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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06853860 | COMPLETED | NA
70 Participants

Effects of Hand Massage Applied With Two Different Methods

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-15
Completion: 2025-05-15
Conditions
Angiopathy, Peripheral Pain, Acute Reflexology
Interventions
OTHER
No Results Yet
NCT06853158 | RECRUITING | NA
90 Participants

MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-02
Completion: 2027-01-31
Conditions
Sickle Cell Disease
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06851559 | RECRUITING | PHASE2
80 Participants

A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-10-30
Completion: 2026-12-31
Conditions
Eosinophilic Esophagitis
Interventions
DRUG
No Results Yet
NCT06849947 | NOT_YET_RECRUITING | PHASE2
272 Participants

Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2031-06-30
Conditions
Breast Cancer Metastatic
Interventions
DRUG
No Results Yet
NCT06848348 | RECRUITING | PHASE2
200 Participants

Efficacy and Safety Study of Halneuron in the Treatment of Chemotherapy-Induced Neuropathic Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-21
Completion: 2026-07-31
Conditions
Chemotherapy Induced Neuropathic Pain
Interventions
DRUG
No Results Yet
NCT06847854 | RECRUITING | PHASE1
176 Participants

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7497372 in Participants With Diabetic Macular Edema (DME)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-12-08
Completion: 2027-02-28
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
NCT06844318 | RECRUITING
153 Participants

Impact of IBD Activity on Frailty in Patients Over 60 Years

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-14
Completion: 2026-04-30
Conditions
IBD
No Results Yet
NCT06843252 | RECRUITING | NA
16 Participants

Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-02
Completion: 2026-12-31
Conditions
Huntington Disease
Interventions
DEVICE
No Results Yet
NCT06841874 | NO_LONGER_AVAILABLE

Expanded Access Program of Taletrectinib in Patients With Advanced or Metastatic ROS1-Positive NSCLC

Study Type: EXPANDED_ACCESS
Last Updated: 2025-12-24
Conditions
Bronchogenic Carcinoma Lung Neoplasms Respiratory Tract Neoplasms Thoracic Neoplasms Neoplasms by Site Neoplasms Lung Diseases Respiratory Tract Diseases Carcinoma Non Small Cell Carcinoma of the Lung ROS1-positive Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
NCT06841354 | RECRUITING | PHASE3
1000 Participants

A Study of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Triple-Negative Breast Cancer (MK-2870-011/TroFuse-011)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-03-16
Completion: 2030-05-18
Conditions
Triple Negative Breast Neoplasms
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06839235 | RECRUITING | PHASE1/PHASE2
23 Participants

Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-16
Completion: 2029-03-31
Conditions
Primary Hyperoxaluria Type 1 (PH1)
Interventions
DRUG
No Results Yet
NCT06834347 | RECRUITING | PHASE3
210 Participants

A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-12
Completion: 2027-01-08
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG
No Results Yet
NCT06831552 | RECRUITING | NA
84 Participants

Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-30
Completion: 2029-06-01
Conditions
Neuroblastoma High-risk Neuroblastoma
Interventions
BEHAVIORAL
No Results Yet
NCT06830759 | RECRUITING
700 Participants

Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-03-28
Completion: 2031-09-30
Conditions
Diffuse Large B-cell Lymphoma Follicular Lymphoma
No Results Yet
NCT06830720 | RECRUITING
3250 Participants

A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-20
Completion: 2030-06-30
Conditions
Breast Neoplasms
Interventions
DRUG
No Results Yet
NCT06827457 | COMPLETED | PHASE1
58 Participants

A Study of Safety, Tolerability, PK, and PD of Subcutaneous GenSci120 in Healthy Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-20
Completion: 2025-11-27
Conditions
Autoimmune Disease
Interventions
DRUG
No Results Yet
NCT06825702 | RECRUITING | PHASE2
28 Participants

Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-01
Completion: 2026-11-30
Conditions
Macular Edema
Interventions
DRUG
No Results Yet
NCT06822426 | RECRUITING | PHASE3
200 Participants

Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-14
Completion: 2027-01-31
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
DRUG
No Results Yet
NCT06820957 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
437 Participants

Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-10
Completion: 2032-07-15
Conditions
CIC-Rearranged Sarcoma Metastatic Ewing Sarcoma Metastatic High Grade Sarcoma Metastatic Undifferentiated Round Cell Sarcoma Metastatic Undifferentiated Sarcoma, Not Otherwise Specified Round Cell Sarcoma With EWSR1-non-ETS Fusion Sarcoma With BCOR Genetic Alterations
Interventions
PROCEDURE DRUG OTHER RADIATION
No Results Yet
NCT06817512 | ACTIVE_NOT_RECRUITING | NA
190 Participants

Ischemic Stroke Nutrition Intervention Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-03-23
Completion: 2027-01-15
Conditions
Ischemic Stroke
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06817356 | RECRUITING | PHASE2
300 Participants

A Study to Evaluate Mazdutide Compared With Placebo in Participants With Alcohol Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-06
Completion: 2026-08-31
Conditions
Alcohol Use Disorder
Interventions
DRUG
No Results Yet
NCT06814743 | COMPLETED | NA
107 Participants

