Clinical Trials

Showing trials with last updates posted in 2025.

NCT05795569 | COMPLETED | NA
112 Participants

Removal of Nasogastric Feeding Tube Post Extubation in ICU : a Prospective Randomized Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-03-21
Completion: 2025-04-10
Conditions
Deglutition Disorders Intensive Care Unit Syndrome Swallowing Disorder Feeding or Eating Disorder
Interventions
PROCEDURE DIAGNOSTIC_TEST
No Results Yet
NCT05776888 | ACTIVE_NOT_RECRUITING
106 Participants

Early Versus Late Ofatumumab (Kesimpta®) Use in Austrian RMS-Patients Over 2 Years

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-10
Completion: 2026-08-31
Conditions
Relapsing Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT05766371 | RECRUITING | PHASE2
48 Participants

Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-12-15
Completion: 2027-05-31
Conditions
Castrate Resistant Prostate Cancer Metastatic Castration-resistant Prostate Cancer Prostate Cancer Prostate Carcinoma
Interventions
DRUG
No Results Yet
NCT05755386 | RECRUITING | PHASE3
106 Participants

Study of Efficacy and Safety of Iptacopan in Participants With IC-MPGN

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-10-02
Completion: 2028-10-27
Conditions
IC-MPGN
Interventions
DRUG
No Results Yet
NCT05752695 | ENROLLING_BY_INVITATION
200 Participants

Operation Korsband

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2023-09-01
Completion: 2028-12-31
Conditions
Anterior Cruciate Ligament Injuries
No Results Yet
NCT05746169 | TERMINATED
1576 Participants

Discovering Cancer Risks From Environmental Contaminants and Maternal/Child Health

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2021-09-01
Completion: 2025-07-21
Conditions
Cancer
Interventions
OTHER
No Results Yet
NCT05740371 | COMPLETED | PHASE4
50 Participants

Safety of Argatroban Infusion in Conduction Disturbances

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2017-04-18
Completion: 2021-05-06
Conditions
Stable Coronary Artery Disease (CAD) Unstable Angina (Troponin Negative)
Interventions
DRUG
NCT05735314 | RECRUITING | NA
450 Participants

A New Combination of Evidence-Based Interventions to Improve Primary Care Diagnostic Safety and Efficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-01-08
Completion: 2026-07-16
Conditions
Anemia Decreased Glomerular Filtration Rate
Interventions
OTHER
No Results Yet
NCT05733767 | RECRUITING | PHASE2
424 Participants

Smoking Cessation Pharmacotherapy-Nurse Practitioner Led Tobacco Treatment Team Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-03
Completion: 2027-08-28
Conditions
Cardiopulmonary Disease Smoking Cessation Inpatient
Interventions
OTHER
No Results Yet
NCT05721989 | COMPLETED | PHASE1
267 Participants

A Research Study Looking Into Blood Levels of Three Different Formulations of the Study Medicine Ziltivekimab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-03
Completion: 2024-01-08
Conditions
Healthy Participants
Interventions
DRUG
No Results Yet
NCT05708235 | RECRUITING | PHASE2
1260 Participants

A PoC Study to Evaluate Treatments' Efficacy by Monitoring MRD Using ctDNA in HR-positive/HER2-negative EBC Population

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-04-01
Completion: 2028-12-30
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05701657 | RECRUITING | NA
8000 Participants

Nutrition for Precision Health, Powered by the All of Us

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-04-14
Completion: 2026-12-31
Conditions
Nutrition Health Dietary Habits
Interventions
OTHER
No Results Yet
NCT05695937 | COMPLETED | NA
58 Participants

Brazilian Cardioprotective Diet, Phytosterols and Krill Oil in Patients With Familial Hypercholesterolemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-05-22
Completion: 2023-12-29
Conditions
Familial Hypercholesterolemia
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT05691244 | RECRUITING | PHASE3
514 Participants

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2025-07-24
Completion: 2026-09-30
Conditions
Acute Ischemic Stroke Cerebral Stroke
Interventions
DRUG
No Results Yet
NCT05689710 | SUSPENDED | NA
30 Participants

