Clinical Trials
Showing trials with last updates posted in 2025.
416
Participants
Study of Denikitug (GS-1811) Given Alone or With Zimberelimab in Adults With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-08-18
Completion:
2028-12-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
92
Participants
A Study in Adults With Ulcerative Colitis (UC) or Crohn's Disease (CD) Receiving Vedolizumab in Real-World Practice in Switzerland
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2021-09-08
Completion:
2024-05-17
Conditions
Inflammatory Bowel Diseases
Crohns Disease
Colitis, Ulcerative
No Results Yet
44
Participants
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-08-11
Completion:
2026-12-31
Conditions
Dental Implant
Bone Loss
Interventions
BIOLOGICAL
No Results Yet
280
Participants
SleepUp Digital CBTi-based Platform for Insomnia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2025-05-19
Completion:
2025-11-18
Conditions
Insomnia
Sleep Disorder
Sleep Hygiene
Interventions
BEHAVIORAL
No Results Yet
8
Participants
Examining the Effectiveness of Deep TMS in Veterans With Alcohol Use Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2022-09-06
Completion:
2023-11-17
Conditions
Alcohol Use Disorder (AUD)
Transcranial Magnetic Stimulation
Interventions
DEVICE
Compassionate Use of Concizumab if You Have Haemophilia
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-29
Conditions
Congenital Haemophilia
Interventions
DRUG
No Results Yet
1081
Participants
A Study to Learn More About the Long-term Safety and Effectiveness of Molidustat as a Treatment for Japanese Men and Women With Renal Anemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2021-08-06
Completion:
2027-06-30
Conditions
Renal Anemia
Interventions
DRUG
No Results Yet
133
Participants
Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-10-01
Completion:
2024-10-21
Conditions
Obesity
Obesity & Overweight
Interventions
OTHER
No Results Yet
3
Participants
Open-Label Prospective Study Comparing Long-Term Outcome With or Without HFNC in Patients With Stable Hypercapnic COPD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2022-04-21
Completion:
2024-04-30
Conditions
COPD
Interventions
DEVICE
OTHER
No Results Yet
152
Participants
A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-12-20
Completion:
2026-05-31
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
2540
Participants
Long-term Beta-blocker Therapy After Acute Myocardial Infarction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-05-04
Completion:
2026-01-31
Conditions
Myocardial Infarction
Interventions
DRUG
No Results Yet
100
Participants
Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-01-15
Completion:
2027-05-22
Conditions
Endometrial Cancer
Interventions
RADIATION
OTHER
No Results Yet
50
Participants
Refining Local-Regional Therapy for IBC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-06-02
Completion:
2027-12-01
Conditions
Breast Cancer
Inflammatory Breast Cancer
Sentinel Lymph Node
Interventions
PROCEDURE
No Results Yet
83
Participants
A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-11-23
Completion:
2027-12-31
Conditions
Muscular Dystrophy, Duchenne
Interventions
GENETIC
No Results Yet
186
Participants
Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-02-24
Completion:
2029-06-30
Conditions
Stage II Gallbladder Cancer AJCC v8
Stage IIA Gallbladder Cancer AJCC v8
Stage IIB Gallbladder Cancer AJCC v8
Stage III Gallbladder Cancer AJCC v8
Stage IIIA Gallbladder Cancer AJCC v8
Stage IIIB Gallbladder Cancer AJCC v8
Interventions
DRUG
PROCEDURE
No Results Yet
148
Participants
Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-12-10
Completion:
2025-09-19
Conditions
Thrombotic Microangiopathy
Interventions
BIOLOGICAL
OTHER
No Results Yet
1000
Participants
Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2020-11-09
Completion:
2025-12-19
Conditions
Atherosclerosis
Interventions
OTHER
No Results Yet
125
Participants
A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-08-25
