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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07172776 | NOT_YET_RECRUITING | NA
50 Participants

A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2026-12-31
Conditions
Oral Cancers
Interventions
BEHAVIORAL
No Results Yet
NCT07166757 | RECRUITING | PHASE1/PHASE2
90 Participants

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-22
Completion: 2028-03-30
Conditions
Parkinson Disease (PD)
Interventions
DRUG
No Results Yet
NCT07165067 | RECRUITING | PHASE1
36 Participants

A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-21
Completion: 2027-12-27
Conditions
Solid Tumours
Interventions
DRUG
No Results Yet
NCT07162922 | COMPLETED | NA
76 Participants

Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-17
Completion: 2025-12-21
Conditions
Increased Intracranial Pressure Disorders Perioperative Complication Pneumoperitoneum
Interventions
OTHER
No Results Yet
NCT07157787 | RECRUITING | PHASE2
30 Participants

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-19
Completion: 2027-02-12
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT07157124 | RECRUITING | NA
62 Participants

Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-22
Completion: 2026-09-30
Conditions
Craving Alcohol Drinking
Interventions
OTHER
No Results Yet
NCT07155174 | RECRUITING | PHASE2
180 Participants

A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-11-25
Completion: 2029-05-31
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07154667 | RECRUITING | NA
30 Participants

Evaluation of the Auryzon™ EAR 2.0 System in Ear Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-01
Completion: 2030-12-31
Conditions
Ear Deformities, Acquired Ear Deformity External Ear Malformation Ear Cartilage Microtia, Congenital Microtia Microtia-Anotia
Interventions
PROCEDURE
No Results Yet
NCT07151261 | RECRUITING | NA
54 Participants

Ashwagandha for Nighttime Waking

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-20
Completion: 2026-02-28
Conditions
Disturbed Sleep
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07148089 | RECRUITING | PHASE1
18 Participants

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-05
Completion: 2027-06-30
Conditions
Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions
DRUG
No Results Yet
NCT07147608 | RECRUITING
118 Participants

SAPHIR2 : Simplification of PHysical Activity Assessment by Rapid Interrogation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-19
Completion: 2027-06-30
Conditions
General Population (no Specific Condition or Disease)
Interventions
OTHER
No Results Yet
NCT07128199 | RECRUITING | PHASE3
360 Participants

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-11-30
Completion: 2029-10-01
Conditions
NSCLC, Stage IB-IIIA Lung Cancer Adjuvant Post-surgical EGFR Exon 20 Early Stage Lung Cancer Uncommon EGFR Mutations
Interventions
DRUG
No Results Yet
NCT07124975 | ENROLLING_BY_INVITATION | NA
186 Participants

Impact of Comparing Treatment Status With Other CPAP Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-01
Completion: 2027-12-31
Conditions
Sleep Apnea Obstructive Sleep Apnea
Interventions
BEHAVIORAL
No Results Yet
NCT07122219 | RECRUITING | NA
548 Participants

Enhancing Uptake of Needle and Syringe Programs in Canadian Federal Prisons

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-01
Completion: 2028-02-29
Conditions
HIV Hepatitis C Virus (HCV)
Interventions
BEHAVIORAL
No Results Yet
NCT07106970 | RECRUITING | NA
640 Participants

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-28
Completion: 2027-09-30
Conditions
Persistent Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
NCT07102056 | NOT_YET_RECRUITING
152 Participants

18F-AlF-NOTA-Octreotide PET in Neuroendocrine Neoplasms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2027-06-03
Conditions
Neuroendocrine Tumors
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07100210 | RECRUITING | PHASE1
6 Participants

A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-20
Completion: 2026-02-20
Conditions
Refractory Malignant Solid Tumors mRNA Vaccine Interleukin
Interventions
BIOLOGICAL
No Results Yet
NCT07100067 | RECRUITING | NA
35 Participants

LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-16
Completion: 2028-02-20
Conditions
Relapsed/Refractory Multiple Myeloma(MM)
Interventions
BIOLOGICAL
No Results Yet
NCT07096726 | NOT_YET_RECRUITING | NA
200 Participants

Boston Medical Center Ultrasound Decongestion Study in Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-02-28
Completion: 2027-10-31
Conditions
Congestive Heart Failure Volume Overload
Interventions
DEVICE OTHER
No Results Yet
NCT07094581 | RECRUITING
72 Participants

Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-20
Completion: 2026-02-09
Conditions
Adenoid Hypertrophy Masseter Muscle Malocclusion
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07092384 | COMPLETED | NA
265 Participants

Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-30
Completion: 2025-11-30
Conditions
Remifentanil Adverse Effects
Interventions
DRUG
No Results Yet
NCT07090148 | RECRUITING | PHASE1
14 Participants

Trial of pTVG-HP+Nivo+Targeted Ablation of Resistant Lesions in Non-Castrate RecurrentOMPC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-31
Completion: 2030-09-30
Conditions
Prostate Cancer Patients Non-castrate Prostate Cancer Recurrent Prostate Cancer Oligometastatic Prostate Cancer (OMPC)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT07086820 | RECRUITING | NA
647 Participants

Window Prophylaxis for Pediatric Tuberculosis Prevention Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-27
Completion: 2028-05-31
Conditions
Tuberculosis Infection Household Contacts Children Adolescent Tuberculosis Infection, Latent Tuberculosis
Interventions
DRUG
No Results Yet
NCT07070791 | RECRUITING | NA
40 Participants

