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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06709924 | COMPLETED
20 Participants

Evaluating Effectiveness of Elevated Intra-abdominal Pressure (IAP) by PressureDOT

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-25
Completion: 2024-12-05
Conditions
Intraabdominal Pressure
Interventions
OTHER
No Results Yet
NCT06709521 | RECRUITING | PHASE4
150 Participants

Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-02-12
Completion: 2026-06-30
Conditions
Bacterial Infection
Interventions
DRUG
No Results Yet
NCT06702306 | ACTIVE_NOT_RECRUITING | NA
70 Participants

Duplex UltraSound afTer Endo Revascularisation - Feasibility Randomised Control Trial (DUSTER)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-14
Completion: 2026-09-01
Conditions
Chronic Limb Threatening Ischaemia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06693687 | RECRUITING | NA
425 Participants

A Study of the ApricityCare Program for Early Detection and Management of Treatment-Related Adverse Events in Patients With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-18
Completion: 2027-11-01
Conditions
Metastatic Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06692907 | ACTIVE_NOT_RECRUITING | PHASE2
72 Participants

Efficacy Study of IM Administered CssBA+dmLT Against Moderate-severe Diarrhea in Human Infection Model With ETEC Strain B7A in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-03-31
Completion: 2026-02-20
Conditions
Escherichia Infection
Interventions
OTHER BIOLOGICAL
No Results Yet
NCT06680037 | RECRUITING | PHASE1
32 Participants

A Study to Assess the Safety and Clinical Activity of Azer-cel in Participants With B-cell Mediated Autoimmune Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-06
Completion: 2026-12-01
Conditions
B-cell Mediated Autoimmune Disorders
Interventions
DRUG
No Results Yet
NCT06671834 | COMPLETED | PHASE1
52 Participants

A Study to Learn About the Study Medicine Called PF-07905428 in Healthy Participants and Participants With Acne Vulgaris

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-22
Completion: 2025-12-04
Conditions
Acne Vulgaris
Interventions
DRUG
No Results Yet
NCT06666647 | ACTIVE_NOT_RECRUITING
2500000 Participants

Response Times in Danish Emergency Medical Services

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-01
Completion: 2026-03-30
Conditions
Emergency Medical Services Response Triage Survival Outcomes Intensive Care Unit Days Intensive Care Patients Invasively Ventilated
Interventions
PROCEDURE
No Results Yet
NCT06654895 | RECRUITING
700 Participants

Multicenter Symphony IL-6 Monitoring Sepsis ICU Validation Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-12
Completion: 2026-08-30
Conditions
Sepsis, Septic Shock
No Results Yet
NCT06652620 | RECRUITING | NA
50 Participants

Cola Ingestion for Esophageal Bolus Impaction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-01
Completion: 2026-01-01
Conditions
Esophageal Cancer
Interventions
OTHER
No Results Yet
NCT06649812 | RECRUITING | PHASE2
120 Participants

Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-07
Completion: 2027-09-01
Conditions
High Grade B-Cell Lymphoma With MYC and BCL6 Rearrangements Recurrent Diffuse Large B-Cell Lymphoma Recurrent Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type Recurrent Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Recurrent High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements Recurrent High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements Recurrent High Grade B-Cell Lymphoma, Not Otherwise Specified Recurrent T-Cell/Histiocyte-Rich Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma Refractory Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type Refractory Diffuse Large B-Cell Lymphoma, Not Otherwise Specified Refractory High Grade B-Cell Lymphoma With MYC and BCL2 or BCL6 Rearrangements Refractory High Grade B-Cell Lymphoma With MYC, BCL2, and BCL6 Rearrangements Refractory High Grade B-Cell Lymphoma, Not Otherwise Specified Refractory T-Cell/Histiocyte-Rich Large B-Cell Lymphoma
Interventions
PROCEDURE DRUG BIOLOGICAL
No Results Yet
NCT06643858 | ENROLLING_BY_INVITATION
10000 Participants

Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-01
Completion: 2025-12-31
Conditions
Healthy Multiple Sclerosis Neuromyelitis Optica Spectrum Disorders Neurodegenerative Diseases Cerebrovascular Diseases
Interventions
OTHER
No Results Yet
NCT06627569 | NOT_YET_RECRUITING | NA
132 Participants

Exercise Effects on the Neurobiology Underlying Stress-related Eating Behaviors in Veterans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-01
Completion: 2030-08-30
Conditions
Overweight/Obesity Stress
Interventions
BEHAVIORAL
No Results Yet
NCT06625060 | RECRUITING | PHASE2
641 Participants

A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-10-10
Completion: 2027-05-31
Conditions
Episodic Migraine Chronic Migraine
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06622681 | RECRUITING
1200 Participants

