Clinical Trials
Showing trials with last updates posted in 2025.
841
Participants
A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-04-29
Completion:
2024-11-01
Conditions
Respiratory Syncytial Virus Infections
Interventions
BIOLOGICAL
200
Participants
Nutritional Status Assessment and Dietary Recommendations Program (VENREDI)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-11-02
Completion:
2026-06-30
Conditions
Adherence to the Mediterranean Diet
Interventions
OTHER
No Results Yet
200
Participants
Real-World Treatment Study of Koselugo (Selumetinib)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2024-06-15
Completion:
2031-09-30
Conditions
Neurofibromatosis 1
Neurofibroma, Plexiform
No Results Yet
132
Participants
Combination of Immune Checkpoint in Locally Advanced or Metastatic MSI/dMMR Esogastric Adenocarcinomas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-08
Completion:
2028-05-15
Conditions
Gastric Cancer
MSI-H
Metastatic Cancer
Advanced Cancer
Interventions
DRUG
No Results Yet
110
Participants
Crohn's Disease: Efficacy, Safety, and Pharmacokinetics of Upadacitinib in Pediatric Subjects With Moderately to Severely Active Crohn's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-07-26
Completion:
2027-06-30
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
20
Participants
Hypofractionated Radiochemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-26
Completion:
2026-07-01
Conditions
Uterine Cervix Cancer
Interventions
DRUG
RADIATION
No Results Yet
18
Participants
Phase 2 Ascending Dose Safety and Efficacy Study of RVP-001, a Manganese-based MRI Contrast Agent
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-08-15
Completion:
2025-12-19
Conditions
Neoplasia
Central Nervous System (CNS) Lesions
Brain Metastases
Brain Neoplasms
Brain Neoplasms, Benign
Brain Tumor, Primary
Brain Tumor, Recurrent
Brain Tumors
Brain Cancer
Brain Tumor
Brain Neoplasm, Primary
Multiple Sclerosis
Multiple Sclerosis Brain Lesion
Neurofibroma
Acoustic Neuroma
CNS Tumor
CNS Lesion
CNS Metastases
CNS Cancer
CNS Lymphoma
Von Hippel Lindau
Meningioma
Glioma
Schwannomas
Neuroinflammation
Interventions
DRUG
No Results Yet
20
Participants
REPotrectinib in ROS1-positive Non-small Cell Lung Cancer Patients With Active Brain mEtastasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-06-27
Completion:
2027-03-31
Conditions
NSCLC
Brain Metastases
ROS1 Gene Rearrangement
Interventions
DRUG
No Results Yet
100
Participants
Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-05-17
Completion:
2029-05-01
Conditions
Sickle Cell Disease
Thalassemia
Hemoglobinopathy
Interventions
BIOLOGICAL
No Results Yet
30
Participants
Sleep Health Enhancement in Midlife Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-02-13
Completion:
2025-11-19
Conditions
Sleep Health
Midlife Adults
Interventions
BEHAVIORAL
No Results Yet
2610
Participants
A Non-interventional Study for Women With HR-positive, HER2-negative Locally Advanced or Metastatic Breast Cancer to Evaluate the Real-world Effectiveness of Treatment Algorithms Beginning With Ribociclib + AI/FUL, or With Endocrine Therapy or Chemotherapy as First Line Treatment
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2017-10-09
Completion:
2025-02-16
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
90
Participants
Exploring PTSD Symptoms, Barriers and Facilitators to Mindfulness
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-12-30
Completion:
2026-01-26
Conditions
Stress
Trauma
PTSD
HPA
Interventions
BEHAVIORAL
No Results Yet
43
Participants
Nurse-led Mind-body Intervention on Sexual Health for Breast Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-10-15
Completion:
2025-11-30
Conditions
Women's Health: Neoplasm of Breast
Menopause, Premature
Body Image
Sexual Dysfunction
Cancer, Breast
Interventions
BEHAVIORAL
No Results Yet
40
Participants
