Clinical Trials

NCT05764265 | TERMINATED | PHASE2
31 Participants

Extension Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-27
Completion: 2024-04-26
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
NCT05760014 | COMPLETED
24 Participants

Medical Hypnosis and Stress Reduction in Hospitalization

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-28
Completion: 2024-02-09
Conditions
Stress
No Results Yet
NCT05758987 | RECRUITING | NA
160 Participants

Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-10
Completion: 2026-10-10
Conditions
PTSD CBT
Interventions
BEHAVIORAL
No Results Yet
NCT05756829 | RECRUITING | NA
580 Participants

Type 1 Diabetes Virtual Self-management Education and Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-10
Completion: 2026-12-31
Conditions
type1diabetes
Interventions
OTHER
No Results Yet
NCT05749679 | NOT_YET_RECRUITING | NA
360 Participants

Prevention of Renal Failure in People Followed for Type 2 Diabetes in General Practice

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-07-31
Completion: 2027-05-31
Conditions
Renal Insufficiency and Diabetes Mellitus
Interventions
OTHER
No Results Yet
NCT05741424 | COMPLETED | NA
100 Participants

Impact of BacT/Alert® VIRTUO®, BioFire® Blood Culture Identification 2-BCID2 and REVEAL® (bioMérieux) on the Optimization of Antibiotic Therapy for Gram-negative Bacteremia in the ICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-08
Completion: 2024-05-06
Conditions
Bacteremia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05728502 | RECRUITING
2400 Participants

An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-25
Completion: 2025-10-29
Conditions
Chronic Heart Failure With Reduced Ejection Fraction
Interventions
DRUG
No Results Yet
NCT05728333 | RECRUITING | PHASE2/PHASE3
800 Participants

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-28
Completion: 2026-02-28
Conditions
Stroke, Acute Ischemic
Interventions
DRUG
No Results Yet
NCT05724108 | ACTIVE_NOT_RECRUITING | PHASE2
94 Participants

Testing the Effectiveness of an Anti-cancer Drug, Triapine, When Used With Targeted Radiation-based Treatment (Lutetium Lu 177 Dotatate), Compared to Lutetium Lu 177 Dotatate Alone for Metastatic Neuroendocrine Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-30
Completion: 2026-12-09
Conditions
Metastatic Neuroendocrine Tumor
Interventions
PROCEDURE DRUG
No Results Yet
NCT05722210 | NOT_YET_RECRUITING
500 Participants

Prevalence and Development of Liver Dysfunction in Hematopoietic Stem Cell Transplant

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2031-06-30
Conditions
Hematopoietic Stem Cell Transplant
No Results Yet
NCT05714644 | COMPLETED | NA
5127 Participants

Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-07
Completion: 2024-06-30
Conditions
Colorectal Cancer
Interventions
OTHER
NCT05713799 | NOT_YET_RECRUITING | PHASE2
60 Participants

Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2030-03-01
Conditions
Insulin Resistance Obesity
Interventions
DRUG
No Results Yet
NCT05711615 | RECRUITING | PHASE1
30 Participants

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-02-06
Completion: 2026-05-03
Conditions
Metastatic Dedifferentiated Liposarcoma Metastatic Leiomyosarcoma Metastatic Myxofibrosarcoma Metastatic Sarcoma Metastatic Synovial Sarcoma Metastatic Undifferentiated Pleomorphic Sarcoma Unresectable Dedifferentiated Liposarcoma Unresectable Leiomyosarcoma Unresectable Myxofibrosarcoma Unresectable Sarcoma Unresectable Synovial Sarcoma Unresectable Undifferentiated Pleomorphic Sarcoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05704283 | RECRUITING | EARLY_PHASE1
55 Participants

3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-02-14
Completion: 2027-06-01
Conditions
Breast Carcinoma
Interventions
DEVICE
No Results Yet
NCT05691504 | RECRUITING | PHASE1
42 Participants

