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Clinical Trials

Showing trials with last updates posted in 2025.

NCT04850391 | COMPLETED | NA
133 Participants

Interaction of Sleep, Diurnal Eating Pattern, Gut Microbiota, and Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-10-01
Completion: 2024-10-21
Conditions
Obesity Obesity & Overweight
Interventions
OTHER
No Results Yet
NCT04840706 | TERMINATED | NA
3 Participants

Open-Label Prospective Study Comparing Long-Term Outcome With or Without HFNC in Patients With Stable Hypercapnic COPD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-04-21
Completion: 2024-04-30
Conditions
COPD
Interventions
DEVICE OTHER
No Results Yet
NCT04819100 | ACTIVE_NOT_RECRUITING | PHASE3
152 Participants

A Study of Selpercatinib After Surgery or Radiation in Participants With Non-Small Cell Lung Cancer (NSCLC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-12-20
Completion: 2026-05-31
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
NCT04769362 | RECRUITING | PHASE4
2540 Participants

Long-term Beta-blocker Therapy After Acute Myocardial Infarction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-05-04
Completion: 2026-01-31
Conditions
Myocardial Infarction
Interventions
DRUG
No Results Yet
NCT04683653 | RECRUITING | PHASE1/PHASE2
100 Participants

Study of Pelvic Hypofractionated Radiotherapy in Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-01-15
Completion: 2027-05-22
Conditions
Endometrial Cancer
Interventions
RADIATION OTHER
No Results Yet
NCT04636710 | RECRUITING | NA
50 Participants

Refining Local-Regional Therapy for IBC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-06-02
Completion: 2027-12-01
Conditions
Breast Cancer Inflammatory Breast Cancer Sentinel Lymph Node
Interventions
PROCEDURE
No Results Yet
NCT04626674 | RECRUITING | PHASE1
83 Participants

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-11-23
Completion: 2027-12-31
Conditions
Muscular Dystrophy, Duchenne
Interventions
GENETIC
No Results Yet
NCT04559139 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
186 Participants

Comparison of Chemotherapy Before and After Surgery Versus After Surgery Alone for the Treatment of Gallbladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-02-24
Completion: 2029-06-30
Conditions
Stage II Gallbladder Cancer AJCC v8 Stage IIA Gallbladder Cancer AJCC v8 Stage IIB Gallbladder Cancer AJCC v8 Stage III Gallbladder Cancer AJCC v8 Stage IIIA Gallbladder Cancer AJCC v8 Stage IIIB Gallbladder Cancer AJCC v8
Interventions
DRUG PROCEDURE
No Results Yet
NCT04543591 | ACTIVE_NOT_RECRUITING | PHASE3
148 Participants

Ravulizumab in Thrombotic Microangiopathy After Hematopoietic Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-12-10
Completion: 2025-09-19
Conditions
Thrombotic Microangiopathy
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04523194 | ACTIVE_NOT_RECRUITING
1000 Participants

Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2020-11-09
Completion: 2025-12-19
Conditions
Atherosclerosis
Interventions
OTHER
No Results Yet
NCT04504825 | ACTIVE_NOT_RECRUITING | PHASE3
125 Participants

A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIb AL Amyloidosis (CARES)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-08-25
Completion: 2025-05-10
Conditions
AL Amyloidosis
Interventions
DRUG OTHER
No Results Yet
NCT04462406 | RECRUITING | PHASE2
150 Participants

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-02-09
Completion: 2026-08-29
Conditions
Advanced Melanoma Clinical Stage III Cutaneous Melanoma AJCC v8 Clinical Stage IV Cutaneous Melanoma AJCC v8 Melanoma of Unknown Primary Pathologic Stage IIIB Cutaneous Melanoma AJCC v8 Pathologic Stage IIIC Cutaneous Melanoma AJCC v8 Pathologic Stage IIID Cutaneous Melanoma AJCC v8 Pathologic Stage IV Cutaneous Melanoma AJCC v8 Unresectable Acral Lentiginous Melanoma Unresectable Melanoma Unresectable Mucosal Melanoma
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04452097 | WITHDRAWN | PHASE1/PHASE2
0 Participants

Use of hUC-MSC Product (BX-U001) for the Treatment of COVID-19 With ARDS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-06-01
Completion: 2027-07-01
Conditions
COVID-19 ARDS Acute Respiratory Distress Syndrome
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT04448327 | ACTIVE_NOT_RECRUITING | NA
62 Participants

Impact of Transcutaneous Vagal Nerve Stimulation on Stress Response in Major Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-01-29
Completion: 2025-06-13
Conditions
Major Depressive Disorder
Interventions
DEVICE
No Results Yet
NCT04428489 | ENROLLING_BY_INVITATION
300 Participants

Follow-up Study of ICUS and CCUS Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2011-01-01
Completion: 2026-12-31
Conditions
Myelodysplastic Syndromes
Interventions
OTHER
No Results Yet
NCT04409197 | COMPLETED
4789 Participants

