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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06950294 | NOT_YET_RECRUITING | EARLY_PHASE1
34 Participants

iNO300 Therapy in Critically Ill Patients With Pneumonia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-31
Completion: 2026-12-31
Conditions
Critical Illness Pneumonia
Interventions
DRUG OTHER
No Results Yet
NCT06949475 | COMPLETED
60 Participants

Dual Task and Upper Extremity Performance in Children With Myelomeningocele

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-26
Completion: 2025-12-01
Conditions
Meningomyelocele
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06949410 | RECRUITING | PHASE1
36 Participants

HER2 Vaccine for Locally Advanced Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-03-31
Completion: 2029-12-31
Conditions
Breast Cancer HER2-positive Breast Cancer
Interventions
DRUG
No Results Yet
NCT06946524 | COMPLETED | PHASE1
59 Participants

A Study to Assess the Bioavailability of Risankizumab Following Subcutaneous Administration With Prefilled Pen Relative to a Prefilled Syringe in Healthy Adult Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-08
Completion: 2025-11-25
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06942442 | RECRUITING | PHASE2
47 Participants

A Phase II Trial of Tebentafusp in HLA-A*02:01 Positive Patients With Advanced Clear Cell Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-22
Completion: 2030-10-01
Conditions
HLA-A*0201 Positive Cells Present Clear Cell Sarcoma (CCS)
Interventions
DRUG
No Results Yet
NCT06942195 | RECRUITING | NA
8 Participants

Effects of Calcium on Gut Functions and Blood Glucose in Humans With Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-22
Completion: 2026-03-28
Conditions
T2DM
Interventions
OTHER
No Results Yet
NCT06935357 | RECRUITING | PHASE3
454 Participants

A Study to Learn About the Effects of Felzartamab Infusions on Adults With Immunoglobulin A Nephropathy (IgAN)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-08
Completion: 2027-05-31
Conditions
Immunoglobulin A Nephropathy (IgAN)
Interventions
DRUG
No Results Yet
NCT06934889 | RECRUITING | PHASE1
60 Participants

Study of ABBV-637 or ABBV-155 With ERAS-801 for People With Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-07
Completion: 2028-04-30
Conditions
Glioblastoma Gliosarcoma
Interventions
DRUG RADIATION
No Results Yet
NCT06934382 | RECRUITING | PHASE1
33 Participants

Anti-CD7 CAR-T Cells in Relapsed/Refractory T-Cell Acute Lymphoblastic Leukemia or Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-29
Completion: 2029-05-30
Conditions
T-Cell Acute Lymphoblastic Leukemia/Lymphoma
Interventions
BIOLOGICAL
No Results Yet
NCT06933043 | COMPLETED | PHASE1
24 Participants

A Study on the Safety, Tolerability, Bioavailability and Mechanism of Action of Intravenous NAV-240 in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-20
Completion: 2025-11-20
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
NCT06932666 | RECRUITING | NA
60 Participants

Why Calories Are Not the Same - a Gut Explanation?

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-15
Completion: 2026-12-31
Conditions
Diet, Healthy Breath Analysis
Interventions
OTHER
No Results Yet
NCT06930625 | RECRUITING | PHASE3
119 Participants

A Study to Assess the Efficacy and Safety of Debio 4126 in Participants With Acromegaly Previously Treated With Somatostatin Analogs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-26
Completion: 2028-06-30
Conditions
Acromegaly
Interventions
DRUG
No Results Yet
NCT06924970 | RECRUITING | PHASE2
56 Participants

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-01
Completion: 2026-05-31
Conditions
Sickle Cell Disease
Interventions
DRUG
No Results Yet
NCT06903104 | COMPLETED | NA
20 Participants

Acceptability and Feasibility of a Stress Prevention Program Based on Meditation and Acceptance and Commitment Therapy for Staff at a Cancer Center

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-13
Completion: 2025-04-30
Conditions
Employees at a Hospital
Interventions
OTHER DIAGNOSTIC_TEST
No Results Yet
NCT06896916 | RECRUITING | PHASE1
135 Participants

