Clinical Trials
Showing trials with last updates posted in 2025.
500
Participants
Rod and Cone Mediated Function in Retinal Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2016-03-24
Completion:
2029-12-30
Conditions
Retinal Degeneration
Retinitis Pigmentosa
Stargardt's Disease
No Results Yet
148
Participants
High Image Matrix CT Reconstruction
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2015-11-09
Completion:
2020-03-27
Conditions
Healthy Subjects
Pulmonary-Related Conditions
Cardiac-Related Conditions
No Results Yet
40
Participants
Investigation of Blood-Brain-Barrier Breakdown Using Manganese Magnetic Resonance Imaging in Drug-Resistant Epilepsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2024-11-19
Completion:
2026-07-01
Conditions
Epilepsy
Interventions
DRUG
No Results Yet
877
Participants
An Extension Study of RPC1063 as Therapy for Moderate to Severe Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2015-12-02
Completion:
2024-12-19
Conditions
Ulcerative Colitis
Interventions
DRUG
10
Participants
Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2015-01-31
Completion:
2019-06-30
Conditions
Acute Pain
Chronic Pain
Hernia
Anesthesia, Intravenous
Anesthesia, Intratracheal
Interventions
DRUG
30
Participants
Periganglionic Resiniferatoxin for the Treatment of Intractable Pain Due to Cancer-induced Bone Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2025-12-19
Completion:
2026-12-01
Conditions
Intractable Pain
Palliative Care
Interventions
DRUG
No Results Yet
53
Participants
Dynamic Post-Prandial Metabolism in Patients With Non-Alcoholic Fatty Liver Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2015-10-28
Completion:
2020-05-14
Conditions
Liver Disease
Fatty Liver
No Results Yet
54
Participants
Phase I Trial of TURALIO(R) (Pexidartinib, PLX3397) in Children and Young Adults With Refractory Leukemias and Refractory Solid Tumors Including Neurofibromatosis Type 1 (NF1) Associated Plexiform Neurofibromas (PN) and Tenosynovial Giant Cell Tumor ...
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2015-04-29
Completion:
2026-12-31
Conditions
Neurofibroma, Plexiform
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Leukemia, Promyelocytic, Acute
Sarcoma
Interventions
DRUG
No Results Yet
172
Participants
A Study to Learn About the Effects and Safety of RTA 408 (Omaveloxolone) in People Aged 16 to 40 With Friedreich's Ataxia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2015-01-31
Completion:
2019-10-31
Conditions
Friedreich Ataxia
Interventions
DRUG
159
Participants
mTORC1/2 Inhibitor AZD2014 or the Oral AKT Inhibitor AZD5363 for Recurrent Endometrial and Ovarian
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2014-11-11
Completion:
2026-06-30
Conditions
BRCA1 Mutation Carrier
BRCA2 Mutation Carrier
Endometrial Adenocarcinoma
Estrogen Receptor Negative
HER2/Neu Negative
High Grade Ovarian Serous Adenocarcinoma
Progesterone Receptor Negative
Recurrent Breast Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Ovarian Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Uterine Corpus Carcinoma
Stage III Uterine Corpus Cancer AJCC v7
Stage IV Breast Cancer AJCC v6 and v7
Stage IV Uterine Corpus Cancer AJCC v7
Triple-Negative Breast Carcinoma
Interventions
DRUG
OTHER
No Results Yet
272
Participants
Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults With Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2014-04-03
Completion:
2023-08-16
Conditions
HIV
Cancer
Chronic Granulomatous Disease
Dock 8 Deficiency
No Results Yet
200
Participants
Clinical and Basic Investigations Into Known and Suspected Congenital Disorders of Glycosylation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2014-03-07
Completion:
2030-12-01
Conditions
Congenital Disorders of Glycosylation
No Results Yet
150
Participants
Links Between Inflammation and Cardiometabolic Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2013-12-02
Completion:
2022-08-03
Conditions
Diabetes Mellitus
Cardiovascular Disease
Healthy Volunteer
Inflammation
Interventions
DRUG
No Results Yet
600
Participants
Natural History Study of GATA2 Deficiency and Related Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2013-08-26
Completion:
2028-03-31
Conditions
GATA2 Deficiency
No Results Yet
11
Participants
Skeletal Muscle Biomarkers in People With Fragile Sarcolemmal Muscular Dystrophy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2014-11-03
Completion:
2025-12-31
Conditions
Genetic Disorder
No Results Yet
1313
Participants
S1216, Phase III ADT+TAK-700 vs. ADT+Bicalutamide for Metastatic Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2013-03-08
Completion:
2022-03-08
Conditions
Prostate Cancer
Interventions
DRUG
1000
Participants
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-12-27
Completion:
2029-02-20
Conditions
Neuropsychiatric Disorder
Neurological Disorder
Neurodevelopmental Disorder
Sleep
No Results Yet
37
Participants
Environmental Risk Factors for Myositis in Military Personnel
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2014-03-13
Completion:
2021-10-31
Conditions
Dermatomyositis
Adult Polymyositis
Inclusion Body Myositis
Myositis
No Results Yet
1531
Participants
Retrospective/Prospective Analysis of Surgical Outcomes of Robotic Prostatectomy at The James
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2008-09-23
Completion:
