Clinical Trials

NCT05413005 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1

10 Participants

Efficacy of Extracorporeal Photopheresis (ECP) in the Treatment of Type 1 Diabetes Mellitus

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-09-05

Completion: 2026-09-01

Conditions

Type 1 Diabetes

Interventions

BIOLOGICAL COMBINATION_PRODUCT

No Results Yet

NCT05411094 | RECRUITING | PHASE1

18 Participants

Testing the Safety of the Anti-Cancer Drugs Durvalumab and Olaparib During Radiation Therapy for Locally Advanced Unresectable Pancreatic Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-05-22

Completion: 2026-07-01

Conditions

Locally Advanced Pancreatic Carcinoma Stage II Pancreatic Cancer AJCC v8 Stage III Pancreatic Cancer AJCC v8 Unresectable Pancreatic Carcinoma

Interventions

PROCEDURE BIOLOGICAL DRUG

No Results Yet

NCT05411081 | RECRUITING | PHASE2

200 Participants

Testing Cabozantinib With or Without Atezolizumab in Patients With Advanced Papillary Kidney Cancer, PAPMET2 Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-03-24

Completion: 2027-07-01

Conditions

Metastatic Papillary Renal Cell Carcinoma Stage IV Renal Cell Cancer AJCC v8

Interventions

BIOLOGICAL PROCEDURE DRUG

No Results Yet

NCT05406037 | RECRUITING

100 Participants

Biomarkers for Invasive Mucormycosis

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-29

Completion: 2026-07-31

Conditions

Mucorales Infection Mucormycosis

Interventions

BIOLOGICAL

No Results Yet

NCT05405491 | ACTIVE_NOT_RECRUITING | NA

31 Participants

Impact of a Strategy Based on Bacterial DNA Detection to Optimize Antibiotics in Immunocompromised Patients With Hospital-acquired Pneumonia Requiring Mechanical Ventilation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-03-28

Completion: 2028-03-31

Conditions

Pneumonia, Ventilator-Associated Pneumonia, Hospital-Acquired Immunodeficiency

Interventions

OTHER

No Results Yet

NCT05403866 | COMPLETED | PHASE2

89 Participants

A Study to Evaluate the Safety and Efficacy of Multiple Doses of LT3001 Drug Product in AIS Subjects

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-17

Completion: 2025-05-23

Conditions

Acute Ischemic Stroke

Interventions

DRUG

Results Available

NCT05400603 | RECRUITING | PHASE1

24 Participants

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-11-06

Completion: 2026-12-31

Conditions

Neuroblastoma Refractory Neuroblastoma Relapsed Neuroblastoma Relapsed Osteosarcoma Refractory Osteosarcoma

Interventions

COMBINATION_PRODUCT

No Results Yet

NCT05392556 | COMPLETED | NA

73 Participants

Prebiotic and Probiotic Modulation of the Gut Microbiota-gut-brain Axis During Acute Stress

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-07-06

Completion: 2025-10-28

Conditions

Stress Physiology

Interventions

DIETARY_SUPPLEMENT OTHER

No Results Yet

NCT05375812 | RECRUITING

85 Participants

NIH Investigative Deep Phenotyping Study of Gulf War Veteran Health (Project NIH IN-DEPTH)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2023-04-16

Completion: 2030-12-31

Conditions

Gulf War Illness

No Results Yet

NCT05372627 | NOT_YET_RECRUITING

1000 Participants

NHLBI-Emory Advanced Cardiac CT Reconstruction

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2025-12-30

Completion: 2031-01-30

Conditions

Structural Heart Disease

No Results Yet

NCT05357742 | COMPLETED | NA

50 Participants

Basic Needs Navigation Intervention to Address Multidimensional Adversity in African Americans With Diabetic Kidney Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-01

Completion: 2025-07-31

Conditions

Diabetic Nephropathies Diabetes Mellitus, Type 2 Chronic Kidney Diseases Healthy Lifestyle

Interventions

BEHAVIORAL

No Results Yet

NCT05353439 | RECRUITING | PHASE1

60 Participants

Testing of Tazemetostat in Combination With Topotecan and Pembrolizumab in Patients With Recurrent Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-07-27

