Clinical Trials

Showing trials with last updates posted in 2025.

NCT06466187 | RECRUITING | PHASE1
365 Participants

A Study of SGN-MesoC2 in Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-08-02
Completion: 2028-05-01
Conditions
Carcinoma, Non-Small-Cell Lung Ovarian Neoplasms Pancreatic Adenocarcinoma Colorectal Neoplasms Mesothelioma Other Solid Tumors Endometrial
Interventions
DRUG
No Results Yet
NCT06462521 | ENROLLING_BY_INVITATION | NA
570 Participants

Cold Snare Piecemeal Resection vs Cold Snare Endoscopic Mucosal Resection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-09-06
Completion: 2027-07-31
Conditions
Colon Cancer Colon Polyp Colon Adenoma Serrated Polyp
Interventions
PROCEDURE
No Results Yet
NCT06452394 | RECRUITING | PHASE2
50 Participants

NEODOXy: Targeting Breast Cancer Stem Cells With Doxycycline

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-16
Completion: 2028-06-30
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT06450028 | COMPLETED | PHASE4
60 Participants

Lidocaine Versus Bupivacaine in Orthognathic Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-07-26
Completion: 2025-11-30
Conditions
Pain, Postoperative Numbness Temperature Sensation Perception of Touch
Interventions
DRUG
No Results Yet
NCT06443931 | COMPLETED | NA
30 Participants

Cryoablation of Intercostal Nerves for Pain Management in Early Postoperative Period in Patients With Minimally Invasive Mitral Valve Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-03-10
Completion: 2025-10-31
Conditions
Mitral Regurgitation Pain, Postoperative
Interventions
PROCEDURE
No Results Yet
NCT06442995 | RECRUITING | PHASE4
290 Participants

Evaluation of the Efficacy of the Addition of Magnesium Sulfate to Morphine on the Occurrence of Acute Urinary Retention Following Epidural Anesthesia for Cesarean Section.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-01-16
Completion: 2027-07-31
Conditions
Urinary Retention
Interventions
DRUG
No Results Yet
NCT06441006 | RECRUITING | PHASE2/PHASE3
400 Participants

Program for Rifampicin-Resistant Disease With Stratified Medicine for Tuberculosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-10-03
Completion: 2031-08-31
Conditions
Tuberculosis, Pulmonary Tuberculosis, Multidrug-Resistant Tuberculosis, MDR
Interventions
DRUG
No Results Yet
NCT06440694 | RECRUITING | PHASE3
150 Participants

Colchicine to Quench the Inflammatory Response After Deep Vein Thrombosis (The Conquer-DVT Pilot Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-07
Completion: 2027-12-01
Conditions
Venous Thromboembolism
Interventions
DRUG
No Results Yet
NCT06437626 | COMPLETED | PHASE3
304 Participants

Efficacy and Safety of Mexidol® in Stroke Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2019-11-18
Completion: 2023-08-18
Conditions
Ischemic Stroke
Interventions
DRUG
NCT06420206 | RECRUITING | NA
200 Participants

Goals of Care Discussion for Patients With Advanced Lung and Gastrointestinal Cancer in the Emergency Department of a Comprehensive Cancer Center

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-05-14
Completion: 2027-02-02
Conditions
Lung Cancer Gastrointestinal Cancer
Interventions
OTHER
No Results Yet
NCT06413160 | NOT_YET_RECRUITING
10000 Participants

The Cardiovascular-Renal-Metabolic (CRM) Syndrome Survey in Jordan

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2026-07-01
Completion: 2027-08-31
Conditions
Cardiovascular-renal-metabolic Syndrome
No Results Yet
NCT06400147 | RECRUITING | NA
38 Participants

Strategy Training for Individuals With Unilateral Neglect

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-08-16
Completion: 2026-01-20
Conditions
Stroke Neglect, Hemispatial
Interventions
BEHAVIORAL
No Results Yet
NCT06396286 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Spine Surgery for Lenke 1 Adolescent Idiopathic Scoliosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-06-12
Completion: 2025-09-29
Conditions
Scoliosis Spine Deformity Adolescent Idiopathic Scoliosis
Interventions
PROCEDURE
No Results Yet
NCT06384222 | RECRUITING | PHASE2
32 Participants