A Study of Mitapivat in Participants With Sickle Cell Disease and Nephropathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-03-31
Completion:
2027-05-31
Conditions
Sickle Cell Disease
Nephropathy
Interventions
DRUG
No Results Yet
40
Participants
Ibrutinib for the Prevention of Chronic Graft-Versus-Host Disease in Patients Undergoing Donor Stem Cell Transplant
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-12-13
Completion:
2027-06-30
Conditions
Chronic Graft Versus Host Disease
Hematopoietic and Lymphatic System Neoplasm
Interventions
PROCEDURE
DRUG
No Results Yet
48
Participants
Temporally-Resolved Electrophysiology of Acamprosate Treatment of Alcohol Use Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-05-07
Completion:
2025-12-31
Conditions
Alcohol Use Disorder
Interventions
DRUG
OTHER
No Results Yet
75
Participants
Sequencing Antibody Drug Conjugates in ER+/HER2 LOW/ULTRA LOW MBC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-06-17
Completion:
2026-06-30
Conditions
Advanced Breast Cancer
Metastatic Breast Cancer
Breast Cancer
Hormone-receptor-positive Breast Cancer
Human Epidermal Growth Factor 2 Low Breast Cancer
Interventions
DRUG
No Results Yet
19
Participants
Evaluation of CYT-108, A Recombinant Protease Inhibitor, for Treatment of Mild To Moderate Primary Osteoarthritis Of The Knee
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-06-01
Completion:
2025-03-15
Conditions
Osteoarthritis, Knee
Osteoarthritis
Interventions
BIOLOGICAL
OTHER
No Results Yet
4490
Participants
Observational Study Protocol: LIVER-R
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2023-03-16
Completion:
2030-12-30
Conditions
Hepatobiliary Cancers
Interventions
OTHER
No Results Yet
1300
Participants
Study of Oral Atogepant Tablets to Assess Safety and Efficacy in Adult Participants With Migraine
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-03-25
Completion:
2025-07-07
Conditions
Migraine
Interventions
DRUG
No Results Yet
12
Participants
KeyScope Study in Uganda
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2026-04-01
Completion:
2027-03-30
Conditions
Abdominal Neoplasm
Interventions
DEVICE
No Results Yet
195
Participants
The REBALANCE Study - a Prospective, Multicenter, Randomized, Pivotal Study of the May Health System
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-03-25
Completion:
2026-06-30
Conditions
Polycystic Ovary Syndrome
Infertility, Female
Interventions
DEVICE
No Results Yet
680
Participants
A Research Study Looking Into How Ziltivekimab Works Compared to Placebo in Participants With Heart Failure and Inflammation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-04-01
Completion:
2026-10-05
Conditions
Heart Failure
Systemic Inflammation
Interventions
DRUG
No Results Yet
11
Participants
Erector Spinae Plane (ESP) Block in Juvenile Idiopathic Scoliosis Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-09-11
Completion:
2024-12-11
Conditions
Juvenile Idiopathic Scoliosis, Multiple Sites in Spine
Interventions
PROCEDURE
No Results Yet
200
Participants
Lithium Versus Lamotrigine in Bipolar Disorder, Type II
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-05-08
Completion:
2027-12-01
Conditions
Bipolar II Disorder
Interventions
DRUG
No Results Yet
30
Participants
Alteplase Through an Indwelling Pleural Catheter for the Management of Symptomatic Septated Malignant Pleural Effusion
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-08-17
Completion:
2027-02-02
Conditions
Hematopoietic and Lymphoid Cell Neoplasm
Malignant Solid Neoplasm
Interventions
BIOLOGICAL
DRUG
No Results Yet
280
Participants
A Study to Evaluate the Efficacy and Safety of Faricimab in Patients With Choroidal Neovascularization Secondary to Pathologic Myopia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-03-06
Completion:
2025-09-11
Conditions
Choroidal Neovascularization Secondary to Pathologic Myopia
Interventions
DRUG
PROCEDURE
No Results Yet
60
Participants