Completion: 2027-04-01

Conditions

Extensive Stage Lung Small Cell Carcinoma Limited Stage Lung Small Cell Carcinoma Platinum-Resistant Lung Small Cell Carcinoma Platinum-Sensitive Lung Small Cell Carcinoma Recurrent Extensive Stage Lung Small Cell Carcinoma Recurrent Lung Small Cell Carcinoma

Interventions

PROCEDURE BIOLOGICAL DRUG

No Results Yet

NCT05353153 | COMPLETED | NA

60 Participants

The Psychological Experience of Pathological Pregnancy. Study of the Case of Premature Rupture of Membranes and Evaluation of the Impact of Hypnosis Support

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-06-03

Completion: 2025-01-10

Conditions

Preterm Premature Rupture of Membrane

Interventions

OTHER

No Results Yet

NCT05348876 | RECRUITING | PHASE4

50 Participants

A Study to Learn More About How Safe Darolutamide is and How Well it Works Under Real World Conditions When Taken in Addition to Standard Androgen Deprivation Therapy (ADT) in Indian Participants With High-risk Non-metastatic Castration-resistant Prostate Cancer (nmCRPC)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-03

Completion: 2026-01-28

Conditions

Non-metastatic Castration-resistant Prostate Cancer

Interventions

DRUG

No Results Yet

NCT05333458 | RECRUITING | PHASE2

27 Participants

Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, The AXIOM Trial

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-29

Completion: 2027-05-01

Conditions

Advanced Alveolar Soft Part Sarcoma Advanced Soft Tissue Sarcoma Metastatic Alveolar Soft Part Sarcoma Refractory Alveolar Soft Part Sarcoma Unresectable Alveolar Soft Part Sarcoma

Interventions

BIOLOGICAL PROCEDURE DRUG

No Results Yet

NCT05327270 | ACTIVE_NOT_RECRUITING | PHASE1

18 Participants

Non-randomized, Open-label Study of Intralesional Nivolumab for High Risk Oral Premalignant Lesions

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-09-13

Completion: 2027-02-02

Conditions

Head and Neck Cancer

Interventions

DRUG

No Results Yet

NCT05324358 | COMPLETED | PHASE3

341 Participants

Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-12-14

Completion: 2024-09-06

Conditions

Pain, Postoperative

Interventions

DRUG OTHER

No Results Yet

NCT05304091 | WITHDRAWN

0 Participants

Characterization of Rhythmicity Profiles of Bradykinin-mediated Angioedema Attacks Using a Tracking Smartphone Application.

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-31

Completion: 2023-08-31

Conditions

Bradykinin-mediated Angioedema

Interventions

OTHER

No Results Yet

NCT05304065 | RECRUITING | PHASE2

1600 Participants

Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-10-17

Completion: 2026-12-31

Conditions

Suicide and Self-harm

Interventions

BEHAVIORAL

No Results Yet

NCT05303467 | RECRUITING | PHASE1

36 Participants

A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-07-30

Completion: 2026-03-31

Conditions

Glioblastoma Multiforme Recurrent Glioblastoma

Interventions

DEVICE

No Results Yet

NCT05295095 | RECRUITING | NA

264 Participants

Does Positive Pressure Extubation Reduce Postoperative Desaturation?

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-06-29

Completion: 2026-06-30

Conditions

Extubation Postoperative Complications Lung Ultrasound Score

Interventions

PROCEDURE

No Results Yet

NCT05281835 | RECRUITING

1000 Participants

Follow-up of Elderly Subjects With Falls Recruited in the Geriatric Departments of Several French Hospitals

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2022-06-16

Completion: 2026-03-31

Conditions

Falls in the Elderly

No Results Yet

NCT05279170 | RECRUITING | NA

72 Participants

MAsk VEntilation With Paratracheal Pressure In Children. Para Tracheal Compression to Prevent Gastric Insufflation in Children