Study of Intravenously (IV) Infused Etentamig in Combination With an Oral Cereblon E3 Ligase Modulatory Drug (CELMoD) Agent Assessing Adverse Events and Change in Disease Activity in Adult Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-07
Completion: 2036-03-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06896240 | NOT_YET_RECRUITING | NA
24 Participants

Fiber Smoothie Supplement

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-31
Completion: 2027-01-01
Conditions
Total Knee Arthroplasty Revision Inflammatory Markers Gut Microbiota
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06893198 | ENROLLING_BY_INVITATION | NA
700 Participants

Conquering Hypertension in Urban Vietnam

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-01
Completion: 2029-02-28
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06892288 | RECRUITING | PHASE2/PHASE3
50 Participants

A Study to Assess the Efficacy and Safety of Weekly Doses of GLM101 in Participants With PMM2-CDG

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-07-09
Completion: 2026-01-31
Conditions
Phosphomannomutase 2 Deficiency PMM2-CDG
Interventions
DRUG
No Results Yet
NCT06888193 | RECRUITING | PHASE1
20 Participants

A Study to Assess the Concentration of Bimekizumab in Mature Breast Milk From Mothers Receiving Treatment With Bimzelx® (Bimekizumab)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-11-05
Completion: 2027-05-03
Conditions
Moderate to Severe Plaque Psoriasis Psoriatic Arthritis Axial Spondyloarthritis Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06878989 | RECRUITING | NA
30 Participants

Adaptation of Human Brown Adipose Tissue to Calorie Restriction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-01-25
Completion: 2025-12-31
Conditions
Obesity and Overweight
Interventions
BEHAVIORAL
No Results Yet
NCT06869018 | ACTIVE_NOT_RECRUITING | PHASE1
90 Participants

A Study of LY3549492 in Japanese Participants With Type 2 Diabetes Mellitus (T2D) and Healthy Japanese Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-05-07
Completion: 2026-02-28
Conditions
Healthy Type 2 Diabetes Mellitus (T2D)
Interventions
DRUG
No Results Yet
NCT06865482 | RECRUITING
65 Participants

Clinical Course Of Disease In Participants With FA-CM

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-09-30
Completion: 2027-09-30
Conditions
Friedreich Ataxia Cardiomyopathy
No Results Yet
NCT06863142 | RECRUITING | PHASE1
45 Participants

Evaluating the Dose, Safety, Tolerability, and Immunogenicity of Mosaic Hexavalent Influenza Vaccine VRCFLUMOS0116-00-VP (FluMos-v2) With and Without ALFQ Adjuvant in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-28
Completion: 2026-07-31
Conditions
Influenza Prevention Seasonal Influenza
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06861452 | RECRUITING | PHASE1/PHASE2
9 Participants

Phase I/IIa Study: RR001 Administered Following Chemotherapy Cycles for Patients With Locally Advanced Pancreatic Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-06-25
Completion: 2026-07-29
Conditions
Locally Advanced Pancreatic Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06859788 | RECRUITING | PHASE3
200 Participants

SPI-1005 for the Treatment of Meniere's Disease (Open Label)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-29
Completion: 2026-12-31
Conditions
Meniere's Disease Ménière's Disease
Interventions
DRUG
No Results Yet
NCT06859099 | ENROLLING_BY_INVITATION | PHASE3
300 Participants

Long-term Safety and Efficacy Study of Riliprubart in Participants With CIDP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-01
Completion: 2029-10-03
Conditions
Polyneuropathy, Inflammatory Demyelinating, Chronic
Interventions
DRUG
No Results Yet
NCT06853665 | NOT_YET_RECRUITING | PHASE4
196 Participants

The TEAM Study - Treatment Efficacy for Autism/Attention Using Mixed Amphetamine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-10
Completion: 2030-01-10
Conditions
Attention Deficit Hyperactivity Disorder (ADHD) Autism Autism Spectrum Disorder
Interventions
DRUG
No Results Yet
NCT06846320 | RECRUITING | PHASE2
315 Participants

Study to Assess Adverse Events and Change in Disease Activity When Oral ABBV-932 is Added to Antidepressant Therapies in Adult Participants With Generalized Anxiety Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-29
Completion: 2026-11-30
Conditions
Generalized Anxiety Disorder (GAD)
Interventions
DRUG
No Results Yet
NCT06838871 | COMPLETED | NA
20 Participants