The Effects of Inositol on Glucose Metabolism in Patients With Metabolic Syndrome at Risk of Cardiac Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-12-23
Completion: 2026-01-31
Conditions
Metabolic Syndrome Cardiac Fibrosis
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT05685238 | ACTIVE_NOT_RECRUITING | PHASE3
451 Participants

A Research Study Looking at Long-term Treatment With Mim8 in People With Haemophilia A (FRONTIER 4)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-13
Completion: 2028-06-30
Conditions
Haemophilia A Haemophilia A With Inhibitors
Interventions
DRUG
No Results Yet
NCT05678530 | RECRUITING
1000 Participants

Observational, Non-Interventional Study Supporting Validation of VO2Max Estimation Methods Using Results in Patients Receiving Standard of Care Cardiopulmonary Exercise Tests (CPET)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2019-06-06
Completion: 2027-03-31
Conditions
Cardiopulmonary
No Results Yet
NCT05673005 | COMPLETED | NA
20 Participants

MED3000 Topical Gel for On-Demand Treatment of Post-Radical Prostatectomy Erectile Dysfunction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-04-01
Completion: 2024-07-24
Conditions
Erectile Dysfunction Following Radical Prostatectomy
Interventions
DEVICE
NCT05650632 | RECRUITING | PHASE1
180 Participants

A Study to Assess Adverse Events of Intravenously (IV) Infused ABBV-383 in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-03-21
Completion: 2029-08-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05642533 | COMPLETED
1061 Participants

Obesity and Cardiovascular Diseases, Cross-sectional Study in Saudi Arabia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2022-12-31
Completion: 2023-09-14
Conditions
Obesity and Cardiovascular Risk
Interventions
OTHER
No Results Yet
NCT05635747 | ENROLLING_BY_INVITATION
32 Participants

A 90 Day Observational Study as an Extension to the Phase 3,Open Labeled Exploratory Study of RELiZORB

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2022-09-29
Completion: 2026-09-29
Conditions
Short Bowel Syndrome Malabsorption
Interventions
DEVICE
No Results Yet
NCT05617625 | SUSPENDED | PHASE2
50 Participants

CD34+ Enriched Transplants to Treat Myelodysplastic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-31
Completion: 2032-09-30
Conditions
Myelodysplastic Syndromes Graft Vs Host Disease Graft-versus-host-disease
Interventions
DRUG DEVICE
No Results Yet
NCT05614739 | RECRUITING | PHASE1
535 Participants

FORAGER-1: A Study of LOXO-435 (LY3866288) in Participants With Cancer With a Change in a Gene Called FGFR3

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-01-12
Completion: 2027-06-30
Conditions
Urinary Bladder Neoplasms Neoplasm Metastasis Ureteral Neoplasms
Interventions
DRUG
No Results Yet
NCT05606614 | RECRUITING | PHASE3
15 Participants

A Phase 1/2/3 Study of TSHA-102 Gene Therapy in Females With Rett Syndrome (REVEAL Pivotal Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-03-06
Completion: 2031-06-30
Conditions
Rett Syndrome
Interventions
GENETIC
No Results Yet
NCT05587530 | TERMINATED | NA
7 Participants

Zero Suicide Implementation in Outpatient Mental Health Clinics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-20
Completion: 2025-05-31
Conditions
Suicide
Interventions
BEHAVIORAL
NCT05568615 | COMPLETED | PHASE3
15 Participants

Extension Study Following the Studies MT-1186-A03 or A04 to Evaluate the Safety of Oral Edaravone in Subjects With ALS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-10-26
Completion: 2023-06-27
Conditions
ALS
Interventions
DRUG
NCT05565105 | NOT_YET_RECRUITING | PHASE2
100 Participants

CD34+ Transplants for Leukemia and Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2026-01-31
Completion: 2032-09-30
Conditions
Leukemia, Myeloid, Acute Leukemia, Lymphocytic, Acute
Interventions
RADIATION DRUG
No Results Yet
NCT05556798 | ACTIVE_NOT_RECRUITING | PHASE1
9 Participants

A Study of Belantamab Mafodotin in Combination With Nirogacestat and Pomalidomide in People With Multiple Myeloma That Has Not Responded to Treatment or Has Come Back After Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-10-04
Completion: 2026-10-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05551273 | ACTIVE_NOT_RECRUITING | PHASE2
29 Participants