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-06-06

Completion: 2027-06-30

Conditions

Surgery Anesthesia Intubation Complication

Interventions

OTHER

No Results Yet

NCT05278741 | ACTIVE_NOT_RECRUITING | NA

32 Participants

Functional Evaluation After Breast Reconstruction With a Minimally Invasive Latissimus Dorsi Flap Following Radical Surgery for Breast Cancer.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-11-25

Completion: 2026-03-06

Conditions

Breast Cancer

Interventions

PROCEDURE

No Results Yet

NCT05274022 | ACTIVE_NOT_RECRUITING | NA

66 Participants

Rehabilitation Strategies to Improve Outcomes For Patients With a Lower Extremity Fracture

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-03-03

Completion: 2026-02-01

Conditions

Femoral Fracture Tibial Fractures

Interventions

OTHER

No Results Yet

NCT05273138 | RECRUITING

40 Participants

Analysis of Dermal Fibroblasts and Immune Cells During Systemic Sclerosis

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2022-06-08

Completion: 2026-06-30

Conditions

Systemic Sclerosis

Interventions

OTHER

No Results Yet

NCT05273125 | RECRUITING

417 Participants

MOBility Disorders Assessment in Patients With Mild COGnitive Disorders

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2022-09-09

Completion: 2026-09-30

Conditions

Cognitive Dysfunction

Interventions

BEHAVIORAL

No Results Yet

NCT05256225 | RECRUITING | PHASE3

360 Participants

Testing the Addition of Herceptin Hylecta or Phesgo to the Usual Chemotherapy for HER2 Positive Endometrial Serous Carcinoma or Carcinosarcoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-11-16

Completion: 2027-10-31

Conditions

Endometrial Carcinoma Endometrial Clear Cell Adenocarcinoma Endometrial Dedifferentiated Carcinoma Endometrial Endometrioid Adenocarcinoma Endometrial Mixed Cell Adenocarcinoma Endometrial Serous Adenocarcinoma Endometrial Undifferentiated Carcinoma Uterine Corpus Carcinosarcoma

Interventions

PROCEDURE DRUG RADIATION OTHER

No Results Yet

NCT05233449 | COMPLETED | NA

30 Participants

NoL Index Response to Stimulation in Anesthetized Children

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-03-04

Completion: 2022-05-17

Conditions

Anesthesia

Interventions

DEVICE PROCEDURE

No Results Yet

NCT05230914 | RECRUITING | NA

1846 Participants

A Randomized Trial of Imaging Selection Modalities for Stroke Thrombectomy (NO-SELECT)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-12-12

Completion: 2027-06-30

Conditions

Stroke, Ischemic Stroke, Acute

Interventions

OTHER

No Results Yet

NCT05223036 | SUSPENDED | PHASE2

80 Participants

Testing Obeticholic Acid for Familial Adenomatous Polyposis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-01-19

Completion: 2029-01-31

Conditions

Attenuated Familial Adenomatous Polyposis Colorectal Carcinoma Duodenal Carcinoma Familial Adenomatous Polyposis

Interventions

PROCEDURE BIOLOGICAL DRUG OTHER

No Results Yet

NCT05198830 | RECRUITING | PHASE2

42 Participants

Testing the Addition of an Anti-Cancer Drug, TRC102, to the Usual Chemotherapy Treatment (Pemetrexed, Cisplatin or Carboplatin) During Radiation Therapy for Stage III Non-Squamous Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-12-15

Completion: 2027-06-30

Conditions

Lung Adenocarcinoma Lung Large Cell Carcinoma Lung Non-Squamous Non-Small Cell Carcinoma Stage III Lung Cancer AJCC v8

Interventions

DRUG PROCEDURE BIOLOGICAL RADIATION

No Results Yet

NCT05183048 | RECRUITING | EARLY_PHASE1

14 Participants

Comparison of 89Zr Panitumumab and (18)F-Fluorodeoxyglucose to Identify Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2023-02-20

