Intravenous Tedisamil in the Rapid Conversion of Atrial Fibrillation or Flutter to Normal Sinus Rhythm in Female Subjects

NCT ID: NCT00126074

Last Updated: 2015-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Study Classification

INTERVENTIONAL

Study Start Date

2004-10-31

Study Completion Date

2006-03-31

Brief Summary

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The purpose of this study is to demonstrate the ability of tedisamil to convert atrial fibrillation or flutter into normal sinus rhythm (NSR) in female patients.

Detailed Description

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Conditions

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Atrial Fibrillation Atrial Flutter

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Interventions

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Tedisamil sesquifumarate

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Willing to sign informed consent before screening examinations are performed and before the study drug is administered
* Females \> 18 years of age
* Subjects with documented (60 second rhythm strip) symptomatic atrial fibrillation or flutter (duration \> 3 hours and \< 45 days) at the time of randomization
* Subjects who are in no distress and hemodynamically stable (supine systolic blood pressure \> 90 mmHg and diastolic blood pressure \< 105 mmHg)

Exclusion Criteria

* Pregnancy and lactation
* Acute myocardial infarction and cerebrovascular accidents
* Coronary syndromes and congestive heart failure (CHF) New York Heart Association (NYHA) IV
* Life-threatening ventricular arrhythmias and electrocardiogram (ECG) abnormalities
* Concurrent antiarrhythmic treatments
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Solvay Pharmaceuticals

INDUSTRY

Sponsor Role lead

Principal Investigators

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Global Clinical Director Solvay

Role: STUDY_DIRECTOR

Solvay Pharmaceuticals

Locations

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Site 26

Honolulu, Hawaii, United States

Site Status

Site 27

Tullahoma, Tennessee, United States

Site Status

Site 5

Pleven, , Bulgaria

Site Status

Site 2

Sofia, , Bulgaria

Site Status

Site 3

Sofia, , Bulgaria

Site Status

Site 4

Sofia, , Bulgaria

Site Status

Site 6

Sofia, , Bulgaria

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Site 7

Sofia, , Bulgaria

Site Status

Site 8

Mannheim, , Germany

Site Status

Site 11

Budapest, , Hungary

Site Status

Site 12

Budapest, , Hungary

Site Status

Site 14

Budapest, , Hungary

Site Status

Site 15

Budapest, , Hungary

Site Status

Site 9

Budapest, , Hungary

Site Status

Site 13

Kecskemét, , Hungary

Site Status

Site 10

Korhaz, , Hungary

Site Status

Site 16

Piacenza, , Italy

Site Status

Site 22

Chrzanów, , Poland

Site Status

Site 20

Gdansk, , Poland

Site Status

Site 25

Gdynia, , Poland

Site Status

Site 19

Katowice, , Poland

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Site 18

Krakow, , Poland

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Site 24

Szczecin, , Poland

Site Status

Site 17

Tarnów, , Poland

Site Status

Site 23

Wałbrzych, , Poland

Site Status

Site 21

Zakopane, , Poland

Site Status

Countries

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United States Bulgaria Germany Hungary Italy Poland

Other Identifiers

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2004-000346-21

Identifier Type: -

Identifier Source: secondary_id

S219.3.118

Identifier Type: -

Identifier Source: org_study_id

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