Cardiovascular Disease Knowledge/Morbidity--Socioeconomic Cohort Outcomes

NCT ID: NCT00005480

Last Updated: 2016-02-18

Basic Information

• Recruitment Status: COMPLETED
• Study Classification: OBSERVATIONAL
• Study Start Date: 1996-09-30
• Study Completion Date: 1998-08-31

Brief Summary

To elucidate the interrelationship of level of cardiovascular disease knowledge and subsequent clinical health status by merging population-based cardiovascular disease risk factor survey data with patient-level hospital data. The overall goal was to assess outcomes in the positive/negative association between level of cardiovascular disease knowledge and incidence and relative degree of morbidity among a cohort with and without major cardiovascular disease risk factors.

Detailed Description

BACKGROUND:

Evidence shows a growing disparity in the prevalence of modifiable risk factors and incidence of cardiovascular disease between upper and lower socioeconomic status (SES) individuals. Trends in knowledge about risk factors and risk reduction strategies parallel these findings. Research determining the differential association between level of cardiovascular disease knowledge and subsequent clinical health status had not been conducted.

DESIGN NARRATIVE:

Analyses were stratified according to SES (via years of formal education), controlling for age, gender, and ethnicity (Latino/Anglo). Sociodemographic, physiologic, and knowledge measurements were available on each participant. Morbidity estimates and clinical health status indicators were available via primary and secondary discharge diagnostic codes from public-use hospital discharge databases collected on all California hospital admissions for the entire study period. The Stanford Five City Program data were merged with the hospital discharge data, matching on survey participant's social security number which was subsequently converted to a unique personal identifier. Baseline 1989/90 and 1991 through 1995 longitudinal outcomes were assessed.

There were three main aims, all of which had epidemiologic and cardiovascular disease health policy prevention implications: Aim 1: Characterize the distribution of hospitalized versus non-hospitalized SES sub-cohorts according to level of C.D. knowledge, physiologic risk factor prevalence, and clinical morbidity prevalence. Aim 2: Test the hypothesis that morbidity differences between hospitalized SES sub-cohorts would vary as a function of baseline level of cardiovascular disease knowledge and risk factor prevalence. Aim 3: Test the hypothesis that morbidity would rise among hospitalized lower SES sub-cohorts, resulting in widening health status disparities by the end of the study period. Parametric and nonparametric analytic methods were used, including analysis of variance and covariance, and various regression techniques.

The study completion date listed in this record was obtained from the "End Date" entered in the Protocol Registration and Results System (PRS) record.

Conditions

Cardiovascular Diseases; Heart Diseases

Eligibility Criteria

• Maximum Eligible Age: 100 Years
• Eligible Sex: MALE
• Accepts Healthy Volunteers: No

Sponsors

National Heart, Lung, and Blood Institute (NHLBI)

NIH

Sponsor Role: lead

Other Identifiers

R03HL057578

Identifier Type: NIH

Identifier Source: secondary_id

View Link

4964

Identifier Type: -

Identifier Source: org_study_id