Biliary Fistulas in Surgery of Liver Echinococcosis

NCT ID: NCT06612229

Last Updated: 2025-12-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-22

Study Completion Date

2026-12-23

Brief Summary

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The objective of the study is to improving the results of surgical treatment of liver echinococcosis complicated by biliary fistula by optimizing diagnostic approaches to early verification of this complication and improving the tactical and technical aspects of its elimination.

Detailed Description

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Conditions

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Echinococcosis, Hepatic Biliary Fistula

Keywords

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Echinococcosis of the liver Biliary fistula Conservative surgical treatment

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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operation for liver echinococcosis complicated by a biliary fistula

Group Type OTHER

Conservative surgical treatment of liver echinococcosis, verification of occult biliary fistulas and their elimination by weaving and using medical cyanoacrylate glue

Intervention Type PROCEDURE

In conservative surgical operations for liver echinococcosis, the biliary fistula is identified, onto which a U-shaped suture is applied, after which medical cyanoacrylate glue is applied between the suture stitches to the fibrous capsule in the fistula area and the suture threads are tied.

Interventions

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Conservative surgical treatment of liver echinococcosis, verification of occult biliary fistulas and their elimination by weaving and using medical cyanoacrylate glue

In conservative surgical operations for liver echinococcosis, the biliary fistula is identified, onto which a U-shaped suture is applied, after which medical cyanoacrylate glue is applied between the suture stitches to the fibrous capsule in the fistula area and the suture threads are tied.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age under 18 years;
* Informed consent for inclusion in the study;
* The presence of liver echinococcosis, for which conservative surgical treatment will be performed;
* The presence of the entire spectrum of necessary preoperative diagnostic measures;
* A full description of all stages of surgical intervention, indicating the type of intervention (open or laparoscopic surgery, location and size of the echinococcal cyst in the liver, type of antiparasitic treatment, presence or absence of a biliary fistula in the residual cavity, actions taken in relation to the fistula, the option of eliminating the residual cavity and drainage;
* Availability of objective data on the characteristics of the postoperative course, including dynamic indicators of the patient\'s condition, temperature, amount and nature of discharge through the drainage, the time of drainage removal, the type of complications (if any) and the method of their treatment, the duration of the hospital period, data on the characteristics of the posthospital period up to 3 months of observation;
* Absence of concomitant pathology that may affect the outcome of the surgery.

Exclusion Criteria

* Age under 18 years;
* Refusal to participate in the study;
* Extrahepatic echinococcosis without liver damage;
* Absence of the full range of preoperative diagnostic data;
* Difficulties with objective analysis of the features of the performed surgical treatment;
* Incomplete data on monitoring the postoperative hospital and remote (up to 3 months) period;
* The presence of concomitant pathology that may affect the outcome of the operation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Republican Specialized Scientific and Practical Medical Center of Surgery Named After V. Vakhidov

OTHER

Sponsor Role lead

Responsible Party

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Azam Babadjanov

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Republican specialized scientific and practical medical center of surgery named after academician V.Vakhidov

Tashkent, , Uzbekistan

Site Status RECRUITING

Countries

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Uzbekistan

Facility Contacts

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Azam Babadjanov, Professor

Role: primary

Other Identifiers

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27022024

Identifier Type: -

Identifier Source: org_study_id