Testing the Combination of APG-1252 (Pelcitoclax) and Cobimetinib in Recurrent Ovarian and Endometrial Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-14
Completion: 2027-02-01
Conditions
Advanced Endometrial Carcinoma Metastatic Endometrial Carcinoma Metastatic Fallopian Tube Carcinoma Metastatic Platinum-Resistant Ovarian Carcinoma Metastatic Primary Peritoneal Carcinoma Recurrent Endometrial Carcinoma Recurrent Fallopian Tube Carcinoma Recurrent Platinum-Resistant Ovarian Carcinoma Recurrent Primary Peritoneal Carcinoma Stage III Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8 Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
Interventions
PROCEDURE DRUG
No Results Yet
NCT05691478 | RECRUITING | PHASE2/PHASE3
1122 Participants

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-03
Completion: 2030-03-20
Conditions
High Grade Osteosarcoma Localized Osteosarcoma Metastatic Osteosarcoma Secondary Osteosarcoma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05688410 | ACTIVE_NOT_RECRUITING | NA
198 Participants

Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-02-10
Completion: 2025-11-30
Conditions
Opioid Use Disorder Pain
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT05687669 | COMPLETED | PHASE4
170 Participants

Comparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-12
Completion: 2023-04-12
Conditions
Pre-Eclampsia; Complicating Pregnancy Pre-eclampsia Aggravated
Interventions
DRUG
No Results Yet
NCT05687149 | RECRUITING
200 Participants

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-23
Completion: 2035-12-31
Conditions
Fanconi Anemia Inherited Bone Marrow Failure Syndrome
No Results Yet
NCT05687110 | RECRUITING | PHASE1
43 Participants

Studying the Safety and Determining the Optimal Dose of Novobiocin in Patients With Tumors That Have Alterations in DNA Repair Genes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-06
Completion: 2026-08-01
Conditions
Metastatic Malignant Solid Neoplasm Unresectable Malignant Solid Neoplasm
Interventions
PROCEDURE BIOLOGICAL
No Results Yet
NCT05676320 | ACTIVE_NOT_RECRUITING | NA
203 Participants

Investigating Bone Cement With or Without Inossia® Cement Softener for Vertebral Compression Fractures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-03-11
Completion: 2025-10-20
Conditions
Vertebral Compression Fracture
Interventions
DEVICE
No Results Yet
NCT05675410 | RECRUITING | PHASE3
1875 Participants

A Study to Compare Standard Therapy to Treat Hodgkin Lymphoma to the Use of Two Drugs, Brentuximab Vedotin and Nivolumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-11
Completion: 2031-04-28
Conditions
Lugano Classification Limited Stage Hodgkin Lymphoma AJCC v8
Interventions
PROCEDURE BIOLOGICAL DRUG OTHER RADIATION
No Results Yet
NCT05671471 | COMPLETED
147 Participants

Accidental Reactions in Peanut/Tree Nut Allergic Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-09-22
Completion: 2022-10-10
Conditions
Peanut and Tree Nut Allergy
No Results Yet
NCT05671328 | COMPLETED
263 Participants

Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-28
Completion: 2025-07-18
Conditions
Ventilator Associated Pneumonia Pulmonary Aspergillosis Invasive
Interventions
OTHER
No Results Yet
NCT05666518 | RECRUITING
1400 Participants

A Study to Learn More About the Safety of the Drug Vericiguat in Japanese People With Chronic Heart Failure Who Will be Receiving Vericiguat Under Real-world Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-31
Completion: 2027-12-31
Conditions
Chronic Heart Failure
Interventions
DRUG
No Results Yet
NCT05662423 | RECRUITING | NA
136 Participants

Preventing Childbirth-Related PTSD With Expressive Writing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-08
Completion: 2026-01-31
Conditions
PTSD (Childbirth-Related)
Interventions
BEHAVIORAL
No Results Yet
NCT05657405 | RECRUITING
1250 Participants

Observational Study of Advanced Data Analytics in Genetic Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2032-12-31
Conditions
Genetic Conditions
No Results Yet
NCT05656378 | RECRUITING
600 Participants

A Repository to Study Host-Microbiome Interactions in Health and Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-09
Completion: 2032-01-01
Conditions
Healthy Controls Pregnancy Pediatric Illnesses Inflammatory Diseases
No Results Yet
NCT05653388 | RECRUITING
200 Participants

