Clinical Trials
Showing trials with last updates posted in 2025.
1200
Participants
Adult and Juvenile Myositis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1995-06-07
Conditions
Dermatomyositis
Polymyositis
Inclusion Body Myositis
No Results Yet
307
Participants
Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2001-11-01
Conditions
Sickle Cell Disease
Sickle Cell Trait
No Results Yet
986
Participants
Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2008-02-19
Conditions
Pulmonary Hypertension
Sickle Cell Anemia
Sickle Cell Disease
No Results Yet
4000
Participants
Natural History of Stroke: Cause and Development
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2001-01-26
Conditions
Brain Disease
Ischemic Attack, Transient
Cerebrovascular Accident
Cerebrovascular Disorder
Vascular Diseases
No Results Yet
622
Participants
Treatment of Hemochromatosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-26
Start Date:
2001-01-01
Completion:
2025-12-31
Conditions
Hemochromatosis
Interventions
PROCEDURE
No Results Yet
1029
Participants
Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2000-12-06
Conditions
HIV
Kaposi's Sarcoma
Lymphomas
Multicentric Castleman's Disease
Primary Effusion Lymphoma
No Results Yet
690
Participants
Study of Adrenal Gland Tumors
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2002-07-01
Conditions
Adrenal Gland Neoplasm
No Results Yet
60
Participants
Study of Chediak-Higashi Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2002-09-10
Conditions
Chediak-Higashi Syndrome
No Results Yet
250
Participants
Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2001-02-15
Conditions
Hemangioblastoma
Hippel Lindau Disease
No Results Yet
805
Participants
Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1991-03-15
Conditions
Hepatitis C
Hepatitis B
No Results Yet
2000
Participants
Diabetes and Heart Disease Risk in Blacks
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-10-21
Conditions
Cardiovascular Diseases
Diabetes
Obesity
Hypertension
No Results Yet
5000
Participants
Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
2001-01-11
Conditions
Blood Donors
Research Subjects
Apheresis
No Results Yet
709
Participants
Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1999-05-10
Conditions
Cockayne Syndrome
Skin Neoplasms
Xeroderma Pigmentosum
Trichothiodystrophy Syndromes
Genodermatosis
No Results Yet
750
Participants
Evaluation of Patients With HAM/TSP
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-04-06
Conditions
HTLV-I Infection
Tropical Spastic Paraparesis
No Results Yet
500
Participants
Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-12-13
Conditions
McCune-Albright Syndrome
No Results Yet
130
Participants
Study of Smith-Lemli-Opitz Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-09-13
Conditions
Smith-Lemli-Opitz Syndrome
Interventions
DRUG
No Results Yet
800
Participants
Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-10-10
Conditions
Malaria
Intestinal Worms
GI Protozoa
Echiniococcus
Strongyloides
No Results Yet
10000
Participants
Screening for Hematology Branch Protocols
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1996-12-31
Conditions
Hematologic Disease and Disorders
Donors
Healthy Volunteer
No Results Yet
3500
Participants
Role of Genetic Factors in the Development of Lung Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1996-09-13
Conditions
Cystic Fibrosis
Pulmonary Fibrosis
Tuberous Sclerosis
Asthma
Pulmonary Sarcoidosis
No Results Yet
635
Participants
Tissue Biopsy and Imaging Studies in HIV-Infected Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1994-11-30
Conditions
HIV
ICL
Healthy Volunteers
No Results Yet
5000
Participants
Genetic Analysis of Immune Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1995-06-06
Conditions
DOK 8
STAT1
GATA2
Immunodeficiency
STAT3
No Results Yet
2000
Participants
Study of the Disease Process of Lymphangioleiomyomatosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1995-12-18
Conditions
Lung Disease
Pneumothorax
Tuberous Sclerosis
Lymphangioleiomyomatosis
Interventions
DEVICE
No Results Yet
1387
Participants
Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1995-12-14
Conditions
Cushing's Syndrome
Pituitary Adenoma
Carney Complex
Primary Pigmented Nodular Adrenocortical Disease
Peutz-Jeghers Syndrome
Interventions
DRUG
No Results Yet
1500
Participants
Study of Proteus Syndrome and Related Congenital Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1994-04-27
Conditions
Proteus Syndrome
PIK3CA Related Overgrowth Spectrum
No Results Yet
537
Participants
Pathogenesis of Glomerulosclerosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1996-04-16
Conditions
Glomerular Disease
No Results Yet
5000
Participants
Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1994-03-10
Conditions
Familial Mediterranean Fever (FMF)
Autoinflammation
Periodic Fever
Fever
Genetic Diseases
ROSAH
ALPK1
No Results Yet
4100
Participants
Studies of Blood Flow to the Brain During Thought
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1993-09-17
Conditions
Healthy Volunteer
No Results Yet
3600
Participants
Detection and Characterization of Host Defense Defects
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1993-09-01
Conditions
Immune Defects
No Results Yet
800
Participants
Fungal Infection Susceptibility
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1993-04-01
Conditions
Pulmonary Cryptococcosis
Cryptococcal Meningitis
Cryptococcosis
Cryptococcal Infection
Cryptococcal Pneumonia
No Results Yet
273
Participants
Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1991-10-29
Conditions
Zollinger Ellison Syndrome
No Results Yet
1158
Participants
Perimenopause-Related Mood and Behavioral Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1989-03-06
Conditions
Mood Disorder
No Results Yet
1000
Participants
Genetic Studies of Lysosomal Storage Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1995-03-08
Conditions
Lysosomal Storage Disorders
Gaucher Disease
Parkinson Disease
No Results Yet
2000
Participants
Botulinum Toxin for the Treatment of Involuntary Movement Disorders
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1989-10-26
Conditions
Movement Disorders
No Results Yet
1000
Participants
Immune Regulation in Ulcerative Colitis or Crohn s Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1998-08-07
Conditions
Inflammatory Bowel Disease
Ulcerative Colitis
Chrohn's Disease
No Results Yet
5201
Participants
Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-26
Start Date:
1985-04-02
Conditions
Hereditary Neoplasms
Cancer
Genetic Predisposition to Cancer
Environment
No Results Yet
180
Participants
Validation of Hindi Version Oral Health Impact Profile for Periodontitis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-11-12
Completion:
2025-12-31
Conditions
Periodontitis
Interventions
OTHER
No Results Yet
118
Participants
Comparison of Obturation Quality and Lateral Canal Fill (by Sealer): Ultrasonic-Activated Versus Non-Ultrasonic Conventional Irrigation Techniques in Root Canal Treatment - A Randomized Controlled Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-01
Completion:
2026-05-30
Conditions
Comparison Between Two Type of Irrigation Systems
Interventions
OTHER
No Results Yet
60
Participants
To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-14
Completion:
2026-11-30
Conditions
KRAS G12D Mutations
Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions
DRUG
No Results Yet
20
Participants
Evaluation of the Restera™ Serene™ System in Adults With Obstructive Sleep Apnea
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-31
Completion:
2026-09-30
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
No Results Yet
120
Participants
Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation Compared to Single Device Treatments in Patients With Diabetes Mellitus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-08-06
Completion:
2026-12-16
Conditions
Diabetes Mellitus
Coronary Arterial Disease (CAD)
de Novo Coronary Lesions
De Novo Stenosis
Interventions
PROCEDURE
No Results Yet
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