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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03520491 | ACTIVE_NOT_RECRUITING | PHASE2
52 Participants

A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-04-25
Completion: 2026-01-31
Conditions
Bladder Cancer
Interventions
DRUG PROCEDURE
No Results Yet
NCT03481829 | RECRUITING
1500 Participants

Early Tracking of Childhood Health Determinants (ETCHED) Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2022-04-14
Completion: 2041-12-31
Conditions
Diabetes Mellitus Obesity Fatty Liver
No Results Yet
NCT03478839 | COMPLETED
48 Participants

Study of People With Generalized Arterial Calcification of Infancy (GACI) or Autosomal Recessive Hypophosphatemic Rickets Type 2 (ARHR2)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2018-04-17
Completion: 2020-12-31
Conditions
Generalized Arterial Calcification of Infancy Autosomal Recessive Hypophosphatemic Rickets Type2
No Results Yet
NCT03410043 | ACTIVE_NOT_RECRUITING | PHASE2
173 Participants

Osimertinib, Surgery, and Radiation Therapy in Treating Patients With Stage IIIB or IV Non-small Cell Lung Cancer With EGFR Mutations, NORTHSTAR Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-01-17
Completion: 2026-04-01
Conditions
Lung Non-Small Cell Carcinoma Recurrent Lung Non-Small Cell Carcinoma Stage IIIB Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8 Stage IVA Lung Cancer AJCC v8 Stage IVB Lung Cancer AJCC v8
Interventions
DRUG RADIATION PROCEDURE
No Results Yet
NCT03388606 | RECRUITING
4100 Participants

Characterization and Treatment of Adolescent Depression

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-12-28
Completion: 2026-07-01
Conditions
Depression
Interventions
BEHAVIORAL
No Results Yet
NCT03374215 | RECRUITING
1150 Participants

Clinical and Molecular Characteristics of Primary Aldosteronism in Blacks

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-12-14
Completion: 2025-12-31
Conditions
Adrenal Gland Neoplasm Hypertension Bone Diseases, Metabolic Cardiovascular Disease Hyperinsulinemia
No Results Yet
NCT03366116 | RECRUITING | PHASE1
65 Participants

5-aza-4'-Thio-2'-Deoxycytidine (Aza-TdC) in People With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-11-05
Completion: 2026-09-30
Conditions
Neoplasms Solid Tumors
Interventions
DRUG
No Results Yet
NCT03317938 | COMPLETED | NA
236 Participants

Studies in Patients With Defecatory Disorders

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-08-14
Completion: 2024-12-31
Conditions
Fecal Incontinence Constipation
Interventions
DEVICE
No Results Yet
NCT03313128 | COMPLETED
261 Participants

SaniVac Trial - Sanitation and Oral Rotavirus Vaccine Performance

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-10-05
Completion: 2024-12-12
Conditions
Rotavirus Infections Environmental Enteric Dysfunction Enteric Infections
Interventions
OTHER
No Results Yet
NCT03303716 | RECRUITING
200 Participants

ASXL-Related Disorders Natural History Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-09-20
Completion: 2037-09-30
Conditions
Bohring-Opitz Syndrome ASXL1 Gene Mutation Shashi-Pena Syndrome ASXL2 Gene Mutation Bainbridge-Ropers Syndrome ASXL3 Gene Mutation
No Results Yet
NCT03288207 | RECRUITING | NA
325 Participants

Tailoring Mobile Health Technology to Reduce Obesity and Improve Cardiovascular Health in Resource-Limited Neighborhood Environments

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-06-21
Completion: 2026-02-09
Conditions
Obesity
Interventions
DEVICE
No Results Yet
NCT03266055 | ACTIVE_NOT_RECRUITING | NA
59 Participants

Effects of Blueberry on Gut Microbiota and Metabolic Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-09-01
Completion: 2019-01-14
Conditions
Gut Microbiota Metabolic Syndrome
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT03259685 | ACTIVE_NOT_RECRUITING | NA
41 Participants