Integrative Adolescence Research Programme (IARP)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-05-21
Completion: 2026-06-30
Conditions
Executive Dysfunction Physical Stress Mental Health Wellness 1
Interventions
OTHER
No Results Yet
NCT06615908 | RECRUITING | PHASE1
40 Participants

Treatment of Persisting Symptoms After Concussion With Psilocybin Assisted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-27
Completion: 2026-10-30
Conditions
Persisting Symptoms After Concussion
Interventions
DRUG
No Results Yet
NCT06612268 | RECRUITING | PHASE3
408 Participants

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-02-17
Completion: 2027-08-27
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
NCT06612229 | RECRUITING | NA
200 Participants

Biliary Fistulas in Surgery of Liver Echinococcosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-22
Completion: 2026-09-22
Conditions
Echinococcosis, Hepatic Biliary Fistula
Interventions
PROCEDURE
No Results Yet
NCT06611540 | ACTIVE_NOT_RECRUITING | NA
500 Participants

Self-collection for HPV Testing to Improve Cervical Cancer Prevention (SHIP) Trial (LMI-001-A-S03)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-11
Completion: 2026-06-30
Conditions
Cervical Carcinoma Human Papillomavirus Infection
Interventions
PROCEDURE OTHER
No Results Yet
NCT06609226 | RECRUITING | PHASE3
480 Participants

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-10
Completion: 2030-12-30
Conditions
Sickle Cell Disease Thalassemia
Interventions
DRUG
No Results Yet
NCT06606314 | RECRUITING
100 Participants

Specified Drug-use Surveillance of Fabhalta Capsules

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-18
Completion: 2028-09-30
Conditions
Paroxysmal Nocturnal Hemoglobinuria
No Results Yet
NCT06596018 | RECRUITING | PHASE1/PHASE2
96 Participants

Assessing Combined SBRT in Breast Cancer Non-Responders to Neoadjuvant Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-25
Completion: 2027-09-20
Conditions
Breast Adenocarcinoma
Interventions
RADIATION DRUG
No Results Yet
NCT06588530 | COMPLETED | PHASE4
20 Participants

PFAS Exposure and Immune Response to Vaccination in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-11-04
Completion: 2025-01-08
Conditions
Environmental Exposure Vaccine Antibodies Adult Immunity Pollution; Exposure Vaccination Diphtheria Tetanus Innate Inflammatory Response
Interventions
BIOLOGICAL
Results Available
NCT06586957 | RECRUITING | PHASE1
150 Participants

A Study With NKT3964 for Adults With Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-19
Completion: 2029-01-31
Conditions
Solid Tumor Advanced Solid Tumor Solid Tumor, Adult Metastatic Tumor Ovarian Cancer Ovarian Neoplasms Ovarian Carcinoma Metastatic Ovarian Carcinoma Endometrial Neoplasms Endometrial Diseases Metastatic Endometrial Cancer Triple Negative Breast Cancer Metastatic Endometrial Carcinoma Advanced Endometrial Carcinoma Advanced Ovarian Carcinoma Gastric Cancer Advanced Gastric Carcinoma Metastatic Gastric Cancer Metastatic Gastric Carcinoma Small Cell Lung Cancer Small Cell Lung Carcinoma Triple Negative Breast Neoplasms Platinum-resistant Ovarian Cancer Platinum-refractory Ovarian Carcinoma CCNE1 Amplification Hormone Receptor Negative Breast Carcinoma Human Epidermal Growth Factor 2 Negative Carcinoma of Breast Progesterone-receptor-positive Breast Cancer
Interventions
DRUG
No Results Yet
NCT06580951 | NOT_YET_RECRUITING | NA
200 Participants

Regenerative Peripheral Nerve Interface for Prophylaxis Against Post-Breast Surgery Pain Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-03-31
Completion: 2029-03-31
Conditions
Post-mastectomy Pain Syndrome
Interventions
PROCEDURE
No Results Yet
NCT06578754 | NOT_YET_RECRUITING
50 Participants

Validation Testing for Plasma Oxalate Levels in the Biochemical Laboratory at the Galilee Medical Center, in Collaboration With the Biochemistry Laboratory at CHARITE Hospital in Berlin, and Testing the Relationship Between Oxalate Levels and Vitamin C Levels in Plasma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-12-31
Completion: 2026-12-31
Conditions
Hyperoxaluria
Interventions
OTHER
No Results Yet
NCT06570369 | RECRUITING | PHASE1
36 Participants

A Study to Explore the Effect of SP-624 on Brain Network Analytics in Healthy Adults and Adults With Major Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-08-22
Completion: 2026-02-28
Conditions
Major Depressive Disorder Depression Healthy
Interventions
DRUG
No Results Yet
NCT06565260 | RECRUITING | NA
150 Participants

Community-Based Exercise and Nutrition Training and Education Program for Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-02-01
Completion: 2029-08-30
Conditions
Hematopoietic and Lymphatic System Neoplasm Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
NCT06564402 | RECRUITING | NA
40 Participants