Study of Oral TLR8 Agonist Selgantolimod on HBsAg in Participants With Both Chronic Hepatitis B and HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-05-05
Completion: 2025-10-29
Conditions
Hepatitis B HIV Infections
Interventions
DRUG
No Results Yet
NCT05538663 | RECRUITING | PHASE3
870 Participants

Intravesical BCG vs GEMDOCE in NMIBC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-02-07
Completion: 2029-11-01
Conditions
Non-muscle-invasive Bladder Cancer
Interventions
DRUG
No Results Yet
NCT05532319 | COMPLETED | PHASE2
64 Participants

HAIC Sequential TAE Combined With Lenvatinib and Tislelizumab in Unresectable HCC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-10
Completion: 2025-12-23
Conditions
Liver Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05494190 | RECRUITING | NA
111 Participants

The Management of Metastatic Neck Nodes in N2/3 Hypopharyngeal Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-01
Completion: 2027-11-30
Conditions
Hypopharyngeal Carcinoma
Interventions
DRUG RADIATION PROCEDURE
No Results Yet
NCT05480384 | ACTIVE_NOT_RECRUITING | PHASE2
1 Participants

Adjuvant Trastuzumab Deruxtecan (Enhertu) & Nivolumab For Patients Who Are Disease Free After Completion of Trimodality Treatment For HER-2+ Cancers of Esophagus & Gastroesophageal Junction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2023-07-14
Completion: 2025-04-09
Conditions
Esophageal Cancer Esophageal Adenocarcinoma HER-2 Protein Overexpression Gastroesophageal-junction Cancer
Interventions
DRUG
No Results Yet
NCT05470595 | ACTIVE_NOT_RECRUITING | PHASE2
67 Participants

A Single-arm Trial of Atezolizumab/Platinum/Etoposide for the Treatment of Advanced Large-cell Neuroendocrine Cancer of the Lung

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-01-18
Completion: 2028-01-31
Conditions
Large Cell Neuroendocrine Carcinoma of the Lung
Interventions
DRUG
No Results Yet
NCT05468320 | COMPLETED | PHASE3
51 Participants

Caplacizumab and Immunosuppressive Therapy Without Firstline Therapeutic Plasma Exchange in Adults With Immune-mediated Thrombotic Thrombocytopenic Purpura

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-11-21
Completion: 2024-12-26
Conditions
Thrombotic Thrombocytopenic Purpura
Interventions
DRUG BIOLOGICAL
NCT05450172 | COMPLETED
204 Participants

Impact of Postoperative Transitional Pain on Recovery After Thoracic Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2022-10-10
Completion: 2024-03-10
Conditions
Postoperative Recovery
Interventions
OTHER
No Results Yet
NCT05443191 | COMPLETED
50 Participants

A Research Study Looking at How Oral Semaglutide Works in People With Type 2 Diabetes in Finland, as Part of Local Clinical Practice

Study Type: OBSERVATIONAL
Last Updated: 2025-12-30
Start Date: 2022-10-20
Completion: 2023-04-27
Conditions
Diabetes Mellitus, Type 2
Interventions
DRUG
No Results Yet
NCT05436379 | COMPLETED | NA
21 Participants

Treatment, Emotion, and Neuromodulation of Depression (TREND) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-06-17
Completion: 2025-11-30
Conditions
Depression
Interventions
DEVICE
No Results Yet
NCT05435508 | COMPLETED | NA
62 Participants

Efficacy of Pain Neuroscience Education and Pre-anesthetic Assessment in Reducing Levels of Anxiety, Stress and Pain in Patients Undergoing Elective Total Abdominal Hysterectomy (ENAH Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2024-07-01
Completion: 2025-02-28
Conditions
Pain, Chronic Pain, Postoperative Anesthesia Surgery Anxiety Stress
Interventions
OTHER
No Results Yet
NCT05433168 | COMPLETED | NA
72 Participants

Study Evaluating the Effectiveness of Shiatsu on Fatigue in Patients With Axial Spondyloarthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-30
Start Date: 2022-09-20
Completion: 2024-12-10
Conditions
Spondyloarthritis
Interventions
PROCEDURE
No Results Yet
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