Clinical Trials Updated in 2025

NCT07232732 | RECRUITING | PHASE1

60 Participants

A Study of LY3549492 in Healthy Participants and Participants With Overweight or Obesity

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-27

Completion: 2026-02-28

Conditions

Healthy Obesity Overweight

Interventions

DRUG

No Results Yet

NCT07232017 | NOT_YET_RECRUITING

1520 Participants

Implementation of Intensive Hypertension Management Approaches: Cleveland Clinic

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-31

Completion: 2029-04-30

Conditions

Hypertension (HTN)

Interventions

OTHER

No Results Yet

NCT07230977 | RECRUITING | PHASE1

280 Participants

GenSci139 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-19

Completion: 2028-07-07

Conditions

Advanced Solid Tumors

Interventions

DRUG

No Results Yet

NCT07230691 | RECRUITING

380 Participants

A Study of Clinical Outcomes in Participants With EGFR Mutated Advanced Non-Small Cell Lung Cancer (NSCLC) in a Real-World Setting

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-03

Completion: 2030-11-19

Conditions

Carcinoma, Non-Small-Cell Lung

No Results Yet

NCT07229638 | NOT_YET_RECRUITING | PHASE1/PHASE2

60 Participants

A IB/II Phase Clinical Study on the Safety, Tolerability, and Efficacy of SHR-9839(sc) in Combination Anti-tumor Therapy in Patients With Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-31

Completion: 2028-06-30

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT07228377 | RECRUITING | NA

25 Participants

Digital Intervention for Symptom Management in Cancer and Opioid Sparing Using Virtual Reality (DISCOVR) Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-01

Completion: 2026-08-31

Conditions

Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07228156 | ENROLLING_BY_INVITATION | NA

60 Participants

Study to Evaluate Xtresse Serum in Individuals With Thinning Hair

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-17

Completion: 2026-08-31

Conditions

Thin Hair Hair Loss Alopecia Thinning Hair

Interventions

OTHER

No Results Yet

NCT07226843 | NOT_YET_RECRUITING | PHASE1

360 Participants

A Study of LY4584180 in Adult Participants With Previously Treated Blood Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-02-28

Completion: 2027-02-28

Conditions

Lymphoma, Non-Hodgkin's Lymphoma, Diffuse Large B-Cell Follicular Lymphoma

Interventions

DRUG

No Results Yet

NCT07225738 | NOT_YET_RECRUITING

700 Participants

A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-24

Completion: 2027-05-13

Conditions

Multiple Myeloma

Interventions

OTHER

No Results Yet

NCT07225504 | RECRUITING | PHASE3

1275 Participants

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-11

Completion: 2030-12-03

Conditions

Secondary Progressive Multiple Sclerosis (SPMS)

Interventions

DRUG

No Results Yet

NCT07225361 | RECRUITING | PHASE4

40 Participants

Ublituximab (Briumvi) for Early Forms of Relapsing Multiple Sclerosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-28

Completion: 2029-03-15

Conditions

Multiple Sclerosis Multiple Sclerosis (MS) - Relapsing-remitting

Interventions

DRUG

No Results Yet

NCT07224477 | NOT_YET_RECRUITING | PHASE2

525 Participants

A Clinical Study of V540A in Healthy Female Participants (V540A-005)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-07-20

Completion: 2028-04-04

Conditions

Healthy

Interventions

BIOLOGICAL

No Results Yet

NCT07223593 | RECRUITING | PHASE3

1205 Participants

Efficacy and Safety of Orforglipron in Participants With Peripheral Artery Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-31

Completion: 2028-06-30

Conditions

Peripheral Arterial Disease

Interventions

DRUG

No Results Yet

NCT07223125 | RECRUITING | PHASE1

360 Participants

A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-10

Completion: 2026-12-15

Conditions

Advanced-stage Solid Tumors

Interventions

DRUG

No Results Yet

NCT07222605 | WITHHELD

[Trial of device that is not approved or cleared by the U.S. FDA]

Last Updated: 2025-12-24

No Results Yet

NCT07222475 | RECRUITING | NA

30 Participants

Writing Relaxing Beats in Adolescents Who Have Sickle Cell Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-05

Completion: 2026-07-31

Conditions

Sickle Cell Disease

Interventions

BEHAVIORAL

No Results Yet

NCT07222462 | RECRUITING | NA

300 Participants

A Superiority Trial of Radiofrequency Ablation for Low Back Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2029-03-31

Conditions

Chronic Low Back Pain (CLBP)

Interventions

PROCEDURE

No Results Yet

NCT07222358 | NOT_YET_RECRUITING

100 Participants

Multi-component Remote Assessment in Adult Survivors Using a Connected Technology Platform for Healthcare Delivery

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2026-08-31

Conditions

Childhood Cancer

Interventions

BEHAVIORAL

No Results Yet

NCT07222137 | NOT_YET_RECRUITING | PHASE3

150 Participants

A Study of Baricitinib (LY3009104) for the Delay of Stage 3 Type 1 Diabetes in At-Risk Children and Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2031-07-31

Conditions

Diabetes Mellitus, Type 1

Interventions

DRUG

No Results Yet

NCT07221591 | RECRUITING | PHASE1

100 Participants

A Study in Healthy People to Compare How 2 Different Formulations of Survodutide Are Taken up by the Body

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-05

Completion: 2026-08-24

Conditions

Healthy

Interventions

DRUG

No Results Yet

NCT07220824 | RECRUITING

200 Participants

A Study of Guselkumab in Participants With Psoriatic Arthritis (PsA) in a Real-World Setting