Effect of Non-nutritive Sweeteners of High Sugar Sweetened Beverages on Metabolic Health and Gut Microbiome

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-10-18
Completion: 2021-12-20
Conditions
Gut Microbiota Metabolic Syndrome
Interventions
OTHER
No Results Yet
NCT03245242 | ACTIVE_NOT_RECRUITING
85 Participants

Pediatric Urology Recovery After Surgery Endeavor (PURSUE)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-04-01
Completion: 2026-10-31
Conditions
Urologic Surgical Procedures Urinary Bladder, Neurogenic Urinary Bladder Diseases
Interventions
OTHER
No Results Yet
NCT03226704 | ENROLLING_BY_INVITATION
120 Participants

Leukapheresis for CAR or Adoptive Cell Therapy Manufacturing

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-08-14
Completion: 2030-01-31
Conditions
Leukemia Lymphoma Acute Lymphoblastic Leukemia Diffuse Large B Cell Lymphoma Non-Hodgkin's Lymphoma
Interventions
PROCEDURE
No Results Yet
NCT03225144 | RECRUITING
360 Participants

Investigating Complex Neurodegenerative Disorders Related to Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-10-11
Completion: 2027-10-30
Conditions
Frontotemporal Dementia Amyotrophic Lateral Sclerosis Progressive Supranuclear Palsy
No Results Yet
NCT03223610 | RECRUITING | PHASE1/PHASE2
145 Participants

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-02-09
Completion: 2026-12-01
Conditions
Lymphoma Non-Hodgkin Lymphoma Diffuse Large B-Cell Lymphoma Burkitt Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT03206099 | RECRUITING
20000 Participants

NIAID Centralized Sequencing Protocol

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-07-31
Completion: 2029-12-31
Conditions
Atopy Primary Immunodeficiency Autoimmunity Autoinflammation
No Results Yet
NCT03167437 | RECRUITING | PHASE1/PHASE2
35 Participants

An Open-Label, Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-10-30
Completion: 2026-06-30
Conditions
Crohn's Disease
Interventions
DRUG
No Results Yet
NCT03128905 | COMPLETED | PHASE3
111 Participants

Trial of Colchicine Versus Prednisone for the Treatment of Acute CPPD Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-02-05
Completion: 2022-05-13
Conditions
Chondrocalcinosis
Interventions
DRUG
No Results Yet
NCT03106454 | COMPLETED | PHASE3
58 Participants

Ovulation Incidence in Oral Contraceptive Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2014-08-31
Completion: 2024-01-31
Conditions
Contraception Ovulation
Interventions
DRUG
No Results Yet
NCT03104569 | NOT_YET_RECRUITING | NA
100 Participants

Effect of 37℃ Non-ionic Contrast Agent During ERCP Procedure in Hilar Cholangiocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-04-01
Completion: 2028-12-01
Conditions
Cholangitis
Interventions
PROCEDURE
No Results Yet
NCT03055286 | TERMINATED | PHASE1/PHASE2
15 Participants

Clinical Study of CWP232291 in Acute Myeloid Leukemia Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-02-06
Completion: 2025-08-26
Conditions
Acute Myeloid Leukemia
Interventions
DRUG
No Results Yet
NCT03049462 | RECRUITING | PHASE1
100 Participants

The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-03-13
Completion: 2026-09-30
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT03000244 | RECRUITING
2000 Participants

Long-Term Follow-up of People Undergoing Hematopoietic Stem Cell Transplantation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-04-26
Completion: 2050-08-12
Conditions
Hematopoietic Stem Cell Transplantation Tissue Donors
No Results Yet
NCT02979873 | ACTIVE_NOT_RECRUITING | PHASE2
84 Participants

Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2016-12-19
Completion: 2026-09-03
Conditions
Severe Aplastic Anemia
Interventions
DRUG
No Results Yet
NCT02974582 | RECRUITING | NA
530 Participants

