Clinical Trials

Showing trials with last updates posted in 2025.

NCT07220460 | RECRUITING | PHASE2
200 Participants

Study to Assess the Adverse Events of Oral ABBV-932 in Adult Participants With Depressive Episodes Associated With Bipolar I or II Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-30
Completion: 2027-04-30
Conditions
Bipolar I or II Disorder
Interventions
DRUG
No Results Yet
NCT07212946 | COMPLETED | PHASE2
22 Participants

Ayahuasca and Esketamine for Major Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-10-30
Completion: 2024-10-30
Conditions
Major Depression Severe
Interventions
DRUG
No Results Yet
NCT07211776 | RECRUITING | PHASE3
99 Participants

A Study to Assess the Efficacy and Safety of ZL-1109 in Chinese Participants With Active Thyroid Eye Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-05
Completion: 2027-03-14
Conditions
Thyroid Eye Disease (TED)
Interventions
DRUG
No Results Yet
NCT07209176 | NOT_YET_RECRUITING | NA
256 Participants

Physician- and Patient-based Barriers to NGS Testing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-15
Completion: 2027-09-01
Conditions
Metastatic Prostate Cancer
Interventions
OTHER
No Results Yet
NCT07203144 | NOT_YET_RECRUITING | PHASE2
172 Participants

Selenium Supplementation for Improving Depression in Children and Adolescents: Efficacy and Mechanistic Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-31
Completion: 2027-04-01
Conditions
Depression - Major Depressive Disorder
Interventions
DRUG
No Results Yet
NCT07200180 | RECRUITING | PHASE3
100 Participants

Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-22
Completion: 2026-10-01
Conditions
Carotid Artery Disease Carotid Artery Stenoses
Interventions
DRUG
No Results Yet
NCT07197671 | NOT_YET_RECRUITING | PHASE1
60 Participants

Y-NM600 in Patients Receiving Anti-PD-1 or Anti-PD-L1 for Metastatic Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-31
Completion: 2028-08-31
Conditions
Metastatic Cancer
Interventions
DRUG
No Results Yet
NCT07196644 | RECRUITING | PHASE2
125 Participants

A Study to Assess Adverse Events and Change in Disease Activity in Participants 12 Years of Age or Older With Locally Advanced or Metastatic Solid Tumors That Harbor MET Amplification Receiving Intravenously Infused Telisotuzumab Adizutecan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-04
Completion: 2030-12-31
Conditions
Solid Tumors Harboring MET Amplification
Interventions
DRUG
No Results Yet
NCT07191145 | NOT_YET_RECRUITING | PHASE3
80 Participants

Eary Infusion of Eptinezumab for TreatmEnt of ACute Post-Traumatic Headaches (ELITE-ACT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2027-06-30
Conditions
Post Traumatic Headache
Interventions
DRUG OTHER
No Results Yet
NCT07190196 | RECRUITING | PHASE3
124 Participants

A 52-week Study of Rilzabrutinib Efficacy and Safety Compared to Placebo in Adults Diagnosed With IgG4-related Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-26
Completion: 2028-06-28
Conditions
Immunoglobulin G4 Related Disease
Interventions
DRUG
No Results Yet
NCT07189845 | RECRUITING | NA
58 Participants

Effect of BIS-Guided Anesthesia on Postoperative Nausea and Vomiting in Pediatric Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-24
Completion: 2026-01-01
Conditions
PONV BIS
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07189078 | RECRUITING | NA
200 Participants

IntHyx : Intubation Strategies for Patients With Acute Hypoxemic Respiratory Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-13
Completion: 2026-12-31
Conditions
Acute Hypoxemic Respiratory Failure
Interventions
PROCEDURE
No Results Yet
NCT07176000 | NOT_YET_RECRUITING | NA
237 Participants

