Clinical Trials Updated in 2025

NCT06681220 | NOT_YET_RECRUITING | PHASE1/PHASE2

166 Participants

Biomarker Directed Trial of Temozolomide and Stenoparib in Relapsed SCLC

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2026-01-12

Completion: 2029-12-31

Conditions

Relapsed Small Cell Lung Cancer Recurrent Small Cell Lung Cancer

Interventions

COMBINATION_PRODUCT DRUG

No Results Yet

NCT06680479 | SUSPENDED | PHASE1

30 Participants

Safety and Immunogenicity of Stabilized CH505 TF chTrimer Vaccination in Adults Living With HIV-1 on Suppressive Antiretroviral Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2025-04-01

Completion: 2027-04-30

Conditions

HIV-1

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT06680089 | RECRUITING | PHASE2

300 Participants

CD70-targeted immunoPET Imaging of Kidney Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-11-27

Completion: 2026-11-30

Conditions

Urologic Neoplasms Urogenital Neoplasms Kidney Neoplasms Neoplasms

Interventions

DRUG

No Results Yet

NCT06675955 | RECRUITING | PHASE3

500 Participants

An Extension Study to Assess Impact of Multiple Sclerosis (MS) on Physical Function and Provide Continued Ocrelizumab Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-12-13

Completion: 2029-12-31

Conditions

Multiple Sclerosis

Interventions

DRUG

No Results Yet

NCT06649682 | SUSPENDED | PHASE1

20 Participants

68Ga-NYM096/177Lu-NYM096 in Metastatic ccRCC

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-11-21

Completion: 2026-10-31

Conditions

Clear Cell Renal Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT06625047 | COMPLETED | PHASE4

30 Participants

Comparing Telehealth and In-person Assessments in Glioma Patients Receiving Oral Chemotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-07

Completion: 2025-11-12

Conditions

Astrocytoma, IDH-Mutant Glioblastoma Glioma Oligodendroglioma, IDH-Mutant and 1p/19q-Codeleted

Interventions

BEHAVIORAL OTHER DRUG

No Results Yet

NCT06600802 | RECRUITING | NA

120 Participants

Intrinsic Validity of Molecular Marker(s) Detection on Tissular Tumoral DNA to Predict the Efficacy of 177Lutetium-PSMA-617 (Lu-PSMA) Treatment for Castration-resistant Metastatic Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-08

Completion: 2034-06-30

Conditions

Castration-resistant Metastatic Prostate Cancer Treated by 177Lutetium-PSMA-617 (Lu-PSMA)

Interventions

BIOLOGICAL

No Results Yet

NCT06597747 | COMPLETED | NA

20 Participants

Design Improvements With SONNET 3

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-12-16

Completion: 2025-05-22

Conditions

Hearing Loss, Sensorineural

Interventions

DEVICE

Results Available

NCT06576024 | COMPLETED | PHASE4

392 Participants

Immunogenicity and Safety of Inactivated Hepatitis A Vaccine in HIV-infected People

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2023-12-19

Completion: 2025-04-25

Conditions

Hepatitis A Immunodeficiency HIV Infections

Interventions

BIOLOGICAL

No Results Yet

NCT06571448 | ACTIVE_NOT_RECRUITING | PHASE2

138 Participants

Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-09-16

Completion: 2026-01-31

Conditions

Trigeminal Neuralgia

Interventions

DRUG

No Results Yet

NCT06568718 | COMPLETED | NA

229 Participants

Efficacy and Safety of Longidaze in the Treatment of Lower Urinary Tract Symptoms Associated With Benign Prostatic Hyperplasia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2023-03-20

Completion: 2024-02-09

Conditions

Lower Urinary Tract Symptoms Prostatic Hyperplasia

Interventions

DRUG

No Results Yet

NCT06568094 | RECRUITING | PHASE1/PHASE2

100 Participants

A Study of HRS-5041 Tablets Combined With Antitumor Therapy in Subjects With Advanced Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-09-25

Completion: 2026-06-30

Conditions

Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06567704 | RECRUITING

20 Participants

Cancer-related Fatigue During Maintenance Immunotherapy for Non-small Cell Lung Cancer (NSCLC): a Qualitative Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-31

Start Date: 2025-03-26

Completion: 2026-08-30

Conditions

Non-small Cell Lung Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT06567041 | COMPLETED | PHASE1

82 Participants

A Research Study of How Safe a New Medicine Called NNC0519 0130 is and to Test Its Effect in People Living With Excess Body Weight With or Without Type 2 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-08-07

Completion: 2025-12-10

Conditions

Diabetes Mellitus, Type 2 Obesity

Interventions

DRUG

No Results Yet

NCT06566690 | RECRUITING

56 Participants

The Association Between Sensory Block Level, Oxygen Therapy, and ORi in Varicose Vein Patients Undergoing Spinal Anesthesia (ORi: Oxygen Reserve Index)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-31

