Clinical Trials

Showing trials with last updates posted in 2025.

NCT07079475 | RECRUITING | PHASE1/PHASE2
200 Participants

Study of Oral EGFR Inhibitor DZD6008 Combined With Sunvozertinib in Patients Who Have Advanced NSCLC With EGFR Mutations (TIAN-SHAN8)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-31
Completion: 2028-12-31
Conditions
Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT07079462 | RECRUITING | PHASE2
40 Participants

Comparing 68Ga-FAPI PET-Guided Abdominal Radiotherapy Combined With Second-Line Standard Therapy and Cadonilimab Versus Second-Line Standard Therapy in Colorectal Cancer With Peritoneal Metastasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-03-01
Completion: 2026-03-01
Conditions
Colorectal Cancer Peritoneal (Metastatic) Cancer FAPI PET
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT07075861 | RECRUITING
75 Participants

The ARTEMIS Data Collection Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-08-10
Completion: 2028-08-10
Conditions
Aortic Regurgitation Disease
No Results Yet
NCT07074756 | RECRUITING | NA
120 Participants

A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-12
Completion: 2028-08-31
Conditions
Glioma Recurrent Glioma
Interventions
DRUG PROCEDURE OTHER BEHAVIORAL
No Results Yet
NCT07069725 | RECRUITING | PHASE1
12 Participants

The Phase 1, Open-label, PET Trial Designed to Investigate the Effect of AZD2389 on FAP Occupancy in the Liver in Participants With Advanced Liver Fibrosis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-26
Completion: 2026-03-31
Conditions
Liver Fibrosis Hepatic Cirrhosis
Interventions
DRUG DIAGNOSTIC_TEST
No Results Yet
NCT07063589 | RECRUITING
350 Participants

Cannabis Use Patterns Among Young Adults and Associations With Social and Health Outcomes.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-16
Completion: 2027-08-31
Conditions
Cannabis Use
Interventions
OTHER
No Results Yet
NCT07061925 | COMPLETED | PHASE2
169 Participants

To Evaluate the Efficacy and Safety of ALC-2203 in Patients With Acute Bronchitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-23
Completion: 2025-11-21
Conditions
Acute Bronchitis
Interventions
DRUG
No Results Yet
NCT07046546 | RECRUITING | NA
10 Participants

Thyroid Artery Goitre Embolization Trial A Pilot Study Investigating Thyroid Artery Embolisation as a Treatment for Large Thyroid Nodules

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-29
Completion: 2026-11-30
Conditions
Thyroid Nodule (Benign) Graves Disease Goitre
Interventions
PROCEDURE
No Results Yet
NCT07040722 | RECRUITING | NA
12 Participants

Effects of the Use of an Immersive Virtual Reality Device on Handwriting in Children Aged 6 to 13 With Handwriting Difficulties ( RVALIGO )

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-01
Completion: 2027-09-01
Conditions
Children With a Need of Rehabilitation for Handwriting
Interventions
OTHER
No Results Yet
NCT07038902 | ACTIVE_NOT_RECRUITING | NA
24 Participants

A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-01
Completion: 2026-12-01
Conditions
Malocclusion, Class I/II Crowding Maxillary First Molar Distalization
Interventions
DEVICE
No Results Yet
NCT07036081 | RECRUITING | NA
40 Participants

A Single Arm Intervention Study to Assess the Acceptability, Tolerance and Ease of Use of Wilbo's Blends+ (Commercial Enteral Feed Based on Real Food) When Used as Part of a Dietitian Prescribed Enteral Feeding Plan

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-16
Completion: 2026-03-30
Conditions
Enteral Nutrition (Food for Special Medical Purposes) Enteral Feeds Enteral Tube Nutrition Gastrostomy Tube
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07034469 | NOT_YET_RECRUITING | NA
150 Participants

Air Tamponade Versus Fluorinated Gas Tamponade for Rhegmatogenous Retinal Detachment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-03-20
Completion: 2029-03-20
Conditions
Retinal Detachment Rhegmatogenous
Interventions
PROCEDURE
No Results Yet
NCT07033416 | RECRUITING | NA
60 Participants

A Trial Of Approach Bias Modification Training During Treatment For Cocaine Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-03-31
Completion: 2026-10-31
Conditions
Training for Cocaine Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT07031934 | COMPLETED
114 Participants