Evaluation of Changes in Weight, Sleep, and Other Psycho-behavioural Parameters During Covid-19 Confinement in Subjects Monitored by the RNPC Network

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2020-05-08
Completion: 2020-06-08
Conditions
Comorbidities Confinement Obesity
No Results Yet
NCT04316117 | ACTIVE_NOT_RECRUITING | PHASE2
138 Participants

Using FDG-PET/CT to Assess Response of Bone-Dominant Metastatic Breast Cancer, FEATURE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-09-15
Completion: 2027-08-31
Conditions
Anatomic Stage IV Breast Cancer AJCC v8 Hormone Receptor Positive Breast Carcinoma Metastatic Breast Carcinoma Prognostic Stage IV Breast Cancer AJCC v8
Interventions
PROCEDURE OTHER
No Results Yet
NCT04279652 | COMPLETED | NA
30 Participants

Exercise in Children Attention Deficit Hyperactivity Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-10-10
Completion: 2022-08-10
Conditions
ADHD Exercise
Interventions
OTHER
No Results Yet
NCT04274348 | COMPLETED | NA
41 Participants

Staphylococcal Toxins in Atopic Dermatitis and Eczema Herpeticum

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-10-15
Completion: 2025-08-04
Conditions
Atopic Dermatitis Staphylococcus Aureus Bacterial Toxins Immune Response Cytokines T Cells Subsets
Interventions
OTHER
No Results Yet
NCT04266249 | ACTIVE_NOT_RECRUITING | PHASE2
2175 Participants

CompassHER2-pCR: Decreasing Chemotherapy for Breast Cancer Patients After Pre-surgery Chemo and Targeted Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-03-13
Completion: 2026-10-31
Conditions
Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage IIA Breast Cancer AJCC v8 Anatomic Stage IIB Breast Cancer AJCC v8 Anatomic Stage IIIA Breast Cancer AJCC v8 Invasive Breast Carcinoma Prognostic Stage II Breast Cancer AJCC v8 Prognostic Stage IIA Breast Cancer AJCC v8 Prognostic Stage IIB Breast Cancer AJCC v8 Prognostic Stage IIIA Breast Cancer AJCC v8
Interventions
DRUG PROCEDURE BIOLOGICAL RADIATION
No Results Yet
NCT04258488 | RECRUITING | PHASE4
1300 Participants

Long-term Anticoagulation With Oral Factor Xa Inhibitor Versus Vitamin K Antagonist After Mechanical Aortic Valve Replacement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2022-02-21
Completion: 2027-12-31
Conditions
AORTIC VALVE DISEASES Thromboembolism
Interventions
DRUG
No Results Yet
NCT04256317 | RECRUITING | PHASE2/PHASE3
236 Participants

A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-05-21
Completion: 2027-05-01
Conditions
Myelodysplastic Syndromes Acute Myeloid Leukemia Myelodysplastic Syndrome/Neoplasm Chronic Myelomonocytic Leukemia
Interventions
DRUG
No Results Yet
NCT04248452 | RECRUITING | PHASE3
314 Participants

Testing the Addition of Radiotherapy to the Usual Treatment (Chemotherapy) for Patients With Esophageal and Gastric Cancer That Has Spread to a Limited Number of Other Places in the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-05-26
Completion: 2028-03-31
Conditions
Clinical Stage IV Esophageal Adenocarcinoma AJCC v8 Clinical Stage IV Gastric Cancer AJCC v8 Clinical Stage IVA Esophageal Adenocarcinoma AJCC v8 Clinical Stage IVA Gastric Cancer AJCC v8 Clinical Stage IVB Esophageal Adenocarcinoma AJCC v8 Clinical Stage IVB Gastric Cancer AJCC v8 Metastatic Esophageal Adenocarcinoma Metastatic Gastric Adenocarcinoma Oligometastatic Esophageal Adenocarcinoma Oligometastatic Gastric Adenocarcinoma Pathologic Stage IV Esophageal Adenocarcinoma AJCC v8 Pathologic Stage IV Gastric Cancer AJCC v8 Pathologic Stage IVA Esophageal Adenocarcinoma AJCC v8 Pathologic Stage IVB Esophageal Adenocarcinoma AJCC v8
Interventions
DRUG RADIATION
No Results Yet
NCT04239573 | ACTIVE_NOT_RECRUITING | NA
4606 Participants

Comparing Two Methods to Follow Patients With Pancreatic Cysts

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-06-16
Completion: 2037-06-03
Conditions
Pancreatic Carcinoma
Interventions
PROCEDURE OTHER
No Results Yet
NCT04233866 | ACTIVE_NOT_RECRUITING | PHASE2
176 Participants

Comparing Two Treatment Combinations, Gemcitabine and Nab-Paclitaxel With 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan for Older Patients With Pancreatic Cancer That Has Spread