Completion: 2028-02-29

Conditions

Head and Neck Squamous Cell Carcinoma

Interventions

DRUG

No Results Yet

NCT05161689 | COMPLETED | NA

636 Participants

Addressing the Continuum of Care Among High-risk Thai Men

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2021-11-27

Completion: 2024-12-10

Conditions

HIV/AIDS STD

Interventions

BEHAVIORAL

Results Available

NCT05144724 | COMPLETED | NA

52 Participants

Volume Targeted Mask Ventilation Versus Pressure Ventilation in Preterm Infants

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2024-10-01

Completion: 2025-10-30

Conditions

Neonatal Respiratory Distress

Interventions

PROCEDURE

No Results Yet

NCT05142293 | ACTIVE_NOT_RECRUITING

354 Participants

One Day Implantation Program for Heart Failure Patients Implanted With CRT-P

Study Type: OBSERVATIONAL

Last Updated: 2025-12-26

Start Date: 2021-12-06

Completion: 2026-01-31

Conditions

Heart Failure

Interventions

OTHER

No Results Yet

NCT05136664 | COMPLETED | PHASE3

262 Participants

Trial Evaluating the Efficacy and Safety of Patiromer in Chinese Subjects

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-02-10

Completion: 2025-11-18

Conditions

Hyperkalemia Renal Insufficiency, Chronic

Interventions

DRUG

No Results Yet

NCT05136196 | RECRUITING | PHASE2

150 Participants

BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-12-06

Completion: 2027-01-01

Conditions

Clinical Stage III Cutaneous Melanoma AJCC v8 Clinical Stage III HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Clinical Stage IV Cutaneous Melanoma AJCC v8 Clinical Stage IV HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma AJCC v8 Locally Recurrent Head and Neck Squamous Cell Carcinoma Locally Recurrent Hypopharyngeal Squamous Cell Carcinoma Locally Recurrent Laryngeal Squamous Cell Carcinoma Locally Recurrent Oral Cavity Squamous Cell Carcinoma Locally Recurrent Oropharyngeal Squamous Cell Carcinoma Metastatic Head and Neck Squamous Cell Carcinoma Metastatic Hypopharyngeal Squamous Cell Carcinoma Metastatic Laryngeal Squamous Cell Carcinoma Metastatic Melanoma Metastatic Oral Cavity Squamous Cell Carcinoma Metastatic Oropharyngeal Squamous Cell Carcinoma Recurrent Melanoma Stage III Hypopharyngeal Carcinoma AJCC v8 Stage III Laryngeal Cancer AJCC v8 Stage III Lip and Oral Cavity Cancer AJCC v8 Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Stage IV Hypopharyngeal Carcinoma AJCC v8 Stage IV Laryngeal Cancer AJCC v8 Stage IV Lip and Oral Cavity Cancer AJCC v8 Stage IV Oropharyngeal (p16-Negative) Carcinoma AJCC v8 Unresectable Melanoma

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet

NCT05112601 | RECRUITING | PHASE2

81 Participants

Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-06-02

Completion: 2026-04-30

Conditions

Endometrial Adenocarcinoma Endometrial Clear Cell Adenocarcinoma Endometrial Dedifferentiated Carcinoma Endometrial Endometrioid Adenocarcinoma Endometrial Mixed Cell Adenocarcinoma Endometrial Mucinous Adenocarcinoma Endometrial Undifferentiated Carcinoma Endometrioid Adenocarcinoma Recurrent Endometrial Carcinoma

Interventions

PROCEDURE BIOLOGICAL

No Results Yet

NCT05111574 | RECRUITING | PHASE2

99 Participants

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-26

Start Date: 2022-08-11

Completion: 2025-12-19

Conditions

Anal Melanoma Bladder Melanoma Cervical Melanoma Esophageal Melanoma Gallbladder Melanoma Head and Neck Mucosal Melanoma Mucosal Melanoma Nasopharyngeal Mucosal Melanoma Oral Cavity Mucosal Melanoma Penile Mucosal Melanoma Rectal Melanoma Recurrent Mucosal Melanoma Sinonasal Mucosal Melanoma Urethral Melanoma Urinary System Mucosal Melanoma Vaginal Melanoma Vulvar Melanoma

Interventions

PROCEDURE DRUG BIOLOGICAL

No Results Yet