Completion:
2025-05-10
Conditions
AL Amyloidosis
Interventions
DRUG
OTHER
No Results Yet
150
Participants
Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-02-09
Completion:
2026-08-29
Conditions
Advanced Melanoma
Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Melanoma of Unknown Primary
Pathologic Stage IIIB Cutaneous Melanoma AJCC v8
Pathologic Stage IIIC Cutaneous Melanoma AJCC v8
Pathologic Stage IIID Cutaneous Melanoma AJCC v8
Pathologic Stage IV Cutaneous Melanoma AJCC v8
Unresectable Acral Lentiginous Melanoma
Unresectable Melanoma
Unresectable Mucosal Melanoma
Interventions
BIOLOGICAL
OTHER
No Results Yet
0
Participants
Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2026-06-01
Completion:
2027-07-01
Conditions
COVID-19
ARDS
Acute Respiratory Distress Syndrome
Interventions
BIOLOGICAL
OTHER
No Results Yet
62
Participants
Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-01-29
Completion:
2025-06-13
Conditions
Major Depressive Disorder
Interventions
DEVICE
No Results Yet
300
Participants
Follow-up Study of ICUS and CCUS Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2011-01-01
Completion:
2026-12-31
Conditions
Myelodysplastic Syndromes
Interventions
OTHER
No Results Yet
4789
Participants
Evaluation of Changes in Weight, Sleep, and Other Psycho-behavioural Parameters During Covid-19 Confinement in Subjects Monitored by the RNPC Network
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2020-05-08
Completion:
2020-06-08
Conditions
Comorbidities
Confinement
Obesity
No Results Yet
2606
Participants
Safety and Efficacy Study of Meningococcal Group B Vaccine rMenB+OMV NZ (Bexsero) to Prevent Gonococcal Infection
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-12-29
Completion:
2026-02-26
Conditions
Gonococcal Infection
Interventions
BIOLOGICAL
OTHER
No Results Yet
138
Participants
Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-09-15
Completion:
2027-08-31
Conditions
Anatomic Stage IV Breast Cancer AJCC v8
Hormone Receptor Positive Breast Carcinoma
Metastatic Breast Carcinoma
Prognostic Stage IV Breast Cancer AJCC v8
Interventions
PROCEDURE
OTHER
No Results Yet
30
Participants
Exercise in Children Attention Deficit Hyperactivity Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2019-10-10
Completion:
2022-08-10
Conditions
ADHD
Exercise
Interventions
OTHER
No Results Yet
41
Participants
Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-10-15
Completion:
2025-08-04
Conditions
Atopic Dermatitis
Staphylococcus Aureus
Bacterial Toxins
Immune Response
Cytokines
T Cells Subsets
Interventions
OTHER
No Results Yet
2175
Participants
CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-03-13
Completion:
2026-10-31
Conditions
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage IIA Breast Cancer AJCC v8
Anatomic Stage IIB Breast Cancer AJCC v8
Anatomic Stage IIIA Breast Cancer AJCC v8
Invasive Breast Carcinoma
Prognostic Stage II Breast Cancer AJCC v8
Prognostic Stage IIA Breast Cancer AJCC v8
Prognostic Stage IIB Breast Cancer AJCC v8
Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions
DRUG
PROCEDURE
BIOLOGICAL
RADIATION
No Results Yet
1300
Participants
Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2022-02-21
Completion:
2027-12-31
Conditions
AORTIC VALVE DISEASES
Thromboembolism
Interventions
DRUG
No Results Yet
236
Participants
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-05-21
Completion:
2027-05-01
Conditions
Myelodysplastic Syndromes
Acute Myeloid Leukemia
Myelodysplastic Syndrome/Neoplasm
Chronic Myelomonocytic Leukemia
Interventions
DRUG
No Results Yet
314
Participants
Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-05-26
Completion:
2028-03-31
Conditions
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8
Clinical Stage IV Gastric Cancer AJCC v8
Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8
Clinical Stage IVA Gastric Cancer AJCC v8
Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8
Clinical Stage IVB Gastric Cancer AJCC v8
Metastatic Esophageal Adenocarcinoma