A Mobile Application for Female Athletes With Pelvic Floor Dysfunctions (ACTITUD2.0)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-10
Completion: 2025-06-30
Conditions
Pelvic Floor Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT06810505 | RECRUITING | PHASE3
420 Participants

A Study of Oral Atogepant Tablets to Assess Adverse Events and Change in Disease Activity To Prevent Migraine in Participants Aged 12 to 17 Years

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-13
Completion: 2031-03-31
Conditions
Chronic Migraine
Interventions
DRUG
No Results Yet
NCT06807580 | RECRUITING | PHASE2
40 Participants

Progesterone in Gender Affirming Hormone Therapy Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-12
Completion: 2027-02-28
Conditions
Transgender Women
Interventions
DRUG
No Results Yet
NCT06803602 | ENROLLING_BY_INVITATION | NA
2100 Participants

HIFEM Technology for Post-Radical Prostatectomy and Post-Holmium Laser Prostate Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-01
Completion: 2027-03-31
Conditions
Holmium Laser Prostate Surgery Radical Prostatectomy
Interventions
DEVICE
No Results Yet
NCT06798012 | RECRUITING | PHASE2
36 Participants

A Study of TAK-411 in Adults With Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-14
Completion: 2027-12-02
Conditions
Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP)
Interventions
BIOLOGICAL
No Results Yet
NCT06795893 | RECRUITING
240 Participants

The Anifrolumab PRIM Program

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-11-07
Completion: 2031-04-15
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
NCT06791512 | RECRUITING | PHASE3
166 Participants

mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-01-18
Completion: 2030-12-31
Conditions
Colorectal Cancer (CRC) pMMR/MSS Adenocarcinoma of the Colon or Rectum
Interventions
DRUG
No Results Yet
NCT06791291 | RECRUITING | PHASE2
10 Participants

Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-07-25
Completion: 2028-03-06
Conditions
Type 1 Diabetes Mellitus
Interventions
DRUG
No Results Yet
NCT06784466 | RECRUITING | NA
360 Participants

Coherent Sine Burst Electroporation (CSE) Ablation System US IDE Study for Patients With Atrial Fibrillation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-09-10
Completion: 2027-06-30
Conditions
Atrial Fibrillation (AF) Persistant Atrial Fibrillation Paroxysmal AF
Interventions
DEVICE
No Results Yet
NCT06782516 | ENROLLING_BY_INVITATION | NA
1687 Participants

Native-RISE (Risk Identification for Suicide and Enhanced Care)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-02-01
Completion: 2029-09-30
Conditions
Suicide Prevention
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT06780137 | RECRUITING | PHASE1/PHASE2
242 Participants

A Study to Evaluate the Safety and Efficacy of Gocatamig (MK-6070) and Ifinatamab Deruxtecan (I-DXd) in Participants With Relapsed/Refractory Extensive-Stage Small Cell Lung Cancer (MK-6070-002)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-02-27
Completion: 2029-08-31
Conditions
Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
NCT06780098 | RECRUITING | PHASE2
144 Participants

Substudy 01I: A Study of Investigational Agents in Participants With Previously Treated Stage IV Squamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01I/KEYMAKER-U01I)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-28
Completion: 2032-03-02
Conditions
Lung Neoplasm
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06780085 | RECRUITING | PHASE2
96 Participants

A Study of Investigational Agents in Participants With Previously Treated Stage IV Nonsquamous Non-small Cell Lung Cancer (NSCLC) (MK-3475-01H/KEYMAKER-U01)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-05-13
Completion: 2032-03-12
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06772675 | RECRUITING | NA
13 Participants

Vancomycin Reduction Practices (VRP) in the NICU

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-02
Completion: 2027-09-30
Conditions
Antibiotic Stewardship Neonatal Sepsis, Late-Onset Vancomycin
Interventions
BEHAVIORAL
No Results Yet
NCT06770985 | RECRUITING
1000 Participants

Effectiveness of Artificial Intelligence Algorithms

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-01-08
Completion: 2025-07-15
Conditions
Artificial Intelligence (AI)
Interventions
OTHER
No Results Yet
NCT06770972 | RECRUITING | NA
40 Participants

Family Foundations for Individuals Pregnant Via ART

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-06-11
Completion: 2026-12-31
Conditions
Assisted Reproductive Technology
Interventions
BEHAVIORAL
No Results Yet
NCT06768489 | RECRUITING | PHASE1
140 Participants

A Study of JNJ-79635322 in Combination With Daratumumab With or Without Lenalidomide or in Combination With Pomalidomide for Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-04
Completion: 2027-11-19
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06764693 | RECRUITING
1200 Participants

An Ex-US Study to Assess Treatment Persistence With Risankizumab in Adult Participants With Psoriatic Arthritis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2025-01-31
Completion: 2029-02-28
Conditions
Psoriatic Arthritis
No Results Yet
NCT06752603 | RECRUITING | PHASE2
50 Participants

A Clinical Study of ONO-1110 in Patients With Hunner Type Interstitial Cystitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2025-04-02
Completion: 2026-06-30
Conditions
Hunner Type Interstitial Cystitis
Interventions
DRUG
No Results Yet
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