Clinical Trials

Showing trials with last updates posted in 2025.

NCT00017914 | RECRUITING
1200 Participants

Adult and Juvenile Myositis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1995-06-07
Conditions
Dermatomyositis Polymyositis Inclusion Body Myositis
No Results Yet
NCT00012545 | COMPLETED
307 Participants

Collection and Storage of Umbilical Cord Stem Cells for Treatment of Sickle Cell Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2001-11-01
Conditions
Sickle Cell Disease Sickle Cell Trait
No Results Yet
NCT00011648 | COMPLETED
986 Participants

Secondary Pulmonary Hypertension in Adults With Sickle Cell Anemia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2008-02-19
Conditions
Pulmonary Hypertension Sickle Cell Anemia Sickle Cell Disease
No Results Yet
NCT00009243 | RECRUITING
4000 Participants

Natural History of Stroke: Cause and Development

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2001-01-26
Conditions
Brain Disease Ischemic Attack, Transient Cerebrovascular Accident Cerebrovascular Disorder Vascular Diseases
No Results Yet
NCT00007150 | ACTIVE_NOT_RECRUITING | PHASE2
622 Participants

Treatment of Hemochromatosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-26
Start Date: 2001-01-01
Completion: 2025-12-31
Conditions
Hemochromatosis
Interventions
PROCEDURE
No Results Yet
NCT00006518 | RECRUITING
1029 Participants

Specimen Collections From Participants With HIV Infection, KSHV Infection, Viral-Related Pre-malignant Lesions and Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2000-12-06
Conditions
HIV Kaposi's Sarcoma Lymphomas Multicentric Castleman's Disease Primary Effusion Lymphoma
No Results Yet
NCT00005927 | COMPLETED
690 Participants

Study of Adrenal Gland Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2002-07-01
Conditions
Adrenal Gland Neoplasm
No Results Yet
NCT00005917 | RECRUITING
60 Participants

Study of Chediak-Higashi Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2002-09-10
Conditions
Chediak-Higashi Syndrome
No Results Yet
NCT00005902 | ACTIVE_NOT_RECRUITING
250 Participants

Study of Brain and Spinal Cord Tumor Growth and Cyst Development in Patients With Von Hippel Lindau Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2001-02-15
Conditions
Hemangioblastoma Hippel Lindau Disease
No Results Yet
NCT00004850 | COMPLETED
805 Participants

Epidemiology, Infectivity and Natural History of Hepatitis C Virus Infection

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1991-03-15
Conditions
Hepatitis C Hepatitis B
No Results Yet
NCT00001853 | RECRUITING
2000 Participants

Diabetes and Heart Disease Risk in Blacks

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-10-21
Conditions
Cardiovascular Diseases Diabetes Obesity Hypertension
No Results Yet
NCT00001846 | RECRUITING
5000 Participants

Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 2001-01-11
Conditions
Blood Donors Research Subjects Apheresis
No Results Yet
NCT00001813 | COMPLETED
709 Participants

Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum, Cockayne Syndrome, or Trichothiodystrophy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1999-05-10
Conditions
Cockayne Syndrome Skin Neoplasms Xeroderma Pigmentosum Trichothiodystrophy Syndromes Genodermatosis
No Results Yet
NCT00001778 | RECRUITING
750 Participants

Evaluation of Patients With HAM/TSP

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-04-06
Conditions
HTLV-I Infection Tropical Spastic Paraparesis
No Results Yet
NCT00001727 | RECRUITING
500 Participants

Screening and Natural History of Patients With Polyostotic Fibrous Dysplasia and the McCune-Albright Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-12-13
Conditions
McCune-Albright Syndrome
No Results Yet
NCT00001721 | COMPLETED
130 Participants

Study of Smith-Lemli-Opitz Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-09-13
Conditions
Smith-Lemli-Opitz Syndrome
Interventions
DRUG
No Results Yet
NCT00001645 | RECRUITING
800 Participants

Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-10-10
Conditions
Malaria Intestinal Worms GI Protozoa Echiniococcus Strongyloides
No Results Yet
NCT00001620 | ENROLLING_BY_INVITATION
10000 Participants

Screening for Hematology Branch Protocols

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1996-12-31
Conditions
Hematologic Disease and Disorders Donors Healthy Volunteer
No Results Yet
NCT00001532 | RECRUITING
3500 Participants

Role of Genetic Factors in the Development of Lung Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1996-09-13
Conditions
Cystic Fibrosis Pulmonary Fibrosis Tuberous Sclerosis Asthma Pulmonary Sarcoidosis
No Results Yet
NCT00001471 | RECRUITING
635 Participants

Tissue Biopsy and Imaging Studies in HIV-Infected Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1994-11-30
Conditions
HIV ICL Healthy Volunteers
No Results Yet
NCT00001467 | RECRUITING
5000 Participants

Genetic Analysis of Immune Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1995-06-06
Conditions
DOK 8 STAT1 GATA2 Immunodeficiency STAT3
No Results Yet
NCT00001465 | RECRUITING
2000 Participants

