Clinical Trials
Showing trials with last updates posted in 2025.
90
Participants
Trastuzumab Rezetecan in Advanced Solid Tumors Refractory to Standard Therapies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-18
Completion:
2027-09-11
Conditions
Urachal Cancer
Advanced Solid Tumor Cancer
Antibody-drug Conjugates
Interventions
DRUG
No Results Yet
30
Participants
Universal CAR-T Cell Injection Targeting CD19/BCMA in Patients With Inflammatory Bowel Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-20
Completion:
2027-12-30
Conditions
Moderate-to-severe Ulcerative Colitis
Crohn's Disease (CD)
Interventions
DRUG
No Results Yet
400
Participants
MPR for Stroke Risk Assessment of ICAS
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2027-12-15
Conditions
ICAS - Intracranial Atherosclerosis
Stroke Ischemic
Hemodynamic
Interventions
DRUG
No Results Yet
400
Participants
Digital Angiography-Derived Fractional Flow Assessment for Intracranial Stenosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2027-01-01
Conditions
Intracranial Atherosclerosis ICAS
Hemodynamic
Stroke
Interventions
DRUG
No Results Yet
106
Participants
Different Modalities for the Evaluation of Patients With Peri-menopausal Bleeding
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-01
Completion:
2026-08-31
Conditions
Perimenopausal Bleeding
Interventions
DIAGNOSTIC_TEST
No Results Yet
38
Participants
The Effects of Magnesium (Mg) Supplement and Alternate Maxillary Expansion and Constriction (Alt-RAMEC) in Patient With Transverse Maxillary Deficiency (TMD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2026-08-12
Conditions
Magnesium During Orthodontic Expansion
Orthodontic Patients Indicated for Maxillary Expansion
Interventions
DIETARY_SUPPLEMENT
No Results Yet
93
Participants
VR Therapy Effects in Lumbar Disc Herniation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2023-11-01
Completion:
2023-12-31
Conditions
Lumbar Disc Herniation
Interventions
OTHER
No Results Yet
70
Participants
Sucrase-Isomaltase (SI) Genes and Meal Load
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-02-01
Completion:
2028-02-01
Conditions
IBS - Irritable Bowel Syndrome
Sucrase-Isomaltase Deficiency
Interventions
DIETARY_SUPPLEMENT
No Results Yet
100
Participants
Hyaluronic Acid in the Treatment of Hyposalivation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-07-01
Completion:
2025-12-19
Conditions
Xerostomia Due to Hyposecretion of Salivary Gland
Interventions
COMBINATION_PRODUCT
No Results Yet
102
Participants
Regional Versus General Anesthesia for Hip Fracture and Postoperative Oxygenation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-27
Completion:
2026-12-31
Conditions
Hip-fracture
General Anaesthesia
Regional Anaesthesia
No Results Yet
10000
Participants
The Extended Study of Prevalence of Infection in Intensive Care IV
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-03-31
Completion:
2026-03-31
Conditions
Sepsis
Infection
No Results Yet
208
Participants
Pragmatic Geriatric Assessment Before CAR-T or Bispecific Antibody Therapy to Predict Side Effects and Outcomes in Older Patients (GA-ACT Trial)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-12
Completion:
2027-12-01
Conditions
Multiple Myeloma (MM), Lymphoma, Large B-Cell, Diffuse (DLBCL), Lymphoma
CART Therapy
Bispecific Antibody
Geriatric Hematology
Interventions
OTHER
No Results Yet
24
Participants
Pharmacokinetics of Didehydro-LSD (DDH-LSD) Compared With LSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-31
Completion:
2028-07-31
Conditions
LSD Reaction
Interventions
DRUG
No Results Yet
150
Participants
A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-18
Completion:
2029-03-31
Conditions
Non-Muscle Invasive Bladder Neoplasms
No Results Yet
350
Participants
Study of Bet v1 Antibodies Effect on Eye Allergy Symptoms in Adolescents and Adults With Birch Pollen Allergy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-19
Completion:
2027-02-28
Conditions
Allergic Conjunctivitis
Interventions
DRUG
No Results Yet
222
Participants
A Phase III Randomized Study of TACE Plus an Oral Triple-Agent Cocktail Versus TACE Plus First-Line Targeted Immunotherapy in Unresectable Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-22
Completion:
2030-06-30
Conditions
Hepatocellular Carcinoma
Interventions
DRUG
DEVICE
No Results Yet
68
Participants
Effect of a Nurse-Led Environmental Stressor Reduction Package on Perceived Stress and Sleep Quality in Intensive Care Unit Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-29
Completion:
2026-01-01
Conditions
Sleep Disturbance
Interventions
BEHAVIORAL
No Results Yet
240
Participants
Impact of Sugammadex Versus Neostigmine on Early Postoperative Pulmonary Function
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-30
Completion:
2026-06-25
Conditions
Residual Neuromuscular Block
Interventions
DRUG
No Results Yet
150
Participants
Phase III Clinical Trial of Hepalatide in Patients With Chronic Hepatitis D
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-04-30
Completion:
2027-06-30
Conditions
Hepatitis D, Chronic
Interventions
DRUG
No Results Yet
100
Participants
Web-based Advance Care Planning Intervention for Patients With Kidney Failure on Dialysis: Pilot Testing of 'My Voice'