Hyperpolarized (HP) 13C Pyruvate Magnetic Resonance Imaging (MRI) for Response Monitoring to Neoadjuvant Abiraterone

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-12-09
Completion: 2027-09-30
Conditions
High Risk Prostate Carcinoma Prostate Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT06381466 | ACTIVE_NOT_RECRUITING | PHASE1
84 Participants

A Study to Investigate Safety, Tolerability, and Pharmacokinetics of Oral AZD0233 Compared With Placebo in Healthy Adult Participants.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-01
Completion: 2025-12-31
Conditions
Dilated Cardiomyopathy
Interventions
DRUG
No Results Yet
NCT06381115 | RECRUITING | NA
40 Participants

App-Based Optimization of Long-Term CPAP Adherence and Quality of Life

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-06-01
Completion: 2026-06-30
Conditions
Obstructive Sleep Apnea
Interventions
BEHAVIORAL
No Results Yet
NCT06376292 | RECRUITING | PHASE2
58 Participants

A Prospective Single Arm Phase II Exploratory Study on the Combination of Whole Brain Radiotherapy, Thiotepa Intrathecal Injection and Systemic Treatment of Primary Diseases in the Treatment of Solid Tumor Leptomeningeal Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-06
Completion: 2026-01-06
Conditions
Solid Tumor Leptomeningeal Metastasis
Interventions
DRUG
No Results Yet
NCT06368921 | RECRUITING | PHASE1
30 Participants

A Study of Recombinant Oncolytic Virus M1(VRT106) in Patients With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-06-19
Completion: 2026-09-30
Conditions
Solid Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT06367959 | RECRUITING | NA
192 Participants

Health Benefits of Writing Therapy Among Asian American Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-27
Completion: 2026-08-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06361888 | RECRUITING | PHASE2/PHASE3
502 Participants

A Phase II/III Trial to Evaluate the Efficacy and Safety of Surufatinib Combined With Camrelizumab, Nab-paclitaxel, and Gemcitabine in Metastatic Pancreatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-05-08
Completion: 2028-05-31
Conditions
Metastatic Pancreatic Cancer
Interventions
DRUG
No Results Yet
NCT06358885 | ACTIVE_NOT_RECRUITING | NA
3234 Participants

IGHID 12230 - An Implementation Trial of an Experiential Brief Alcohol Intervention for HIV Prevention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-25
Completion: 2026-11-30
Conditions
HIV-1-infection Unhealthy Alcohol Use
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT06349915 | NOT_YET_RECRUITING | NA
46 Participants

A Pilot Evaluation of a Digital Peer Support Intervention for Suicidal Adolescents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-31
Completion: 2027-07-31
Conditions
Suicide
Interventions
BEHAVIORAL
No Results Yet
NCT06334887 | COMPLETED | NA
175 Participants

esTOCma, an App Used by Teachers: an RCT

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-02-26
Completion: 2024-06-30
Conditions
Obsessive-Compulsive Disorder
Interventions
DEVICE
No Results Yet
NCT06331195 | RECRUITING | NA
300 Participants

An Adapted Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Familial Hypercholesterolemia (DICA-FH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-10-23
Completion: 2026-02-28
Conditions
Familial Hypercholesterolemia
Interventions
OTHER DIETARY_SUPPLEMENT
No Results Yet
NCT06325228 | COMPLETED
373 Participants

Musculoskeletal Injuries, Sports Performance, Sports Specialization, and Quality of Life in Young Athletes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-01
Completion: 2025-12-20
Conditions
Sport Injury Healthy Injury;Sports Quality of Life
No Results Yet
NCT06319027 | RECRUITING | PHASE2
100 Participants

