical Trauma Intensive Care Unit

NCT ID: NCT00131521

Last Updated: 2009-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

260 participants

Study Classification

INTERVENTIONAL

Study Start Date

2005-01-31

Study Completion Date

2007-12-31

Brief Summary

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This study compares N-acetylcysteine (mucomyst) and sodium chloride to determine their efficacy in the prevention of pulmonary mucus obstruction and retention in intubated patients admitted to the surgical trauma intensive care unit (STICU).

Detailed Description

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Conditions

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Mucus Obstruction Intubation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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mucomyst

Intervention Type DRUG

sodium chloride (saline)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Intubated and admitted to the Surgical Trauma Intensive Care Unit (STICU)
* Subjects must be eligible to start treatment within 24 hours of their initial intubation

Exclusion Criteria

* Patient anticipated to be extubated within 24 hours following STICU admission
* Hypersensitivity to acetylcysteine.
* Pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The University of Texas Health Science Center at San Antonio

OTHER

Sponsor Role lead

Principal Investigators

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John G. Myers, M.D.

Role: PRINCIPAL_INVESTIGATOR

University of Texas Health Science Center San Antonio

Locations

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Univesity Hospital

San Antonio, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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034-1502-320

Identifier Type: -

Identifier Source: org_study_id

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