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-10-02
Completion:
2026-09-30
Conditions
Kidney Failure, Chronic Therapy; Hemodialysis
Interventions
OTHER
No Results Yet
45
Participants
Tizanidine and Acoustic Reflex
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-07-15
Completion:
2026-02-15
Conditions
Reflex, Acoustic
Hearing
Interventions
DRUG
No Results Yet
54
Participants
Effects of Isotretinoin on Smell
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-06-01
Completion:
2026-03-01
Conditions
Smell Dysfunction
Interventions
DRUG
No Results Yet
220
Participants
Evaluation of the Effectiveness of a Cardiac Coherence Exercise on MRI Success and Image Quality in Claustrophobic Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Claustrophobia
MRI
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Inactivated Bacteroides Fragilis for Prevention of Chemotherapy-Induced Diarrhea
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-15
Completion:
2026-03-30
Conditions
Chemotherapy-induced Diarrhea
Interventions
DRUG
No Results Yet
144
Participants
NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-07-01
Completion:
2029-03-01
Conditions
Metastatic Colorectal Cancer (CRC)
Interventions
DRUG
No Results Yet
864
Participants
A Phase II Clinical Study Evaluating the Combination Therapy of JS212 in Patients With Advanced Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-30
Completion:
2027-11-30
Conditions
Advanced Lung Cancer
Interventions
DRUG
No Results Yet
60
Participants
Comparing the Effects of Smart App-Assited Super-Slow Jogging and Stationary Cycling on Respiratory Function and Aerobic Fitness in College Students
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-20
Completion:
2026-01-31
Conditions
Sedentary Lifestlye
Young Adult
Interventions
BEHAVIORAL
No Results Yet
932
Participants
A Study on Gastrointestinal Transit Time at the Population Level
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-31
Completion:
2026-12-30
Conditions
Gastrointestinal Transit Time
Interventions
OTHER
No Results Yet
30
Participants
Spinning-Based High-Intensity Interval Training Induces Greater Cardiopulmonary Adaptations Than Continuous Training in Sedentary College Men
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2024-08-01
Completion:
2025-01-30
Conditions
Sedentary Lifestlye
Male
Interventions
BEHAVIORAL
No Results Yet
25
Participants
Durvalumab as Consolidation Therapy in Patients With LS-SCLC Following sCRT
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-07-08
Completion:
2025-12-31
Conditions
SCLC, Limited Stage
No Results Yet
66
Participants
Adebrelimab Combined With Famitinib and Irinotecan in Advanced Gastric Cancer After Failure of First-Line Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2024-07-24
Completion:
2027-07-31
Conditions
Stomach Neoplasms
Interventions
DRUG
No Results Yet
34
Participants
KetoBrain: Brain Energy Metabolism in Schizophrenia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-04-15
Completion:
2027-12-15
Conditions
Schizophrenia Disorder
No Results Yet
120
Participants
Impact of Cannabis Consumption on Psychotic Symptoms and Reality Monitoring in Patients With Schizophrenia: a Real-life Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2027-12-31
Conditions
Schizophrenia
Interventions
OTHER
No Results Yet
500
Participants
Single-center Evaluation of Human Milk Quantity and Quality Over Five Years
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-01
Completion:
2026-05-30
Conditions
Lactating Women - Human Milk Donors
Interventions
OTHER
No Results Yet
25
Participants
Local Field Potentials in Dystonia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2025-09-04
Completion:
2028-12-31
Conditions
Dystonia
Dystonia, Focal
Dystonia, Primary
Interventions
DEVICE
No Results Yet
40
Participants
Deep Learning on Amyloid Positons Emission Tomography
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2026-01-06
Completion:
2026-01-20
Conditions
Alzheimer Disease
No Results Yet
250
Participants
Clinical, Morphometric and Biochemical Effects on Adiposopathy Associated With the Use of GLP-1RA in CKD
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-30
Start Date:
2023-09-15
Completion:
2027-07-31
Conditions
Chronic Kidney Disease stage3
Chronic Kidney Disease stage4
Chronic Kidney Disease Stage 1
Chronic Kidney Disease Stage 2
Obesity
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
40
Participants
Effect of Soleus Muscle Kinetic Control Training on Gait and Electromyographic Activity in Patients With Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-15
Completion:
2026-06-15
Conditions
Stroke
Interventions
OTHER
No Results Yet
75
Participants
Acute BFR Training Effects on Balance and Proprioception
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-11-01
Completion:
2025-12-31
Conditions
Blood Flow Restriction
Interventions
OTHER
No Results Yet
201
Participants
A Phase III Study of SHR-1819 Injection in Adolescents With Severe Atopic Dermatitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-30
Start Date:
2025-12-31
Completion:
2027-11-30
Conditions
Adolescents With Moderate-to-severe Atopic Dermatitis
Interventions
DRUG
No Results Yet
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