Investigation of the Relationships Between Core Muscle Endurance, Pelvic Oscillations and Pelvic Width in Athletes and Sedentaries

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-25
Completion: 2025-06-30
Conditions
Core Muscle Endurance Athlete Sedentary
No Results Yet
NCT07029191 | COMPLETED | NA
12 Participants

Screening for Alterations in the Autonomic Nervous System

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-21
Completion: 2025-12-12
Conditions
Dysautonomia ACCUVEIN Superficial Veins Sympathetic Nervous System Standing Test
Interventions
OTHER
No Results Yet
NCT07027891 | RECRUITING | NA
4670 Participants

The Rule-Out Acute Myocardial Infarction Using Aritifical Intelligence Electrocardiogram (ROMIAE) 2 Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-01
Completion: 2027-12-30
Conditions
Myocardial Infarction (MI) Chest Pain Rule Out Myocardial Infarction
Interventions
DEVICE
No Results Yet
NCT07025720 | RECRUITING | NA
25 Participants

Personalized Accelerated TMS for High-Risk Adolescent Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-01
Completion: 2027-04-30
Conditions
Suicidal Ideation Major Depressive Disorder (MDD)
Interventions
DEVICE
No Results Yet
NCT07025538 | RECRUITING | PHASE1
42 Participants

Biomarker-Guided Ruxolitinib for the Prevention of Chronic Graft Versus Host Disease After Allogeneic Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-09
Completion: 2028-04-05
Conditions
Hematopoietic and Lymphatic System Neoplasm
Interventions
OTHER PROCEDURE DRUG
No Results Yet
NCT07024498 | NOT_YET_RECRUITING | NA
3492 Participants

Coordinating Outpatient bupreNorphiNe for Emergency Care and Continuing Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-01
Completion: 2029-05-01
Conditions
Opioid Use Disorder
Interventions
OTHER
No Results Yet
NCT07024316 | RECRUITING | PHASE1/PHASE2
6 Participants

A Study to Investigate the Improvement of Photosensitivity in Terms of Skin Lesions Associated With CEP Following Administration of Oral ATL-001 (Ciclopirox Oral Solution) in Participants Aged >18 Years of Age With CEP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-15
Completion: 2027-10-01
Conditions
Congenital Erythropoietic Porphyria (CEP)
Interventions
DRUG
No Results Yet
NCT07023302 | RECRUITING | PHASE3
123 Participants

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants in Japan With Alopecia Areata

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-19
Completion: 2029-02-28
Conditions
Alopecia Areata
Interventions
DRUG
No Results Yet
NCT07020520 | RECRUITING | NA
60 Participants

EvaluatioN of Optilume Drug-Coated Balloon for the Endoscopic Treatment of UREteric Strictures

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-01
Completion: 2027-02-28
Conditions
Ureteral Stricture
Interventions
DEVICE
No Results Yet
NCT07018856 | RECRUITING
120 Participants

Feasibility Study of Novice-Performed Lung Ultrasound for Pneumothorax Detection After Cardiac Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-16
Completion: 2026-09-30
Conditions
Pneumothorax Cardiac Surgery Lung Ultrasound Chest Tube Removal Postoperative Complications (Cardiopulmonary)
No Results Yet
NCT07018596 | NOT_YET_RECRUITING | NA
215 Participants

NS-PFA Catheter Ablation of Paroxysmal Atrial Fibrillation With the Pulse Biosciences CellFX System

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2026-10-31
Conditions
Atrial Fibrillation Paroxysmal Cardiac Ablation Cardiac Arrhythmia
Interventions
DEVICE
No Results Yet
NCT07001319 | RECRUITING | PHASE1
30 Participants

Study of GS-3242 in Participants With HIV-1; Substudy-05

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-29
Completion: 2025-12-31
Conditions
HIV-1-infection
Interventions
DRUG
No Results Yet
NCT06998524 | RECRUITING | PHASE3
75 Participants

A Study to Assess the Efficacy and Safety of Emicizumab in Participants With Type 3 Von Willebrand Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-27
Completion: 2027-03-30
Conditions
Von Willebrand Disease, Type 3
Interventions
DRUG
No Results Yet
NCT06992245 | RECRUITING | NA
40 Participants