Tailored Patient Navigation to Improve the Uptake of Lung Cancer Screening in Tribal Communities in Western Washington State, SACRED LUNGS Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-03-01
Completion: 2029-03-29
Conditions
Lung Carcinoma
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07175623 | COMPLETED | NA
60 Participants

Methylprednisolone vs Dexamethasone Interaction With Sugammadex in Pediatric Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-16
Completion: 2025-12-20
Conditions
Neuromuscular Block, Residual Pain Management Postoperative Nausea
Interventions
DRUG
No Results Yet
NCT07173777 | NOT_YET_RECRUITING | NA
108 Participants

Cardiac Anodal Biphasic Pacing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-02-28
Completion: 2027-07-31
Conditions
Cardiac Pacing
Interventions
DEVICE
No Results Yet
NCT07172776 | NOT_YET_RECRUITING | NA
50 Participants

A Community Engagement Approach to Improving Communication With Black Men About Oral and Pharyngeal Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2026-12-31
Conditions
Oral Cancers
Interventions
BEHAVIORAL
No Results Yet
NCT07166757 | RECRUITING | PHASE1/PHASE2
90 Participants

Clinical Study to Evaluate XS411 in Treatment of Early-onset Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-22
Completion: 2028-03-30
Conditions
Parkinson Disease (PD)
Interventions
DRUG
No Results Yet
NCT07165067 | RECRUITING | PHASE1
36 Participants

A Study of AP601 in Patients With Locally Unresectable Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-21
Completion: 2027-12-27
Conditions
Solid Tumours
Interventions
DRUG
No Results Yet
NCT07162922 | COMPLETED | NA
76 Participants

Optic Nerve Sheath Diameter Changes in Laparoscopic Cholecystectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-17
Completion: 2025-12-21
Conditions
Increased Intracranial Pressure Disorders Perioperative Complication Pneumoperitoneum
Interventions
OTHER
No Results Yet
NCT07157787 | RECRUITING | PHASE2
30 Participants

Study of ALXN1920 in Adult Participants With Primary Membranous Nephropathy (PMN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-19
Completion: 2027-02-12
Conditions
Primary Membranous Nephropathy
Interventions
DRUG
No Results Yet
NCT07157124 | RECRUITING | NA
62 Participants

Examining the Effectiveness of Dynamic Visual Noise (DVN) for Reducing Alcohol Cravings and Consumption in College Students

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-22
Completion: 2026-09-30
Conditions
Craving Alcohol Drinking
Interventions
OTHER
No Results Yet
NCT07155174 | RECRUITING | PHASE2
180 Participants
NCT07154667 | RECRUITING | NA
30 Participants

Evaluation of the Auryzonâ„¢ EAR 2.0 System in Ear Reconstruction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-01
Completion: 2030-12-31
Conditions
Ear Deformities, Acquired Ear Deformity External Ear Malformation Ear Cartilage Microtia, Congenital Microtia Microtia-Anotia
Interventions
PROCEDURE
No Results Yet
NCT07151261 | RECRUITING | NA
54 Participants

Ashwagandha for Nighttime Waking

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-20
Completion: 2026-02-28
Conditions
Disturbed Sleep
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT07148089 | RECRUITING | PHASE1
18 Participants

A Study of SGT-501 Gene Therapy in Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-05
Completion: 2027-06-30
Conditions
Catecholaminergic Polymorphic Ventricular Tachycardia
Interventions
DRUG
No Results Yet
NCT07147608 | RECRUITING
118 Participants

SAPHIR2 : Simplification of PHysical Activity Assessment by Rapid Interrogation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-12-19
Completion: 2027-06-30
Conditions
General Population (no Specific Condition or Disease)
Interventions
OTHER
No Results Yet
NCT07136116 | RECRUITING
200 Participants

Study to Assess Change in Disease Activity of Risankizumab Treatment in Japanese Participants With Moderate to Severe Ulcerative Colitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-09
Completion: 2030-02-28
Conditions
Ulcerative Colitis
No Results Yet
NCT07135986 | RECRUITING | PHASE3
1602 Participants