Effects of Inspiratory Muscle Training and Abdominal Drawing-In Maneuver on Balance, Gait and Pulmonary Function in Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-24
Completion: 2025-04-25
Conditions
Subacute Stroke Balance Deficits
Interventions
BEHAVIORAL
No Results Yet
NCT06835296 | COMPLETED | PHASE1
47 Participants

A Study of Oral YUQ-A1007 in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-20
Completion: 2025-09-30
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT06828380 | RECRUITING | PHASE2
128 Participants

A Study Comparing Immunotherapy Alone Versus Immunotherapy Combined With Radiotherapy in Patients With Hepatocellular Carcinoma (HCC) With Vascular Invasion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-04-15
Completion: 2028-08-06
Conditions
Advanced Hepatocellular Carcinoma (HCC)
Interventions
RADIATION
No Results Yet
NCT06828263 | RECRUITING
130 Participants

Prospective Evaluation of Imaging Response Biomarkers During [177Lu]Lu-PSMA in Metastatic Castration-resistant Prostate Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-01
Completion: 2043-06-30
Conditions
Prostate Cancer Metastatic Disease
No Results Yet
NCT06823271 | RECRUITING | NA
20 Participants

Haemodynamics and Ventricular Arrhythmias During Exercise in Patients With Arrhythmogenic Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-08-01
Completion: 2026-06-30
Conditions
Arrhythmias, Cardiac
Interventions
OTHER
No Results Yet
NCT06817889 | RECRUITING | PHASE2
60 Participants

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-23
Completion: 2027-11-30
Conditions
Hematopoietic and Lymphatic System Neoplasm Autoimmune Disease Respiratory Syncytial Virus Infection
Interventions
DRUG OTHER PROCEDURE
No Results Yet
NCT06816524 | NOT_YET_RECRUITING | NA
324 Participants

The Effects of Iron Treatment on Malaria and Measles Vaccine Response in Kenyan Infants With Iron Deficiency

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-01-05
Completion: 2027-12-31
Conditions
Iron Deficiencies
Interventions
DIETARY_SUPPLEMENT BIOLOGICAL
No Results Yet
NCT06803875 | RECRUITING | PHASE1/PHASE2
42 Participants

Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-01-31
Completion: 2027-12-31
Conditions
Relapsed Neuroblastoma Refractory Neuroblastoma High-risk Neuroblastoma
Interventions
BIOLOGICAL
No Results Yet
NCT06801015 | ACTIVE_NOT_RECRUITING | PHASE4
30 Participants

Effects of Long-Acting GLP-1 (Glucagon-like Peptide-1) or Dual Incretin (GLP-1 and GIP [Glucose-dependent Insulinotropic Peptide]) Modulation on Gastric Motor Functions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-10-01
Completion: 2028-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06789445 | RECRUITING | PHASE1/PHASE2
54 Participants

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-03-10
Completion: 2029-10-31
Conditions
Primary Photoreceptor Disease Retinitis Pigmentosa (RP) Usher Syndrome Cone-Rod Dystrophy Inherited Retinal Disease (IRD) Rod-Cone Dystrophy Rod-Cone Disease Cone-Rod Disease Retinal Degeneration
Interventions
BIOLOGICAL
No Results Yet
NCT06774924 | RECRUITING | NA
100 Participants

"Clinical Ultrasound, a New Link Between Town and Hospital in Seine-Saint-Denis". (ECHO93)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-02-12
Completion: 2026-09-30
Conditions
Diagnosis Clinical Ultrasound
Interventions
DEVICE
No Results Yet
NCT06773104 | COMPLETED | NA
24 Participants

Autogenous Tooth Bone Graft Versus Allogeneic Bone Graft Around Dental Implant in Aesthetic Zone

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-03-25
Completion: 2025-01-16
Conditions
Immediate Dental Implants Thin Labial Plate of Bone Pre-extraction Hopeless Tooth in Esthetic Zone
Interventions
PROCEDURE
No Results Yet
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