Study of the Disease Process of Lymphangioleiomyomatosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1995-12-18
Conditions
Lung Disease Pneumothorax Tuberous Sclerosis Lymphangioleiomyomatosis
Interventions
DEVICE
No Results Yet
NCT00001452 | COMPLETED
1387 Participants

Defining the Genetic Basis for the Development of Primary Pigmented Nodular Adrenocortical Disease (PPNAD) and the Carney Complex

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1995-12-14
Conditions
Cushing's Syndrome Pituitary Adenoma Carney Complex Primary Pigmented Nodular Adrenocortical Disease Peutz-Jeghers Syndrome
Interventions
DRUG
No Results Yet
NCT00001403 | RECRUITING
1500 Participants

Study of Proteus Syndrome and Related Congenital Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1994-04-27
Conditions
Proteus Syndrome PIK3CA Related Overgrowth Spectrum
No Results Yet
NCT00001392 | COMPLETED
537 Participants

Pathogenesis of Glomerulosclerosis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1996-04-16
Conditions
Glomerular Disease
No Results Yet
NCT00001373 | RECRUITING
5000 Participants

Familial Mediterranean Fever and Related Disorders: Genetics and Disease Characteristics

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1994-03-10
Conditions
Familial Mediterranean Fever (FMF) Autoinflammation Periodic Fever Fever Genetic Diseases ROSAH ALPK1
No Results Yet
NCT00001360 | RECRUITING
4100 Participants

Studies of Blood Flow to the Brain During Thought

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1993-09-17
Conditions
Healthy Volunteer
No Results Yet
NCT00001355 | RECRUITING
3600 Participants

Detection and Characterization of Host Defense Defects

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1993-09-01
Conditions
Immune Defects
No Results Yet
NCT00001352 | RECRUITING
800 Participants

Fungal Infection Susceptibility

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1993-04-01
Conditions
Pulmonary Cryptococcosis Cryptococcal Meningitis Cryptococcosis Cryptococcal Infection Cryptococcal Pneumonia
No Results Yet
NCT00001254 | COMPLETED
273 Participants

Evaluating Pancreatic Tumors in Patients With Zollinger-Ellison Syndrome

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1991-10-29
Conditions
Zollinger Ellison Syndrome
No Results Yet
NCT00001231 | COMPLETED
1158 Participants

Perimenopause-Related Mood and Behavioral Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1989-03-06
Conditions
Mood Disorder
No Results Yet
NCT00001215 | ENROLLING_BY_INVITATION
1000 Participants

Genetic Studies of Lysosomal Storage Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1995-03-08
Conditions
Lysosomal Storage Disorders Gaucher Disease Parkinson Disease
No Results Yet
NCT00001208 | RECRUITING
2000 Participants

Botulinum Toxin for the Treatment of Involuntary Movement Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1989-10-26
Conditions
Movement Disorders
No Results Yet
NCT00001184 | RECRUITING
1000 Participants

Immune Regulation in Ulcerative Colitis or Crohn s Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1998-08-07
Conditions
Inflammatory Bowel Disease Ulcerative Colitis Chrohn's Disease
No Results Yet
NCT00001163 | ACTIVE_NOT_RECRUITING
5201 Participants

Clinical, Laboratory, and Epidemiologic Characterization of Individuals and Families at High Risk of Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-26
Start Date: 1985-04-02
Conditions
Hereditary Neoplasms Cancer Genetic Predisposition to Cancer Environment
No Results Yet
NCT07303491 | RECRUITING
180 Participants

Validation of Hindi Version Oral Health Impact Profile for Periodontitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-12
Completion: 2025-12-31
Conditions
Periodontitis
Interventions
OTHER
No Results Yet
NCT07303478 | NOT_YET_RECRUITING | NA
118 Participants

Comparison of Obturation Quality and Lateral Canal Fill (by Sealer): Ultrasonic-Activated Versus Non-Ultrasonic Conventional Irrigation Techniques in Root Canal Treatment - A Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-01
Completion: 2026-05-30
Conditions
Comparison Between Two Type of Irrigation Systems
Interventions
OTHER
No Results Yet
NCT07303465 | RECRUITING | PHASE2
60 Participants

To Evaluate the Safety and Efficacy of RNK08954 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-14
Completion: 2026-11-30
Conditions
KRAS G12D Mutations Pancreatic Ductal Adenocarcinoma (PDAC)
Interventions
DRUG
No Results Yet
NCT07303452 | RECRUITING | NA
20 Participants

Evaluation of the Restera™ Serene™ System in Adults With Obstructive Sleep Apnea

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-31
Completion: 2026-09-30
Conditions
Obstructive Sleep Apnea
Interventions
DEVICE
No Results Yet
NCT07303439 | RECRUITING | NA
120 Participants

Randomised Trial of Dual Device Treatment Involving Drug-coated Balloon Angioplasty and Drug-eluting Stent Implantation Compared to Single Device Treatments in Patients With Diabetes Mellitus

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-08-06
Completion: 2026-12-16
Conditions
Diabetes Mellitus Coronary Arterial Disease (CAD) de Novo Coronary Lesions De Novo Stenosis
Interventions
PROCEDURE
No Results Yet
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