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-04

Completion: 2027-07-31

Conditions

Arthritis, Psoriatic

No Results Yet

NCT07220577 | RECRUITING | PHASE2

84 Participants

Phase 2a Study to Assess the Efficacy,Safety and Tolerability of GIA632 in Adult Participants With Moderate to Severe Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-10

Completion: 2027-05-24

Conditions

Atopic Dermatitis

Interventions

DRUG OTHER

No Results Yet

NCT07219966 | RECRUITING | PHASE3

1100 Participants

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-15

Completion: 2028-04-30

Conditions

Alcohol Use Disorder

Interventions

DRUG

No Results Yet

NCT07219550 | RECRUITING | PHASE1

58 Participants

A Study of MK-1084 in Participants With Hepatic Impairment and Healthy Volunteers (MK-1084-017)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-05

Completion: 2026-06-30

Conditions

Healthy Hepatic Impairment

Interventions

DRUG

No Results Yet

NCT07219212 | RECRUITING | PHASE1

30 Participants

A Study of JNJ-90301900 in Combination With Chemoradiation Therapy in Participants With Locally Advanced Head and Neck Squamous Cell Carcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-11

Completion: 2028-07-14

Conditions

Squamous Cell Carcinoma of Head and Neck

Interventions

DRUG RADIATION

No Results Yet

NCT07218393 | NOT_YET_RECRUITING

100 Participants

A Study About the Diagnosis and Management of Hereditary Angioedema (HAE) in Egypt

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2026-03-15

Completion: 2026-12-01

Conditions

Hereditary Angioedema (HAE)

Interventions

OTHER

No Results Yet

NCT07218367 | NOT_YET_RECRUITING | PHASE1

12 Participants

Phase I Trial of pH Resections of GBM at VA

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-02-01

Completion: 2031-02-01

Conditions

Glioblastoma

Interventions

PROCEDURE

No Results Yet

NCT07216482 | RECRUITING | PHASE3

975 Participants

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-11-11

Completion: 2026-12-02

Conditions

Hyperlipidemia

Interventions

DRUG

No Results Yet

NCT07216118 | NOT_YET_RECRUITING | NA

104 Participants

Pilot-Testing Strategies to Improve Outcomes for Youth With Type 2 Diabetes by Addressing Health-Related Social Needs

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-04-30

Completion: 2028-04-30

Conditions

Diabetes in Adolescence Type 2 Diabetes Social Needs

Interventions

BEHAVIORAL

No Results Yet

NCT07215559 | RECRUITING | PHASE2

200 Participants

A Study of Macupatide (LY3532226) and Eloralintide (LY3841136), Alone or in Combination, in Adults With Obesity or Overweight and With Type 2 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-16

Completion: 2027-03-31

Conditions

Obesity Overweight Diabetes Mellitus, Type 2

Interventions

DRUG

No Results Yet

NCT07214727 | RECRUITING | PHASE1

50 Participants

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-15

Completion: 2030-03-31

Conditions

Alzheimer's Disease

Interventions

DRUG

No Results Yet

NCT07214233 | RECRUITING | NA

60 Participants

Youth Empowerment and Safety Intervention

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2027-11-30

Conditions

Suicide Self-Injurious Behavior

Interventions

BEHAVIORAL

No Results Yet

NCT07209657 | NOT_YET_RECRUITING | NA

10 Participants

Describing the Effect of Familiar Song on Arousal and Awareness for Children With Disorders of Consciousness (DoC)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2028-11-30

Conditions

Disorder of Consciousness Acquired Brain Injury

Interventions

BEHAVIORAL

No Results Yet

NCT07209111 | RECRUITING | PHASE2

150 Participants

A Clinical Study of MK-1084 in People With Advanced Solid Tumors (MK-1084-014)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-12-04

Completion: 2032-04-09

Conditions

Neoplasm Malignant

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT07208409 | NOT_YET_RECRUITING | NA

60 Participants

Pleurodesis in Small-bore Chest Tube

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-02-01

Completion: 2027-01-31

Conditions

Pleural Effusion, Malignant

Interventions

DEVICE

No Results Yet

NCT07206472 | NOT_YET_RECRUITING

2560 Participants

A Study of Bempedoic Acid or Its Single-pill Combination Therapy With Ezetimibe in Patients With Primary Hypercholesterolaemia or Mixed Dyslipidaemia

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-30

Completion: 2028-09-01

Conditions

Primary Hypercholesterolaemia Mixed Dyslipidemia

Interventions

DRUG

No Results Yet

NCT07202884 | RECRUITING | PHASE3

1000 Participants

A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-09-30

Completion: 2028-03-31

Conditions

Urinary Incontinence,Stress

Interventions

DRUG

No Results Yet

NCT07198945 | NOT_YET_RECRUITING | NA

546 Participants

Six Versus Twelve Month Index Follow-up After Large Colon Polyp Resection

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2026-01-31

Completion: 2029-07-31

Conditions

Colon Cancer Colon Polyp Adenoma Serrated Polyp Recurrence, Local Neoplasm Endoscopic Resection

Interventions

PROCEDURE

No Results Yet

NCT07198334 | COMPLETED | NA

26 Participants

The Effect of Daily Brief Heat Exposures on Heat Acclimation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2020-10-01

Completion: 2024-05-31

Conditions

Healthy Participants

Interventions

OTHER

No Results Yet

NCT07198100 | RECRUITING | NA

120 Participants

tVNS, Motivation, and Insulin Sensitivity

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2025-10-10

Completion: 2027-12-31

Conditions

Major Depressive Disorder (MDD)

Interventions

DEVICE DIAGNOSTIC_TEST

No Results Yet