Augmentation of Exposure Using Positive Mental Rehearsal in Individuals With Increased Social Anxiety

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-05-28
Completion: 2026-02-01
Conditions
Social Anxiety Social Phobia
Interventions
BEHAVIORAL
No Results Yet
NCT06563895 | RECRUITING | PHASE3
582 Participants

Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-05-12
Completion: 2031-10-31
Conditions
Amyloidosis Amyloid Cardiomyopathy Transthyretin Amyloidosis Cardiomyopathies Heart Diseases Polyneuropathies
Interventions
DRUG
No Results Yet
NCT06561685 | RECRUITING | PHASE1
340 Participants

A Study of LY4050784 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-19
Completion: 2027-10-31
Conditions
Metastatic Solid Tumor Advanced Solid Tumor Non-small Cell Lung Cancer SMARCA4-Deficient Tumor
Interventions
DRUG
No Results Yet
NCT06551519 | RECRUITING
900 Participants

A Non-interventional Study Evaluating Clinical Utility and Implications on Improved Patient Management of Serum Neurofilament as a Prognostic Marker for Disease Activity in Patients With Relapsing Multiple Sclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-10-23
Completion: 2028-11-29
Conditions
Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT06551506 | ACTIVE_NOT_RECRUITING | PHASE4
181 Participants

The Immunology and Safety of Maternal RSV Vaccination (ABRYSVO), Infant Nirsevimab (BEYFORTUS) Immunization, or Both Products

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-19
Completion: 2026-05-31
Conditions
Respiratory Syncytial Virus Infection
Interventions
BIOLOGICAL
No Results Yet
NCT06546137 | RECRUITING
600 Participants

National Network for Cardiovascular Genomics: Advancing Cardiovascular Healthcare for Hereditary Diseases in Brazil's Unified Health System Through a Multicenter Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-30
Completion: 2026-08-31
Conditions
Cardiomyopathy, Hypertrophic Cardiomyopathy, Dilated Cardiomyopathy Restrictive Arrhythmogenic Right Ventricular Dysplasia Non-Compaction Cardiomyopathy Familial Hypercholesterolemia Marfan Syndrome Ehlers-Danlos Syndrome, Vascular Type Loeys-Dietz Syndrome Long QT Syndrome Short Qt Syndrome Brugada Syndrome Catecholaminergic Polymorphic Ventricular Tachycardia Sudden Cardiac Death
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06536504 | RECRUITING | NA
132 Participants

A Randomized Controlled Trial to Assess the Impact of Live and Recorded Music-Based Interventions on Pre-operative Stress, Mood, Pain and Biomarkers, in Neurosurgical Patients (Music-STAR Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-19
Completion: 2027-03-01
Conditions
Stress Pain
Interventions
OTHER
No Results Yet
NCT06535776 | COMPLETED | NA
27 Participants

Effects of Matrix Rhythm Therapy in Axial Spondyloarthritis Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-10-20
Completion: 2025-09-06
Conditions
Functional Status Physical Performance
Interventions
OTHER
No Results Yet
NCT06535568 | NOT_YET_RECRUITING | NA
576 Participants

Single vs. Dual Antiplatelet Therapy in Elderly or HBR Patients Undergoing Percutaneous Intervention With DCB

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-10
Completion: 2026-01-10
Conditions
Coronary Disease Heart Diseases Cardiovascular Diseases Myocardial Ischemia Atherosclerosis Arterial Occlusive Diseases Vascular Diseases Coronary Artery Disease Acute Coronary Syndrome Coronary Stenosis Molecular Mechanisms of Pharmacological Action Enzyme Inhibitors MTOR Inhibitors Protein Kinase Inhibitors Physiological Effects of Drugs Immunosuppressive Agents Antineoplastic Agents High Bleeding Risk Single Antiplatelet Therapy Dual Antiplatelet Therapy Cyclooxygenase Inhibitors P2Y12 Inhibitor Platelet Aggregation Inhibitors Aspirin Clopidogrel
Interventions
DEVICE DRUG
No Results Yet
NCT06527027 | RECRUITING | NA
1000 Participants

LN-RADS, RECIST 1.1 and Node-RADS Classification in the Assessment of Lymph Nodes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-01
Completion: 2028-12-31
Conditions
Lymph Node Neoplasm Lymph Node Metastasis
Interventions
OTHER
No Results Yet
NCT06517719 | RECRUITING
500 Participants

Real-world Experience With Lutetium Vipivotide Tetraxetan in Metastatic Castration Resistant Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-04
Completion: 2028-02-01
Conditions
Metastatic Castration Resistant Prostate Cancer
Interventions
OTHER
No Results Yet
NCT06514521 | RECRUITING
278 Participants

Post Marketing Study on Pluvicto in Korea

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2025-04-18
Completion: 2028-05-31
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
OTHER
No Results Yet
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