Identifying Findings on Brain Scans That Could Help Make Better Predictions About Brain Cancer Progression, The GABLE Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-11
Completion: 2027-05-31
Conditions
Glioblastoma, IDH-Wildtype
Interventions
PROCEDURE OTHER DRUG
No Results Yet
NCT06316154 | RECRUITING
100 Participants

Presentation of Protoscolexes and Acephalocysts in the Fibrous Capsule Area of the Liver With Echinococcosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-22
Completion: 2026-12-22
Conditions
Echinococcosis, Hepatic
Interventions
PROCEDURE
No Results Yet
NCT06315894 | COMPLETED | NA
60 Participants

Supervised Computerized Active Program for People With Post-COVID Syndrome (SuperCAP Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-03
Completion: 2024-09-05
Conditions
Post-COVID Condition
Interventions
DEVICE
No Results Yet
NCT06313918 | RECRUITING | NA
50 Participants

Exercise Therapy in Mental Disorders-study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-09-27
Completion: 2026-09-26
Conditions
Schizophrenia and Related Disorders Bipolar Disorder
Interventions
OTHER
No Results Yet
NCT06310577 | WITHDRAWN | NA
0 Participants

Evaluation of Leak-Free Bronchoscope Adapter to Limit Ventilated Air Volume Loss During Bronchoscopy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-17
Completion: 2026-11-30
Conditions
Pulmonary Disease
Interventions
DEVICE
No Results Yet
NCT06305247 | RECRUITING | PHASE1/PHASE2
220 Participants

A Study to Assess IPN01194 When Administered Alone in Adults With Advanced Solid Tumours

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-03
Completion: 2028-03-20
Conditions
Melanoma Head and Neck Squamous Cell Carcinoma Pancreatic Ductal Adenocarcinoma Colorectal Cancer Solid Tumor
Interventions
DRUG
No Results Yet
NCT06295367 | RECRUITING | NA
760 Participants

Cost Communication and Financial Navigation in Cancer Patients (COSTCOM)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-02-29
Completion: 2027-12-01
Conditions
Malignant Solid Neoplasm
Interventions
OTHER
No Results Yet
NCT06286384 | COMPLETED
30 Participants

Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-03
Completion: 2025-03-10
Conditions
Facial Aging
No Results Yet
NCT06275724 | ACTIVE_NOT_RECRUITING
585 Participants

Specified Drug-use Survey of Leqvio for s.c. Injection.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-03-04
Completion: 2026-12-17
Conditions
Familial Hypercholesterolaemia Hypercholesterolaemia
Interventions
OTHER
No Results Yet
NCT06262919 | RECRUITING
110 Participants

Special Drug Use-results Surveillance of Tafinlar/Mekinist

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2024-02-09
Completion: 2031-12-31
Conditions
BRAF V600E Mutation-positive Unresectable Advanced or Recurrent Solid Tumor
Interventions
DRUG
No Results Yet
NCT06227858 | RECRUITING | NA
104 Participants

Effects of a Standardised Saffron Extract Supplementation on Symptoms Associated With Perimenopause in Healthy Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-08-20
Completion: 2025-12-27
Conditions
Perimenopausal Disorder
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT06198426 | TERMINATED | PHASE1/PHASE2
5 Participants

A Study of IBI3004 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-08-19
Completion: 2025-12-16
Conditions
Solid Tumor
Interventions
DRUG
No Results Yet
NCT06197243 | COMPLETED | NA
23 Participants

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-14
Completion: 2025-05-23
Conditions
Anxiety Insomnia Benzodiazepine Deprescription
Interventions
OTHER
No Results Yet
NCT06182085 | ACTIVE_NOT_RECRUITING | PHASE2
304 Participants

Study to Assess Safety and Efficacy of PRI-002 in Patients With MCI to Mild Dementia Due to Alzheimer's Disease (AD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-01
Completion: 2026-04-30
Conditions
Mild Cognitive Impairment Due to Alzheimer's Disease Alzheimer's Disease, Early Onset
Interventions
DRUG
No Results Yet
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