Understanding How Cigarette Direct Mail Marketing Influences Smoking Behaviors Among High and Low Socioeconomic Status Young Adult Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2026-10-17
Completion: 2027-10-06
Conditions
Nicotine Dependence
Interventions
BEHAVIORAL
No Results Yet
NCT02941263 | COMPLETED
20 Participants

Natural History of Geographic Atrophy Associated With Age-Related Macular Degeneration

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2017-03-08
Completion: 2024-05-22
Conditions
Age-Related Macular Degeneration
No Results Yet
NCT02911103 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
5 Participants

Deep Brain Stimulation Surgery for Focal Hand Dystonia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-01-17
Completion: 2029-02-02
Conditions
Dystonia Focal Dystonia Musician's Dystonia
Interventions
PROCEDURE DEVICE
No Results Yet
NCT02905591 | ACTIVE_NOT_RECRUITING | PHASE2
43 Participants

A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2018-11-16
Completion: 2025-07-17
Conditions
Carcinoma, Non-Small-Cell Lung Non-Small Cell Lung Cancer Nonsmall Cell Lung Cancer Non-Small-Cell Lung Carcinoma NSCLC
Interventions
DRUG
No Results Yet
NCT02900053 | COMPLETED | NA
63 Participants

Post-traumatic Stress Disorder Treatment Using Transcranial Direct Current Stimulation (tDCS) Enhancement of Trauma-focused Therapy : a Two-arm Randomized Controlled Multicentric Study.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-01-31
Completion: 2021-10-01
Conditions
Post-traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
NCT02821767 | RECRUITING
1000 Participants

Natural History, Pathogenesis, and Outcome of Ocular Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2016-08-03
Completion: 2026-07-01
Conditions
Eye Disease
No Results Yet
NCT02773043 | COMPLETED | NA
36 Participants

Evaluation of Myocardial Perfusion Reserve

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2015-12-31
Completion: 2019-07-31
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT02759744 | ENROLLING_BY_INVITATION | NA
30 Participants

Fusion Guided Focal Laser Ablation of Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2017-10-13
Completion: 2027-01-21
Conditions
Prostate Cancer Prostate Neoplasms
Interventions
DEVICE
No Results Yet
NCT02709226 | COMPLETED | PHASE1
17 Participants

Dose Escalation Trial of Re-irradiation in Good Prognosis Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2016-06-15
Completion: 2022-12-16
Conditions
Astrocytoma, Grade IV Giant Cell Glioblastoma Glioblastoma Multiforme Gliosarcoma
Interventions
RADIATION
No Results Yet
NCT02669225 | COMPLETED | EARLY_PHASE1
22 Participants

Brain Amyloid- Retention During Wakefulness and Following Emergence From Sleep in Healthy People

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2016-05-02
Completion: 2017-01-24
Conditions
Normal Physiology
Interventions
OTHER
No Results Yet
NCT02617966 | RECRUITING
500 Participants

Rod and Cone Mediated Function in Retinal Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2016-03-24
Completion: 2029-12-30
Conditions
Retinal Degeneration Retinitis Pigmentosa Stargardt's Disease
No Results Yet
NCT02595957 | RECRUITING
5000 Participants

Genomic Services Research Program

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2014-09-16
Completion: 2028-12-31
Conditions
Colon Cancer Breast Cancer
No Results Yet
NCT02583646 | RECRUITING
150 Participants

Investigating the Impact of Obesity on Pubertal Development in Girls

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2015-12-15
Completion: 2026-09-30
Conditions
Obesity Puberty Normal Physiology
No Results Yet
NCT02579967 | RECRUITING | PHASE2
354 Participants

Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2015-11-19
Completion: 2031-12-31
Conditions
Primary T-cell Immunodeficiency Disorders Common Variable Immunodeficiency Immune System Diseases Autoimmune Lymphoproliferative Lymphoproliferative Disorders
Interventions
DRUG PROCEDURE
No Results Yet
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