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Clinical Trials

Showing trials with last updates posted in 2025.

NCT05782907 | ACTIVE_NOT_RECRUITING | PHASE3
122 Participants

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-06
Completion: 2028-08-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT05779462 | RECRUITING
52 Participants

ENDOMETRIOSIS - MRI

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-23
Completion: 2026-07-31
Conditions
Endometriosis Mobility Limitation Magnetic Resonance Imaging Diagnosis Pelvis Comparative Study
Interventions
OTHER
No Results Yet
NCT05777993 | ENROLLING_BY_INVITATION | PHASE4
6 Participants

A Study to Provide Continued Access to Mitapivat for Participants Who Previously Completed an Agios-Sponsored Mitapivat Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-07-06
Completion: 2029-08-31
Conditions
Pyruvate Kinase Deficiency Anemia, Hemolytic
Interventions
DRUG
No Results Yet
NCT05774678 | RECRUITING | PHASE3
126 Participants

Trial Of PreoperAtive Radiation (TOPAz): A Randomized Trial Comparing Hypofractionated Versus Conventionally Fractionated Preoperative Radiation Followed by Mastectomy With Immediate Autologous Breast Reconstruction With Integrated Nanomechanical Biomarker Evaluation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-05
Completion: 2026-11-01
Conditions
Breast Cancer
Interventions
RADIATION OTHER
No Results Yet
NCT05774600 | COMPLETED | NA
641 Participants

Virtual Sun Safe Workplaces Ph II (SSW Works)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-01
Completion: 2025-02-25
Conditions
Skin Cancer Occupational Exposure
Interventions
BEHAVIORAL
No Results Yet
NCT05765812 | RECRUITING | PHASE1/PHASE2
116 Participants

A Study of Debio 0123 in Combination With Temozolomide in Adult Participants With Recurrent or Progressive Glioblastoma and of Debio 0123 in Combination With Temozolomide and Radiotherapy in Adult Participants With Newly Diagnosed Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-15
Completion: 2028-09-30
Conditions
Glioblastoma IDH (Isocitrate Dehydrogenase) Wildtype Astrocytoma, Grade III
Interventions
DRUG RADIATION
No Results Yet
NCT05764265 | TERMINATED | PHASE2
31 Participants

Extension Study of Efficacy and Safety of LTP001 in Pulmonary Arterial Hypertension Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-27
Completion: 2024-04-26
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
Results Available
NCT05760014 | COMPLETED
24 Participants

Medical Hypnosis and Stress Reduction in Hospitalization

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-28
Completion: 2024-02-09
Conditions
Stress
No Results Yet
NCT05758987 | RECRUITING | NA
160 Participants

Blended Treatment för PTSD: A New Format of Computer-Assisted Trauma-Focused Cognitive Behavioral Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-10
Completion: 2026-10-10
Conditions
PTSD CBT
Interventions
BEHAVIORAL
No Results Yet
NCT05756829 | RECRUITING | NA
580 Participants

Type 1 Diabetes Virtual Self-management Education and Support

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-05-10
Completion: 2026-12-31
Conditions
type1diabetes
Interventions
OTHER
No Results Yet
NCT05749679 | NOT_YET_RECRUITING | NA
360 Participants

Prevention of Renal Failure in People Followed for Type 2 Diabetes in General Practice

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-07-31
Completion: 2027-05-31
Conditions
Renal Insufficiency and Diabetes Mellitus
Interventions
OTHER
No Results Yet
NCT05741424 | COMPLETED | NA
100 Participants

Impact of BacT/Alert® VIRTUO®, BioFire® Blood Culture Identification 2-BCID2 and REVEAL® (bioMérieux) on the Optimization of Antibiotic Therapy for Gram-negative Bacteremia in the ICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-08
Completion: 2024-05-06
Conditions
Bacteremia
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05728502 | RECRUITING
2400 Participants

An Observational Study, Called VERI-China, to Learn More About How Well Vericiguat Works and How Safe it is in Real-world Setting in People With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) in China

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-25
Completion: 2025-10-29
Conditions
Chronic Heart Failure With Reduced Ejection Fraction
Interventions
DRUG
No Results Yet
NCT05728333 | RECRUITING | PHASE2/PHASE3
800 Participants

Intravenous Tirofiban Versus Alteplase Before Mechanical Thrombectomy in Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-28
Completion: 2026-02-28
Conditions
Stroke, Acute Ischemic
Interventions
DRUG
No Results Yet
NCT05714644 | COMPLETED | NA
5127 Participants

Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-07
Completion: 2024-06-30
Conditions
Colorectal Cancer
Interventions
OTHER
Results Available
NCT05704283 | RECRUITING | EARLY_PHASE1
55 Participants

3D Ultrasound for the Imaging of Lymph Nodes in Patients With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-02-14
Completion: 2027-06-01
Conditions
Breast Carcinoma
Interventions
DEVICE
No Results Yet
NCT05688410 | ACTIVE_NOT_RECRUITING | NA
198 Participants

Enhancing Exercise and Psychotherapy to Treat Pain and Addiction in Adults With an Opioid Use Disorder (EXPO; R33 Phase)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-02-10
Completion: 2025-11-30
Conditions
Opioid Use Disorder Pain
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT05687669 | COMPLETED | PHASE4
170 Participants

Comparison Between the Use of Phentolamine Versus Glyceryl Trinitrate for Their Effect on Renal Function in Pre-eclampsia Patients in ICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-01-12
Completion: 2023-04-12
Conditions
Pre-Eclampsia; Complicating Pregnancy Pre-eclampsia Aggravated
Interventions
DRUG
No Results Yet
NCT05687149 | RECRUITING
200 Participants

Defining the Natural History of Squamous Cell Carcinoma in Fanconi Anemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-23
Completion: 2035-12-31
Conditions
Fanconi Anemia Inherited Bone Marrow Failure Syndrome
No Results Yet
NCT05676320 | ACTIVE_NOT_RECRUITING | NA
203 Participants

Investigating Bone Cement With or Without Inossia® Cement Softener for Vertebral Compression Fractures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2021-03-11
Completion: 2025-10-20
Conditions
Vertebral Compression Fracture
Interventions
DEVICE
No Results Yet
NCT05671471 | COMPLETED
147 Participants

Accidental Reactions in Peanut/Tree Nut Allergic Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2021-09-22
Completion: 2022-10-10
Conditions
Peanut and Tree Nut Allergy
No Results Yet
NCT05671328 | COMPLETED
263 Participants

Incidence of Invasive Pulmonary Aspergillosis in Ventilator-associated Pneumonia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-08-28
Completion: 2025-07-18
Conditions
Ventilator Associated Pneumonia Pulmonary Aspergillosis Invasive
Interventions
OTHER
No Results Yet
NCT05666518 | RECRUITING
1400 Participants

A Study to Learn More About the Safety of the Drug Vericiguat in Japanese People With Chronic Heart Failure Who Will be Receiving Vericiguat Under Real-world Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-08-31
Completion: 2027-12-31
Conditions
Chronic Heart Failure
Interventions
DRUG
No Results Yet
NCT05662423 | RECRUITING | NA
136 Participants

Preventing Childbirth-Related PTSD With Expressive Writing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-11-08
Completion: 2026-01-31
Conditions
PTSD (Childbirth-Related)
Interventions
BEHAVIORAL
No Results Yet
NCT05656378 | RECRUITING
600 Participants

A Repository to Study Host-Microbiome Interactions in Health and Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-09
Completion: 2032-01-01
Conditions
Healthy Controls Pregnancy Pediatric Illnesses Inflammatory Diseases
No Results Yet
NCT05653388 | RECRUITING
200 Participants

Metastatic Leiomyosarcoma Biomarker Protocol

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-12-22
Completion: 2026-12-31
Conditions
Leiomyosarcoma
Interventions
OTHER
No Results Yet
NCT05635929 | COMPLETED | NA
63 Participants

Effect of a Novel Topical Composition (XCM-0M118) on the Incidence of Severe Oral Mucositis in Head & Neck Cancer Radiated Patients and Quality of Life Assessed by PROMs.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2022-10-11
Completion: 2023-06-28
Conditions
Oral Mucositis Quality of Life Mucositis Pain Speech Saliva Radiation Toxicity Chemotherapeutic Toxicity Head and Neck Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT05618158 | COMPLETED | NA
1796 Participants

Cancer Prevention for Young Rural Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2024-04-20
Completion: 2025-08-31
Conditions
Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT05616650 | RECRUITING | PHASE2
42 Participants

Focal Therapy With Stereotactic Body Radiation Therapy (SBRT) for Patients With a Single Prostate Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-10-19
Completion: 2027-12-01
Conditions
Prostatic Neoplasms Prostate Cancer Prostate Adenocarcinoma
Interventions
DRUG RADIATION
No Results Yet
NCT05616130 | RECRUITING
255 Participants