Metastatic Gastric Adenocarcinoma
Oligometastatic Esophageal Adenocarcinoma
Oligometastatic Gastric Adenocarcinoma
Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IV Gastric Cancer AJCC v8
Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8
Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
Interventions
DRUG
RADIATION
No Results Yet
4606
Participants
Comparing Two Methods to Follow Patients With Pancreatic Cysts
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-06-16
Completion:
2037-06-03
Conditions
Pancreatic Carcinoma
Interventions
PROCEDURE
OTHER
No Results Yet
176
Participants
Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-08-26
Completion:
2026-06-30
Conditions
Metastatic Pancreatic Adenocarcinoma
Stage IV Pancreatic Cancer AJCC v8
Interventions
DRUG
OTHER
No Results Yet
50
Participants
7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2021-04-12
Completion:
2025-09-02
Conditions
Systemic Sclerosis (SSc)
Magnetic Resonance Imaging (MRI)
Interventions
DEVICE
No Results Yet
400
Participants
Inpatient Stroke Recovery Using Sensors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-29
Start Date:
2017-10-31
Completion:
2026-12-31
Conditions
Stroke
Interventions
DIAGNOSTIC_TEST
No Results Yet
252
Participants
Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-01-02
Completion:
2029-12-31
Conditions
Anal Basaloid Carcinoma
Anal Canal Cloacogenic Carcinoma
Anal Canal Squamous Cell Carcinoma
Anal Margin Squamous Cell Carcinoma
Stage I Anal Cancer AJCC v8
Stage IIA Anal Cancer AJCC v8
Interventions
PROCEDURE
DRUG
OTHER
RADIATION
No Results Yet
260
Participants
Health Coaching for Chronic Multisymptom Illness
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-04-30
Completion:
2025-05-01
Conditions
Pain Predominant Chronic Multisymptom Illness
Interventions
BEHAVIORAL
No Results Yet
360
Participants
A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2019-12-13
Completion:
2026-12-31
Conditions
Liver Lymphoma
Mantle Cell Lymphoma
Interventions
DRUG
BIOLOGICAL
No Results Yet
54
Participants
A Study Combining the Peposertib (M3814) Pill With Standard Chemotherapy in Patients With Ovarian Cancer With an Expansion in High Grade Serous Ovarian Cancer and Low Grade Serous Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2020-05-07
Completion:
2026-06-01
Conditions
Endometrial High Grade Endometrioid Adenocarcinoma
Fallopian Tube Carcinosarcoma
Fallopian Tube Clear Cell Adenocarcinoma
Fallopian Tube Endometrioid Adenocarcinoma
Fallopian Tube High Grade Serous Adenocarcinoma
Fallopian Tube Mucinous Adenocarcinoma
Fallopian Tube Transitional Cell Carcinoma
Fallopian Tube Undifferentiated Carcinoma
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma
FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma
Ovarian High Grade Serous Adenocarcinoma
Ovarian Seromucinous Carcinoma
Ovarian Undifferentiated Carcinoma
Platinum-Sensitive Ovarian Carcinoma
Primary Peritoneal Carcinosarcoma
Primary Peritoneal High Grade Serous Adenocarcinoma
Primary Peritoneal Transitional Cell Carcinoma
Primary Peritoneal Undifferentiated Carcinoma
Recurrent Fallopian Tube Carcinoma
Recurrent Low Grade Fallopian Tube Serous Adenocarcinoma
Recurrent Ovarian Carcinoma
Recurrent Ovarian Carcinosarcoma
Recurrent Ovarian Clear Cell Adenocarcinoma
Recurrent Ovarian Endometrioid Adenocarcinoma
Recurrent Ovarian Low Grade Serous Adenocarcinoma
Recurrent Ovarian Mucinous Adenocarcinoma
Recurrent Ovarian Transitional Cell Carcinoma
Recurrent Primary Peritoneal Carcinoma
Recurrent Primary Peritoneal Low Grade Serous Adenocarcinoma
Interventions
PROCEDURE
DRUG
No Results Yet
40
Participants
A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-29
Start Date:
2019-09-26
Completion:
2022-12-16
Conditions
Non-small Cell Lung Cancer
Colorectal Cancer
Pancreatic Ductal Carcinoma
Esophageal Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
Breast Cancer
Other Solid Tumors
Interventions
DRUG
No Results Yet
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