Combined Upper Extremity Resistance and Aerobic Exercise Training in Patients With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-08
Completion: 2026-05-01
Conditions
Breast Cancer Upper Extremity Resistance Exercise Aerobic Exercise
Interventions
OTHER
No Results Yet
NCT07070778 | RECRUITING | NA
18 Participants

Arterial Stiffness in Individuals With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-08
Completion: 2026-11-01
Conditions
Aerobic Exercise Breast Cancer Arterial Stiffness
Interventions
OTHER
No Results Yet
NCT07063173 | RECRUITING | NA
15 Participants

Bioavailability of Ration Items Containing Tart Cherry Extract

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-06-14
Completion: 2025-12-31
Conditions
Bioavailability
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07058454 | RECRUITING
5000 Participants

Multicenter Prospective Observational Study of Cardiotoxicity in Patients Receiving Targeted Cancer Therapies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-01
Completion: 2027-09-01
Conditions
Cancer;Cardiovascular;Adverse Events Cancer
No Results Yet
NCT07051954 | RECRUITING | NA
40 Participants

Effectiveness of Functional Respiratory Muscle Training in Post-COVID-19 Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-15
Completion: 2025-12-20
Conditions
Post COVID-19 Syndrome Functional Inspiratory Muscle Training Core Stabilization
Interventions
OTHER
No Results Yet
NCT07050485 | ENROLLING_BY_INVITATION | NA
30 Participants

Postbiotics for Mitigation of Postoperative Dysbiosis in Gastrointestinal Cancer Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-15
Completion: 2026-04-30
Conditions
Colon Cancer Gastrointestinal Cancer
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07050277 | RECRUITING | PHASE3
50 Participants

Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-24
Completion: 2027-07-01
Conditions
Arthroplasties, Knee Replacement Nerve Block Urinary Retention Postoperative Anesthesia, Spinal
Interventions
DRUG
No Results Yet
NCT07040956 | RECRUITING | PHASE2
98 Participants

A Clinical Trial Comparing Low-Dose RT + Targeted Therapy+ Immunotherapy vs Targeted Therapy+ Immunotherapy Alone as Neoadjuvant Therapy in Operable HNSCC Patients.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-28
Completion: 2026-07-01
Conditions
Head and Neck Squamous Cell Carcinoma Low-dose Radiotherapy Immunotherapy Targeted Therapy
Interventions
DRUG RADIATION
No Results Yet
NCT07031791 | RECRUITING
200 Participants

PETRA: Pictorial Assessment of Task Occurrence and Upper Limb Avoidance Behaviors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-27
Completion: 2027-07-01
Conditions
Thoraco-brachial Outlet Syndrome ADAP-shoulder Scale PETRA
Interventions
OTHER
No Results Yet
NCT07029737 | RECRUITING | PHASE2
55 Participants

A Study to Evaluate Acalabrutinib, in Combination With the R-CHOP Standard of Care, for Previously Untreated Mantle Cell Lymphoma in Spain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-05
Completion: 2027-06-15
Conditions
Mantle-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT07024693 | RECRUITING | PHASE2
28 Participants

DT-168 in Keratoplasty Patients With Fuchs Endothelial Corneal Dystrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-30
Completion: 2026-09-30
Conditions
Fuchs Endothelial Corneal Dystrophy Fuchs
Interventions
DRUG
No Results Yet
NCT07023107 | COMPLETED | PHASE4
60 Participants

NLR and PLR Levels Following PENG Block in Hip Arthroplasty

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-16
Completion: 2025-12-09
Conditions
Hip Arthropathy Hip Osteoarthritis Hip Pain Chronic
Interventions
DRUG
No Results Yet
NCT07021222 | NOT_YET_RECRUITING | NA
150 Participants

Multifactorial Strategies for the Prevention of the Risks of Ulceration in Patients Affected by Diabetic Foot (DARE-DiaFoot)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-09-01
Completion: 2026-10-15
Conditions
Diabetes Mellitus Foot Ulcer
Interventions
PROCEDURE
No Results Yet
NCT07013487 | RECRUITING | PHASE3
12000 Participants

A Study to Evaluate V181 Dengue Vaccine in Healthy Participants 2 to 17 Years of Age (V181-005/MOBILIZE-1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-11
Completion: 2032-02-02
Conditions
Healthy
Interventions
BIOLOGICAL
No Results Yet
NCT07008001 | RECRUITING | NA
175 Participants

Assessment of DOT Spectacles in Chinese Children Extension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-01
Completion: 2026-09-30
Conditions
Juvenile Myopia Myopia
Interventions
DEVICE
No Results Yet
NCT07007091 | ACTIVE_NOT_RECRUITING | PHASE1
260 Participants

A Study to Assess the Relative Bioavailability of Risankizumab Following Subcutaneous Administrations With a Pre-Filled Syringe or an On-Body Injector in Healthy Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-06-12
Completion: 2025-12-31
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT07006727 | RECRUITING | PHASE1
116 Participants

Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-16
Completion: 2031-06-17
Conditions
Small Cell Lung Carcinoma Large Cell Neuroendocrine Carcinoma of the Lung Neuroendocrine Prostate Cancer Gastroenteropancreatic Neuroendocrine Carcinoma
Interventions
DRUG
No Results Yet
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