Pathological Myeloid Activation After Sepsis and Trauma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-09-01
Completion: 2027-09-01
Conditions
Trauma Injury Sepsis Immunosuppression Chronic Critical Illness
Interventions
OTHER PROCEDURE
No Results Yet
NCT05591521 | COMPLETED
206 Participants

Evaluation of Pain in the Course of in Vitro Fertilization: the Endalgofiv-2 Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-30
Completion: 2024-03-24
Conditions
Infertility
Interventions
OTHER
No Results Yet
NCT05588167 | RECRUITING
100 Participants

Establishment of Genomic and Phenotypic Database for Niemann-Pick Disease, Type C

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-11-28
Completion: 2026-09-30
Conditions
Niemann-Pick Disease, Type C
No Results Yet
NCT05581121 | RECRUITING | PHASE3
510 Participants

PARa-aOrtic LymphAdenectomy in Locally Advanced Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-20
Completion: 2031-12-31
Conditions
Cervical Carcinoma Adenocarcinoma Adenosquamous Carcinoma
Interventions
OTHER PROCEDURE
No Results Yet
NCT05577143 | RECRUITING
303 Participants

Blood Screening for Adult Colorectal Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-03-23
Completion: 2026-03-31
Conditions
Cancer Colorectal
No Results Yet
NCT05573893 | RECRUITING
800 Participants

PROVIDENCE - Prospective Non-interventional Study (NIS) to Examine Patient-reported Outcomes and Real-world Clinical Data in Patients With HER2-positive, HER2-low or HER2-ultralow Unresectable or Metastatic Breast Cancer Treated With Trastuzumab Deruxtecan

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2023-09-12
Completion: 2031-12-31
Conditions
Breast Neoplasms Breast Cancer Neoplasm Metastasis
No Results Yet
NCT05570851 | ENROLLING_BY_INVITATION | NA
138 Participants

Alcohol Cessation Among Head and Neck Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-01
Completion: 2026-03-31
Conditions
Head and Neck Cancer Alcohol Use, Unspecified
Interventions
BEHAVIORAL
No Results Yet
NCT05559671 | RECRUITING | PHASE4
224 Participants

Safety of the Herpes Zoster Subunit Vaccine in Lupus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-12-21
Completion: 2027-07-31
Conditions
Systemic Lupus Erythematosus
Interventions
BIOLOGICAL
No Results Yet
NCT05544019 | RECRUITING | PHASE1
52 Participants

Study of SGR-1505 in Mature B-Cell Neoplasms

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-04-10
Completion: 2026-03-31
Conditions
Mature B-Cell Neoplasm Non Hodgkin Lymphoma DLBCL Waldenstrom Macroglobulinemia MALT Lymphoma Follicular Lymphoma Pediatric-Type Follicular Lymphoma IRF4 Gene Rearrangement EBV-Positive DLBCL, Nos Burkitt Lymphoma Plasmablastic Lymphoma High-grade B-cell Lymphoma Primary Cutaneous Follicle Center Lymphoma Primary Effusion Lymphoma Mantle Cell Lymphoma DLBCL Germinal Center B-Cell Type Primary Mediastinal Large B Cell Lymphoma T-Cell/Histiocyte Rich Lymphoma ALK-Positive Large B-Cell Lymphoma Primary Cutaneous Diffuse Large B-Cell Lymphoma Splenic Marginal Zone Lymphoma Chronic Lymphocytic Leukemia Nodal Marginal Zone Lymphoma HHV8-Positive DLBCL, Nos Lymphoplasmacytic Lymphoma Duodenal-Type Follicular Lymphoma
Interventions
DRUG
No Results Yet
NCT05534399 | NOT_YET_RECRUITING | NA
526 Participants

Antibiotic Strategy and Asymptomatic Bacteriuria in the Context of Intra-vesical Botulinum Toxin A Injections.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-05-31
Completion: 2027-03-31
Conditions
Urinary Tract Disease
Interventions
PROCEDURE
No Results Yet
NCT05533645 | RECRUITING | NA
99 Participants

Food Frequency Questionnaire to Assess Sodium Intake

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2023-06-06
Completion: 2026-06-30
Conditions
Hypertension Renal Insufficiency
Interventions
OTHER
No Results Yet
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