Clinical Trials
Showing trials with last updates posted in 2025.
200
Participants
Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-30
Completion:
2027-04-30
Conditions
Bipolar I or II Disorder
Interventions
DRUG
No Results Yet
22
Participants
Ayahuasca and Esketamine for Major Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2022-10-30
Completion:
2024-10-30
Conditions
Major Depression Severe
Interventions
DRUG
No Results Yet
99
Participants
A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-05
Completion:
2027-03-14
Conditions
Thyroid Eye Disease (TED)
Interventions
DRUG
No Results Yet
256
Participants
Physician- and Patient-based Barriers to NGS Testing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-15
Completion:
2027-09-01
Conditions
Metastatic Prostate Cancer
Interventions
OTHER
No Results Yet
172
Participants
Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-31
Completion:
2027-04-01
Conditions
Depression - Major Depressive Disorder
Interventions
DRUG
No Results Yet
100
Participants
Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-22
Completion:
2026-10-01
Conditions
Carotid Artery Disease
Carotid Artery Stenoses
Interventions
DRUG
No Results Yet
60
Participants
Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-31
Completion:
2028-08-31
Conditions
Metastatic Cancer
Interventions
DRUG
No Results Yet
125
Participants
A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-04
Completion:
2030-12-31
Conditions
Solid Tumors Harboring MET Amplification
Interventions
DRUG
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-29
No Results Yet
80
Participants
Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-01
Completion:
2027-06-30
Conditions
Post Traumatic Headache
Interventions
DRUG
OTHER
No Results Yet
124
Participants
A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-26
Completion:
2028-06-28
Conditions
Immunoglobulin G4 Related Disease
Interventions
DRUG
No Results Yet
58
Participants
Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-24
Completion:
2026-01-01
Conditions
PONV
BIS
Interventions
DIAGNOSTIC_TEST
No Results Yet
200
Participants
IntHyx : Intubation Strategies for Patients With Acute Hypoxemic Respiratory Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-13
Completion:
2026-12-31
Conditions
Acute Hypoxemic Respiratory Failure
Interventions
PROCEDURE
No Results Yet
237
Participants
Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-03-01
Completion:
2029-03-29
Conditions
Lung Carcinoma
Interventions
BEHAVIORAL
OTHER
No Results Yet
60
Participants
Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-16
Completion:
2025-12-20
Conditions
Neuromuscular Block, Residual
Pain Management
Postoperative Nausea
Interventions
DRUG
No Results Yet
108
Participants
Cardiac Anodal Biphasic Pacing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-02-28
Completion:
2027-07-31
Conditions
Cardiac Pacing
Interventions
DEVICE
No Results Yet
50
Participants
A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-01
Completion:
2026-12-31
Conditions
Oral Cancers
Interventions
BEHAVIORAL
No Results Yet
90
Participants
Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-22
Completion:
2028-03-30
Conditions
Parkinson Disease (PD)
Interventions
DRUG
No Results Yet
36
Participants
A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-21
Completion:
2027-12-27
Conditions
Solid Tumours
Interventions
DRUG
No Results Yet
76
Participants
Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-17
Completion:
2025-12-21
Conditions
Increased Intracranial Pressure Disorders
Perioperative Complication
Pneumoperitoneum
Interventions
OTHER
No Results Yet
30
Participants
Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-19
Completion:
2027-02-12
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
62
Participants
Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-22
Completion:
2026-09-30
Conditions
Craving
Alcohol Drinking
Interventions
OTHER
No Results Yet
180
Participants
A Study to Evaluate the Optimal Dose, Adverse Events and Change in Disease Activity of Intravenous ABBV-706 in Combination With Atezolizumab Versus Standard of Care as First-Line Treatment in Adult Participants With Previously Untreated Extensive Stage Small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-11-25
Completion:
2029-05-31
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
30
Participants
Evaluation of the Auryzonâ„¢ EAR 2.0 System in Ear Reconstruction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-10-01
Completion:
2030-12-31
Conditions
Ear Deformities, Acquired
Ear Deformity External
Ear Malformation
Ear Cartilage
Microtia, Congenital
Microtia
Microtia-Anotia
Interventions
PROCEDURE
No Results Yet
54
Participants
Ashwagandha for Nighttime Waking
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-10-20
Completion:
2026-02-28
Conditions
Disturbed Sleep
Interventions
DIETARY_SUPPLEMENT
OTHER
No Results Yet
18
Participants
A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-05
Completion:
2027-06-30
Conditions
Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions
DRUG
No Results Yet
118
Participants
SAPHIR2 : Simplification of PHysical Activity Assessment by Rapid Interrogation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2025-12-19
Completion:
2027-06-30
Conditions
General Population (no Specific Condition or Disease)
Interventions
OTHER
No Results Yet
200
Participants
Study to Assess Change in Disease Activity of Risankizumab Treatment in Japanese Participants With Moderate to Severe Ulcerative Colitis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2025-10-09
Completion:
2030-02-28
Conditions
Ulcerative Colitis
No Results Yet
1602
Participants
Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-26
Completion:
2026-01-28
Conditions
Meningococcal Infection
Healthy Volunteers
Interventions
BIOLOGICAL
No Results Yet
360
Participants
A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-11-30
Completion:
2029-10-01
Conditions
NSCLC, Stage IB-IIIA
Lung Cancer
Adjuvant
Post-surgical
EGFR
Exon 20
Early Stage Lung Cancer
Uncommon EGFR Mutations
Interventions
DRUG
No Results Yet
186
Participants
Impact of Comparing Treatment Status With Other CPAP Users
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-10-01
Completion:
2027-12-31
Conditions
Sleep Apnea
Obstructive Sleep Apnea
Interventions
BEHAVIORAL
No Results Yet
548
Participants
Enhancing Uptake of Needle and Syringe Programs in Canadian Federal Prisons
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2024-10-01
Completion:
2028-02-29
Conditions
HIV
Hepatitis C Virus (HCV)
Interventions
BEHAVIORAL
No Results Yet
640
Participants
PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-08-28
Completion:
2027-09-30
Conditions
Persistent Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
152
Participants
18F-AlF-NOTA-Octreotide PET in Neuroendocrine Neoplasms
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2026-01-01
Completion:
2027-06-03
Conditions
Neuroendocrine Tumors
Interventions
DIAGNOSTIC_TEST
No Results Yet
6
Participants
A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-01-20
Completion:
2026-02-20
Conditions
Refractory Malignant Solid Tumors
mRNA Vaccine
Interleukin
Interventions
BIOLOGICAL
No Results Yet
35
Participants
LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-09-16
Completion:
2028-02-20
Conditions
Relapsed/Refractory Multiple Myeloma(MM)
Interventions
BIOLOGICAL
No Results Yet
200
Participants
Boston Medical Center Ultrasound Decongestion Study in Heart Failure
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-02-28
Completion:
2027-10-31
Conditions
Congestive Heart Failure
Volume Overload
Interventions
DEVICE
OTHER
No Results Yet
60
Participants
Safety, Reactogenicity, and Immunogenicity Trial of STX-S SARS-CoV-2 Vaccine in Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-08-11
Completion:
2026-02-02
Conditions
COVID-19
Interventions
BIOLOGICAL
No Results Yet
72
Participants
Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2024-07-20
Completion:
2026-02-09
Conditions
Adenoid Hypertrophy
Masseter Muscle
Malocclusion
Interventions
DIAGNOSTIC_TEST
No Results Yet
265
Participants
Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-07-30
Completion:
2025-11-30
Conditions
Remifentanil
Adverse Effects
Interventions
DRUG
No Results Yet
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