Characterization of Placental Diffusion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-06
Completion: 2027-12-31
Conditions
Pregnancy in Diabetic Placenta Diseases
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06991803 | COMPLETED | NA
132 Participants

Effects of Different Irrigation Activation Techniques on the Healing of Large Periapical Lesions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-01
Completion: 2024-06-30
Conditions
Periapical Periodontitis Irrigation Activation Lasers
Interventions
OTHER
NCT06991114 | RECRUITING | PHASE2
90 Participants

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-09
Completion: 2028-01-31
Conditions
Refractory Rheumatoid Arthritis (RA) Idiopathic Inflammatory Myopathies (IIMs) Systemic Sclerosis (SSc) Rheumatoid Arthritis (RA IIM Myositis Scleroderma Sjogren Syndrome Sjogrens Disease
Interventions
DRUG
No Results Yet
NCT06977503 | NOT_YET_RECRUITING | NA
40 Participants

Electrotherapy Stimulation Together With Life Coaching for the Support of Burnout Symptoms in Healthcare Workers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2026-10-15
Conditions
Psychiatric Disorder
Interventions
PROCEDURE OTHER BEHAVIORAL
No Results Yet
NCT06975735 | COMPLETED | NA
108 Participants

Does the TAP Block Work Better Than the TFP Block for Relieving Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-25
Completion: 2025-12-15
Conditions
Pain
Interventions
PROCEDURE
No Results Yet
NCT06975046 | RECRUITING | NA
365 Participants

Aerodynamic Measurements in the Pediatric Population

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-12-22
Completion: 2030-12-31
Conditions
Normal Voice
Interventions
DEVICE
No Results Yet
NCT06972147 | RECRUITING
40 Participants

Prevalence and Description of FIRE (Food Induced Immediate Response of the Esophagus) in the Pediatric Population With Eosinophilic Esophagitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-01
Completion: 2026-05-01
Conditions
Eosinophilic Esophagitis
No Results Yet
NCT06969287 | NOT_YET_RECRUITING | PHASE3
46 Participants

Mitigating Delirium With Fluvoxamine Treatment for Non-Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2027-04-01
Conditions
Delirium Surgery-Complications
Interventions
DRUG
No Results Yet
NCT06968195 | SUSPENDED | PHASE1
24 Participants

Autologous CAR T Cells Targeting GPC3 (RPCAR01) for the Treatment of Advanced or Metastatic GPC3 Expressing Hepatocellular Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-30
Completion: 2028-05-30
Conditions
Advanced Hepatocellular Carcinoma Metastatic Hepatocellular Carcinoma Recurrent Hepatocellular Carcinoma Refractory Hepatocellular Carcinoma Stage III Hepatocellular Carcinoma AJCC v8 Stage IV Hepatocellular Carcinoma AJCC v8
Interventions
BIOLOGICAL PROCEDURE DRUG
No Results Yet
NCT06966323 | RECRUITING
150 Participants

Hold me Tight/Let me Go: Effectiveness of a Course to Enhance Parent-adolescent Relationship

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-11
Completion: 2028-02-01
Conditions
Parent Training Parent Child Relationship Parent-child Problem
Interventions
BEHAVIORAL
No Results Yet
NCT06962280 | RECRUITING | PHASE3
465 Participants

A Long-Term Study of Tirzepatide (LY3298176) in Adults With Type 1 Diabetes and Obesity or Overweight

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-12
Completion: 2027-04-30
Conditions
Type 1 Diabetes Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06952530 | RECRUITING | PHASE3
487 Participants

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-30
Completion: 2027-09-30
Conditions
Hypertension
Interventions
DRUG
No Results Yet
NCT06948435 | RECRUITING | PHASE3
487 Participants

A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-30
Completion: 2027-09-30
Conditions
Hypertension Overweight or Obesity
Interventions
DRUG
No Results Yet
NCT06945419 | RECRUITING | PHASE1
201 Participants

A Study of LY4086940 in Healthy Participants and Participants With Overweight or Obesity, With or Without Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-23
Completion: 2026-04-30
Conditions
Healthy Overweight Obesity Type 2 Diabetes
Interventions
DRUG
No Results Yet
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