PPOS (Progestin Primed Ovarian Stimulation) and Corifollitropin Alfa (CFA) Cross-over Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2025-01-27
Completion:
2027-12-31
Conditions
Ovarian Stimulation
Quality of Life
Preimplantation Genetic Testing
Fertility Preservation
Interventions
DRUG
No Results Yet
184
Participants
Heart Lung Machine Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2023-12-21
Completion:
2025-04-30
Conditions
Cardiac Surgery
Thoracic Surgery
Vascular Surgery
Cardiopulmonary Bypass
No Results Yet
3000
Participants
An Observational Study to Learn More About the Use of Vericiguat in Korean People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in Real-world Setting
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2023-11-30
Completion:
2027-03-31
Conditions
Chronic Heart Failure With Reduced Ejection Fraction
Interventions
DRUG
No Results Yet
30
Participants
PRP and PBD-VSEL Stem Cell Therapy for Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2019-09-10
Completion:
2022-09-15
Conditions
Regenerative Medicine
Interventions
BIOLOGICAL
No Results Yet
56
Participants
A Study to Assess the Efficacy, Safety, and Pharmacokinetics of Debio 4326 in Pediatric Participants With Central Precocious Puberty (LIBELULA™ Clinical Trial)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-07-31
Completion:
2026-10-31
Conditions
Central Precocious Puberty
Interventions
DRUG
No Results Yet
20
Participants
Telavancin Blood and Cerebrospinal Fluid Concentrations in Patients With External Ventricular Drainage
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-07-02
Completion:
2026-12-31
Conditions
Subarachnoid Hemorrhage, Aneurysmal
Interventions
DRUG
No Results Yet
50
Participants
Placental Learning Model for Neurovascular Microsurgery for the Management of Intracranial Aneurysms
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2020-07-16
Completion:
2028-02-29
Conditions
Intracranial Aneurysm
No Results Yet
46
Participants
Study to Assess the Safety, Tolerability, PK and PD of ABX1100
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-10-19
Completion:
2026-02-28
Conditions
Healthy
Late Onset Pompe Disease
Interventions
DRUG
No Results Yet
60
Participants
18F-Fluciclovine PET/CT in Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-03-25
Completion:
2026-12-06
Conditions
Multiple Myeloma
Newly Diagnosed Multiple Myeloma (NDMM)
Relapsed and/or Refractory Multiple Myeloma (RRMM)
Interventions
DRUG
PROCEDURE
No Results Yet
75
Participants
Imatinib to Increase RUNX1 Activity in Participants With Germline RUNX1 Deficiency
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-12-19
Completion:
2026-10-30
Conditions
Inherited Bone Marrow Failure Syndrome
Familial Platelet Disorder With Predisposition to Myeloid Malignancies
Interventions
DRUG
DEVICE
No Results Yet
500
Participants
Evaluation of Anti-PD-1 Therapy by Monitoring T Cell Responses in Melanoma, Lung and Other Cancer Types
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2015-06-15
Completion:
2026-12-31
Conditions
Clinical Stage III Cutaneous Melanoma AJCC v8
Clinical Stage IV Cutaneous Melanoma AJCC v8
Locally Advanced Lung Carcinoma
Locally Advanced Malignant Solid Neoplasm
Locally Advanced Melanoma
Metastatic Lung Carcinoma
Metastatic Malignant Solid Neoplasm
Metastatic Melanoma
Stage III Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
PROCEDURE
OTHER
No Results Yet
6
Participants
Molecular Signatures of Esophageal Atresia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2023-09-01
Completion:
2024-03-04
Conditions
Esophageal Atresia
Interventions
PROCEDURE
No Results Yet
200
Participants
Impact of Family-Centered Care for Intimate Partner Violence (IPV)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2024-01-10
Completion:
2026-02-15
Conditions
Intimate Partner Violence
Interventions
BEHAVIORAL
No Results Yet
Showing 40 trials per page