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-08-26
Completion: 2026-06-30
Conditions
Metastatic Pancreatic Adenocarcinoma Stage IV Pancreatic Cancer AJCC v8
Interventions
DRUG OTHER
No Results Yet
NCT04223817 | COMPLETED | NA
50 Participants

7.0 Tesla Resonance Magnetic Imaging of the Hand in Systemic Sclerosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2021-04-12
Completion: 2025-09-02
Conditions
Systemic Sclerosis (SSc) Magnetic Resonance Imaging (MRI)
Interventions
DEVICE
No Results Yet
NCT04219670 | RECRUITING
400 Participants

Inpatient Stroke Recovery Using Sensors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2017-10-31
Completion: 2026-12-31
Conditions
Stroke
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04166318 | ACTIVE_NOT_RECRUITING | PHASE2
252 Participants

Lower-Dose Chemoradiation in Treating Patients With Early-Stage Anal Cancer, the DECREASE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-01-02
Completion: 2029-12-31
Conditions
Anal Basaloid Carcinoma Anal Canal Cloacogenic Carcinoma Anal Canal Squamous Cell Carcinoma Anal Margin Squamous Cell Carcinoma Stage I Anal Cancer AJCC v8 Stage IIA Anal Cancer AJCC v8
Interventions
PROCEDURE DRUG OTHER RADIATION
No Results Yet
NCT04157101 | COMPLETED | NA
260 Participants

Health Coaching for Chronic Multisymptom Illness

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-04-30
Completion: 2025-05-01
Conditions
Pain Predominant Chronic Multisymptom Illness
Interventions
BEHAVIORAL
No Results Yet
NCT04115631 | ACTIVE_NOT_RECRUITING | PHASE2
360 Participants

A Comparison of Three Chemotherapy Regimens for the Treatment of Patients With Newly Diagnosed Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-12-13
Completion: 2026-12-31
Conditions
Liver Lymphoma Mantle Cell Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT04045496 | COMPLETED | PHASE1
40 Participants

A First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-09-26
Completion: 2022-12-16
Conditions
Non-small Cell Lung Cancer Colorectal Cancer Pancreatic Ductal Carcinoma Esophageal Squamous Cell Carcinoma Head and Neck Squamous Cell Carcinoma Breast Cancer Other Solid Tumors
Interventions
DRUG
No Results Yet
NCT04031040 | ACTIVE_NOT_RECRUITING | NA
110 Participants

A Post-market Clinical Follow up of the Genio® System for the Treatment of Obstructive Sleep Apnea in Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-09-01
Completion: 2026-10-30
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
No Results Yet
NCT03992651 | COMPLETED | NA
20 Participants

Optical Transcutaneous Sensors of Capnia and Oxygenation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-06-12
Completion: 2019-06-13
Conditions
Blood Gas Monitoring, Transcutaneous
Interventions
DEVICE
No Results Yet
NCT03875755 | ACTIVE_NOT_RECRUITING | NA
1080 Participants

Myo-inositol for Reduction of Insulin Therapy in Gestational Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-03-04
Completion: 2026-09-20
Conditions
Gestational Diabetes Mellitus
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT03869216 | COMPLETED | NA
161 Participants

Fostering Shared Decision-making About Prostate Cancer Screening Among Clinicians and African American Men

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2020-08-17
Completion: 2023-11-30
Conditions
Prostate Cancer
Interventions
BEHAVIORAL
Results Available
NCT03857191 | COMPLETED
396 Participants

Nutritional Rehabilitation and Sleep Apnea in the Obese

Study Type: OBSERVATIONAL
Last Updated: 2025-12-29
Start Date: 2019-03-22
Completion: 2022-04-11
Conditions
Obese Sleep Apnea, Obstructive
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT03780062 | COMPLETED | PHASE3
720 Participants

Interest of S100B Protein for Patient Victim of Minor Traumatic Brain Injury and Treated by Antiplatelet

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-01-25
Completion: 2025-04-28
Conditions
Minor Traumatic Brain Injury Treatment by Antiplatelet
Interventions
BIOLOGICAL
No Results Yet
NCT03760731 | COMPLETED | NA
74 Participants

Thriving in the Midst of Moral Pain: The Acceptability and Feasibility of Acceptance and Commitment Therapy for Moral Injury (ACT-MI) Among Warzone Veterans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-04-01
Completion: 2024-10-31
Conditions
Moral Injury
Interventions
BEHAVIORAL
Results Available
NCT03734731 | NOT_YET_RECRUITING | NA
1000 Participants

Cannabis Vs Opioids Pain Management Objective Testing Comparisons

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2026-06-03
Completion: 2027-02-03
Conditions
Chronic Pain Circulatory Disorders
Interventions
DEVICE DRUG
No Results Yet
NCT03729180 | RECRUITING | NA
1900 Participants

The ImPreSS Trial: Pharmacogenomic Decision Making at Time of Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-29
Start Date: 2019-01-22
Completion: 2027-08-22
Conditions
Surgery
Interventions
PROCEDURE DIAGNOSTIC_TEST OTHER
No Results Yet
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