Start Date: 2024-08-29

Completion: 2026-01-22

Conditions

Hyperoxia Hypoxia

Interventions

DEVICE

No Results Yet

NCT06559891 | RECRUITING | NA

261 Participants

THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-03

Completion: 2026-02-28

Conditions

Hypertension

Interventions

DEVICE OTHER

No Results Yet

NCT06539338 | RECRUITING | PHASE1

34 Participants

A Study to Investigate Safety of INT2104 Infusions in Participants Aged 18 Years of Age and Older Who Have B-cell Cancers That Came Back After Previous Treatment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-07

Completion: 2028-03-31

Conditions

Lymphomas Non-Hodgkin's B-Cell Precursor Cell Lymphoblastic Leukemia-Lymphoma

Interventions

GENETIC

No Results Yet

NCT06531499 | RECRUITING | PHASE1

106 Participants

A Study of Radiation Dosimetry, Safety, and Tolerability of Extended Lutetium (177Lu) Vipivotide Tetraxetan Treatment in Chemo-naïve Adults With Metastatic Castration-resistant Prostate Cancer: RADIOpharmaceutical DOSimetry Evaluation (RADIODOSE) Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-11-11

Completion: 2028-11-24

Conditions

Metastatic Castration-Resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT06524427 | RECRUITING | NA

1124 Participants

Robot-Assisted vs. Video-Assisted Lobectomy for NSCLC (RAVAR)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2020-08-25

Completion: 2030-12-31

Conditions

Non Small Cell Lung Cancer

Interventions

PROCEDURE

No Results Yet

NCT06516965 | RECRUITING | PHASE3

330 Participants

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-10

Completion: 2026-10-19

Conditions

Prurigo Nodularis

Interventions

DRUG

No Results Yet

NCT06512558 | RECRUITING | NA

20 Participants

Augmented Reality Feasibility for Non-invasive Preoperative Tracking in Breast Cancer Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-11-14

Completion: 2027-11-01

Conditions

Subclinical Breast Cancer Lesion

Interventions

PROCEDURE

No Results Yet

NCT06506773 | COMPLETED

Study Type: OBSERVATIONAL

Last Updated: 2025-12-31

Start Date: 2024-10-14

Completion: 2032-07-15

Conditions

Primary Biliary Cholangitis

No Results Yet

NCT06440967 | RECRUITING | PHASE3

540 Participants

A Study to Confirm if Fezolinetant Helps Reduce Hot Flashes in Women With Breast Cancer Who Are Having Hormone Therapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-07-31

Completion: 2026-08-31

Conditions

Hot Flashes

Interventions

DRUG

No Results Yet

NCT06420245 | RECRUITING | NA

240 Participants

Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2025-12-31

Completion: 2026-11-30

Conditions

Diabetic Foot Ulcer

Interventions

DEVICE PROCEDURE

No Results Yet

NCT06415773 | COMPLETED | PHASE3

367 Participants

Effects of Berberine Ursodeoxycholate (HTD1801) Versus Dapagliflozin in Patients With Type 2 Diabetes Inadequately Controlled With Metformin

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-06-04

Completion: 2025-06-13

Conditions

T2DM (Type 2 Diabetes Mellitus)

Interventions

DRUG

No Results Yet

NCT06411158 | RECRUITING | NA

216 Participants

Training for Urinary Leakage Improvement After Pregnancy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-11-12

Completion: 2027-05-12

Conditions

Urinary Incontinence Delivery Complication

Interventions

OTHER DEVICE

No Results Yet

NCT06392464 | COMPLETED

106 Participants

Validation of Naevia Medical in Valvulopathies

Study Type: OBSERVATIONAL

Last Updated: 2025-12-31

Start Date: 2024-03-27

Completion: 2025-01-24

Conditions

Heart Valve Disease

Interventions

DEVICE

Results Available

NCT06389539 | RECRUITING | NA

220 Participants

Synbiotic to Attenuate Resorption of the Skeleton

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-08-12

Completion: 2028-04-30

Conditions

Osteoporosis Inflammation Aging

Interventions

OTHER

No Results Yet

NCT06366789 | RECRUITING | PHASE1

150 Participants

Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-05-29

Completion: 2026-01-31

Conditions

AML With Gene Mutations

Interventions

DRUG

No Results Yet

NCT06362005 | COMPLETED | PHASE4

50 Participants

The Efficacy of Selenium as an Alternative or Complementary Topical Treatment of Oral Lichen Planus

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-05-01

Completion: 2025-07-01

Conditions

Lichen Planus, Oral

Interventions

DRUG

No Results Yet

NCT06359808 | RECRUITING

Study Type: INTERVENTIONAL

Last Updated: 2025-12-31

Start Date: 2024-05-29

Completion: 2027-12-30

Conditions

CLDN18.2-positive Advanced Solid Tumor

Interventions

DRUG

No Results Yet