2027-07-31
Conditions
Prostate Cancer
Interventions
PROCEDURE
No Results Yet
181
Participants
Relating Genetic and Environmental Risk Scores to Multiple Sclerosis Susceptibility
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-08-15
Conditions
Multiple Sclerosis
No Results Yet
1651
Participants
Health Outcomes by Neighborhood - Baltimore
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-07-17
Conditions
Stigma
Activity Space
Social Networks
HIV Status
Drug Abuse/Dependence
No Results Yet
9300
Participants
Genetic and Physical Study of Childhood Nerve and Muscle Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-03-20
Conditions
Muscular Dystrophies
Muscle Myopathies
Hereditary Spastic Paraplegias
Inherited Neuropathies
Inherited Neuromuscular Conditions
No Results Yet
310
Participants
Family Genetics Health Education and Healthy Behaviors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-01-03
Conditions
Diabetes
Cancer
Heart Disease
No Results Yet
650
Participants
National Eye Institute Biorepository for Retinal Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2012-06-18
Conditions
Age-Related Macular Degeneration
Diabetic Retinopathy
Von Hippel-Lindau Syndrome
Retinal Disease
Retinal Vein Occlusion
No Results Yet
76
Participants
Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2006-12-05
Conditions
Diffuse Intrinsic Pontine Glioma
PNET
Ependymoma
Germinoma
Medulloblastoma
No Results Yet
4000
Participants
New Heart Imaging Techniques to Evaluate Possible Heart Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2011-07-06
Completion:
2028-11-06
Conditions
Healthy
Obesity
Diabetes
Healthy Volunteers
Atherosclerosis
Interventions
DEVICE
No Results Yet
550
Participants
Acquisition of Blood and Tumor Tissue Samples From Patients With Gastrointestinal Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2011-03-02
Conditions
Non-GI Cancers
Cancer of Gastrointestinal Tract
Gastrointestinal Cancer
No Results Yet
13
Participants
Effect of Aerobic Exercise Training on Cardiorespiratory Function in Patients With Traumatic Brain Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2011-05-26
Completion:
2013-12-31
Conditions
Exercise
Fatigue
Physical Fitness
Traumatic Brain Injury
Interventions
OTHER
No Results Yet
10
Participants
PET Imaging of Patients With Melanoma and Malignant Brain Tumors Using an 124I-labeled cRGDY Silica Nanomolecular Particle Tracer: A Microdosing Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2011-01-31
Completion:
2026-12-31
Conditions
Newly Diagnosed or Recurrent Metastatic Melanoma Patients
Malignant Brain Tumors
Interventions
DRUG
No Results Yet
59
Participants
Developing Biomarkers of Dietary Intake
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2010-10-24
Completion:
2020-03-31
Conditions
Diet Therapy
Healthy Volunteers
Interventions
OTHER
No Results Yet
75
Participants
Water Deprivation Protocol
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2010-10-19
Completion:
2018-09-09
Conditions
Obesity
Interventions
OTHER
No Results Yet
5000
Participants
Characterization of Patients With Uncommon Presentations and/or Uncommon Diseases Associated With the Cardiovascular System
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2010-07-21
Conditions
Metabolic Disease
Obesity
Li-Fraumeni Syndrome
Cardiomyopathy
Atherosclerosis
Inflammatory Disease
Interventions
DEVICE
No Results Yet
886
Participants
Evaluation, Pathogenesis, and Outcome of Subjects With or Suspected Traumatic Brain Injury
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2010-10-07
Conditions
Traumatic Brain Injury
No Results Yet
1000
Participants
Imaging Techniques in MRI
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2010-06-05
Conditions
Cardiac Risk Factors
Healthy
Healthy Volunteers
No Results Yet
1273
Participants
Physiological Investigations of Movement Disorders
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2009-12-08
Completion:
2016-08-17
Conditions
Parkinson's Disease
Tourette's Syndrome
Tic Disorders
Dystonia
Movement Disorders
Interventions
PROCEDURE
DEVICE
OTHER
DIAGNOSTIC_TEST
No Results Yet
600
Participants
The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known Immunocompromise
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2009-10-01
Conditions
EBV
HSV
VZV
HPV
CMV
No Results Yet
236
Participants
Chemotherapy and Pelvic Radiation Therapy With or Without Additional Chemotherapy in Treating Patients With High-Risk Early-Stage Cervical Cancer After Radical Hysterectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-31
Start Date:
2009-09-30
Completion:
2023-12-14
Conditions
Cervical Cancer
Interventions
DRUG
RADIATION
28
Participants
Vasti Control of Patellofemoral Kinematics in Asymptomatic Volunteer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2009-10-22
Conditions
Abnormalities
Patellofemoral Pain Syndrome
No Results Yet
530
Participants
Studies of Skin Microbes in Healthy People and in People With Skin Conditions
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2008-01-22
Conditions
Eczema
Atopic Dermatitis
No Results Yet
200
Participants
Molecular Basis of Human Phagocyte Interactions With Bacterial Pathogens
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-31
Start Date:
2001-02-12
Conditions
Host Defense Mechanisms
No Results Yet
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