Immunogenicity and Safety Study of an Investigational Quadrivalent Meningococcal Conjugate Vaccine Administered in Healthy Children and Adolescents in China

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-26
Completion: 2026-01-28
Conditions
Meningococcal Infection Healthy Volunteers
Interventions
BIOLOGICAL
No Results Yet
NCT07128199 | RECRUITING | PHASE3
360 Participants

A Study to Assess the Efficacy and Safety of Zipalertinib Versus Placebo for Adjuvant Treatment in Participants With Stage IB-IIIA NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-11-30
Completion: 2029-10-01
Conditions
NSCLC, Stage IB-IIIA Lung Cancer Adjuvant Post-surgical EGFR Exon 20 Early Stage Lung Cancer Uncommon EGFR Mutations
Interventions
DRUG
No Results Yet
NCT07124975 | ENROLLING_BY_INVITATION | NA
186 Participants

Impact of Comparing Treatment Status With Other CPAP Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-10-01
Completion: 2027-12-31
Conditions
Sleep Apnea Obstructive Sleep Apnea
Interventions
BEHAVIORAL
No Results Yet
NCT07122219 | RECRUITING | NA
548 Participants

Enhancing Uptake of Needle and Syringe Programs in Canadian Federal Prisons

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2024-10-01
Completion: 2028-02-29
Conditions
HIV Hepatitis C Virus (HCV)
Interventions
BEHAVIORAL
No Results Yet
NCT07106970 | RECRUITING | NA
640 Participants

PVI Alone vs PVI and Linear Ablation for Persistent Atrial Fibrillation (PROMPT AF II)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-28
Completion: 2027-09-30
Conditions
Persistent Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
NCT07102056 | NOT_YET_RECRUITING
152 Participants

18F-AlF-NOTA-Octreotide PET in Neuroendocrine Neoplasms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2026-01-01
Completion: 2027-06-03
Conditions
Neuroendocrine Tumors
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07100210 | RECRUITING | PHASE1
6 Participants

A Clinical Trial Evaluating IL-22BP/LNP Compound in Refractory Malignant Solid Tumors for Safety, Tolerability and Activity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-01-20
Completion: 2026-02-20
Conditions
Refractory Malignant Solid Tumors mRNA Vaccine Interleukin
Interventions
BIOLOGICAL
No Results Yet
NCT07100067 | RECRUITING | NA
35 Participants

LCAR-F33S in Treatment of Relapsed/Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-09-16
Completion: 2028-02-20
Conditions
Relapsed/Refractory Multiple Myeloma(MM)
Interventions
BIOLOGICAL
No Results Yet
NCT07096726 | NOT_YET_RECRUITING | NA
200 Participants

Boston Medical Center Ultrasound Decongestion Study in Heart Failure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-02-28
Completion: 2027-10-31
Conditions
Congestive Heart Failure Volume Overload
Interventions
DEVICE OTHER
No Results Yet
NCT07095231 | RECRUITING | PHASE1
60 Participants

Safety, Reactogenicity, and Immunogenicity Trial of STX-S SARS-CoV-2 Vaccine in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-08-11
Completion: 2026-02-02
Conditions
COVID-19
Interventions
BIOLOGICAL
No Results Yet
NCT07094581 | RECRUITING
72 Participants

Evaluation of the Effect of Adenoid Hypertrophy on the Masseter Muscle in Children: A Comparative Ultrasonographic Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2024-07-20
Completion: 2026-02-09
Conditions
Adenoid Hypertrophy Masseter Muscle Malocclusion
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07092384 | COMPLETED | NA
265 Participants

Effect of Remifentanil on Pruritus and Paresthesia of Fospropofol Disodium Anesthesia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2025-07-30
Completion: 2025-11-30
Conditions
Remifentanil Adverse Effects
Interventions
DRUG
No Results Yet
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