Metastatic Leiomyosarcoma Biomarker Protocol

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-12-22
Completion: 2026-12-31
Conditions
Leiomyosarcoma
Interventions
OTHER
No Results Yet
NCT05652504 | SUSPENDED | PHASE1
400 Participants

Safety Evaluation of PfSPZ Vaccine in Pregnant Women in Mali (MalVIP1)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-11-30
Conditions
Malaria
Interventions
BIOLOGICAL OTHER DRUG
No Results Yet
NCT05652478 | RECRUITING | PHASE2
120 Participants

Early Metabolic Effects of Dolutegravir or Tenofovir Alefenamide in Healthy Volunteers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2028-01-31
Conditions
Metabolic Effects Weight Gain Healthy Volunteer Integrase Strand Transfer Inhibitors
Interventions
DRUG
No Results Yet
NCT05652465 | SUSPENDED | PHASE2
80 Participants

Transcranial Magnetic Stimulation for Youth With Treatment-Resistant Major Depressive Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-01-30
Conditions
Major Depressive Disorder
Interventions
DEVICE
No Results Yet
NCT05642195 | SUSPENDED | PHASE1/PHASE2
30 Participants

Evaluation of a Cancer Lysate Vaccine and Montanide (Registered Trademark) ISA-51 VG With or Without the IL-15 Super-Agonist N-803 as Adjuvant Therapy for PD-L1 Negative Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2033-12-30
Conditions
Non-Small Cell Lung Cancer Non-Small Cell Lung Carcinoma Carcinoma, Non-Small-Cell Lung Carcinomas
Interventions
BIOLOGICAL DRUG DEVICE
No Results Yet
NCT05638295 | RECRUITING | PHASE2
105 Participants

Testing the Use of AMG 510 (Sotorasib) and Panitumumab as a Targeted Treatment for KRAS G12C Mutant Solid Tumor Cancers (A ComboMATCH Treatment Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-08-01
Completion: 2028-12-31
Conditions
Advanced Malignant Solid Neoplasm Metastatic Malignant Solid Neoplasm
Interventions
PROCEDURE BIOLOGICAL DRUG
No Results Yet
NCT05635929 | COMPLETED | NA
63 Participants

Effect of a Novel Topical Composition (XCM-0M118) on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-10-11
Completion: 2023-06-28
Conditions
Oral Mucositis Quality of Life Mucositis Pain Speech Saliva Radiation Toxicity Chemotherapeutic Toxicity Head and Neck Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05621291 | RECRUITING | NA
60 Participants

A Study to Evaluate Next-Generation Sequencing (NGS) Testing and Monitoring of B-cell Recovery to Guide Management Following Chimeric Antigen Receptor T-cell (CART) Induced Remission in Children and Young Adults With B Lineage Acute Lymphoblastic Leu...

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2025-12-30
Completion: 2026-12-31
Conditions
B-All Acute Lymphoblastic Leukemia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05618158 | COMPLETED | NA
1796 Participants

Cancer Prevention for Young Rural Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-04-20
Completion: 2025-08-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05616650 | RECRUITING | PHASE2
42 Participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-10-19
Completion: 2027-12-01
Conditions
Prostatic Neoplasms Prostate Cancer Prostate Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05616130 | RECRUITING
255 Participants

Pathological Myeloid Activation After Sepsis and Trauma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-01
Completion: 2027-09-01
Conditions
Trauma Injury Sepsis Immunosuppression Chronic Critical Illness
Interventions
OTHER PROCEDURE
No Results Yet
NCT05600894 | ACTIVE_NOT_RECRUITING | PHASE2
132 Participants

Venetoclax in Combination With ASTX727 for the Treatment of Chronic Myelomonocytic Leukemia and Other Myelodysplastic Syndrome/Myeloproliferative Neoplasm

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-27
Completion: 2026-08-31
Conditions
Chronic Myelomonocytic Leukemia Myelodysplastic Syndrome Myelodysplastic Syndrome With Excess Blasts Myelodysplastic/Myeloproliferative Neoplasm Myeloproliferative Neoplasm
Interventions
PROCEDURE DRUG
No Results Yet
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