Effects of Neighborhood SES on Coronary Heart Disease Burden in Communities - Ancillary to ARIC
NCT ID: NCT00106951
Last Updated: 2012-01-31
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
12000 participants
OBSERVATIONAL
2005-04-30
2009-03-31
Brief Summary
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Detailed Description
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Despite strong decreases in coronary heart disease (CHD) mortality over past decades, there is evidence that racial and socioeconomic disparities in CHD mortality are increasing. CHD surveillance efforts that examine trends within these population subgroups are an important first step in quantifying and reducing disparities. The Atherosclerosis Risk in Communities (ARIC) Study has monitored rates and trends in validated hospitalized myocardial infarction and fatal CHD among black and white adults aged 35 to 74 years in four U.S. communities since 1989.
DESIGN NARRATIVE:
The study will expand the scope of ARIC surveillance by examining variations in the rates and temporal trends in CHD by socioeconomic status (SES), measured at the level of census tract. For CHD events already included in ARIC surveillance (1992-2002), addresses will be obtained from medical records and death certificates and geocoded so that they can be matched with identifiers for census based geographical areas. The ARIC study will contribute yearly updates of abstracted CHD events and addresses for subsequent years (2003-2005). Each event will be linked with census tract level SES indicators available from the 1990 and 2000 censuses. This novel effort will permit an examination of disparities by SES in rates and trends in fatal CHD, hospitalized myocardial infarction, case fatality, use of invasive cardiac procedures and prescription of efficacious medication at time of hospital discharge. In addition, the extent to which racial disparities in CHD and associated treatments are explained by SES will also be explored.
Conditions
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Study Design
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RETROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
35 Years
74 Years
ALL
No
Sponsors
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National Heart, Lung, and Blood Institute (NHLBI)
NIH
University of North Carolina, Chapel Hill
OTHER
Responsible Party
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Kathryn Rose
Adjunct Associate Professor
Principal Investigators
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Kathryn M Rose, PhD
Role: PRINCIPAL_INVESTIGATOR
UNC (Adjunct)
References
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Foraker RE, Rose KM, Kucharska-Newton AM, Ni H, Suchindran CM, Whitsel EA. Variation in rates of fatal coronary heart disease by neighborhood socioeconomic status: the atherosclerosis risk in communities surveillance (1992-2002). Ann Epidemiol. 2011 Aug;21(8):580-8. doi: 10.1016/j.annepidem.2011.03.004. Epub 2011 Apr 23.
Foraker RE, Rose KM, Whitsel EA, Suchindran CM, Wood JL, Rosamond WD. Neighborhood socioeconomic status, Medicaid coverage and medical management of myocardial infarction: atherosclerosis risk in communities (ARIC) community surveillance. BMC Public Health. 2010 Oct 21;10:632. doi: 10.1186/1471-2458-10-632.
Rose KM, Suchindran CM, Foraker RE, Whitsel EA, Rosamond WD, Heiss G, Wood JL. Neighborhood disparities in incident hospitalized myocardial infarction in four U.S. communities: the ARIC surveillance study. Ann Epidemiol. 2009 Dec;19(12):867-74. doi: 10.1016/j.annepidem.2009.07.092. Epub 2009 Oct 7.
Foraker RE, Rose KM, McGinn AP, Suchindran CM, Goff DC Jr, Whitsel EA, Wood JL, Rosamond WD. Neighborhood income, health insurance, and prehospital delay for myocardial infarction: the atherosclerosis risk in communities study. Arch Intern Med. 2008 Sep 22;168(17):1874-9. doi: 10.1001/archinte.168.17.1874.
Other Identifiers
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1292
Identifier Type: -
Identifier Source: org_study_id
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