The Connection Between Areas in the Brain of Blind Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

1999-04-30

Study Completion Date

2003-11-30

Brief Summary

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The purpose of this study is to test the belief that specific areas of the brain are connected differently in blind patients than patients with sight. In addition, the study will examine the different anatomical connections between brain areas of patients who became blind early in life versus patients who became blind later.

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Detailed Description

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The purpose of this protocol is to test the hypothesis that the anatomical connectivity of occipital and somatosensory areas in early blind subjects differs from that in subjects who became blind later in life and from that in sighted volunteers.

Conditions

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Blindness Brain Mapping Healthy

Interventions

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O15

Intervention Type DRUG

Cadwell rTMS

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

Subjects with late blindness.

Subjects with early blindness.

Sighted volunteers.

Age between 18 and 65 years.

Exclusion Criteria

Subjects with personal or family history of seizures or other neurological or demyelinating disorders.

Pregnant women tested after urine pregnancy test.

Subjects with metal in the cranium except mouth.

Subjects with intracardiac lines and implanted medication pumps.

Subjects with increased intracranial pressure as evaluated by clinical means.

Subjects with cardiac pacemakers.

Intake or neuroleptics.

Subjects with blindness secondary to degenerative CNS diseases.

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes