Clinical Trials
Showing trials with last updates posted in 2025.
666
Participants
Evaluation of Selective and Stepwise Excavation in Young Permanent Teeth With Deep Caries Lesions.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-09-01
Completion:
2028-09-01
Conditions
Dental Caries
Dental Cavities
Interventions
PROCEDURE
No Results Yet
142
Participants
Integrating SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-24
Completion:
2025-12-18
Conditions
Disease and Dysfunction
Functional Fitness Deterioration
Activities of Daily Living
Instrumental Activities of Daily Living
Sleep Quality
Interventions
OTHER
No Results Yet
680
Participants
Effectiveness of Integrated Network for Student Psychosocial Intervention, Resilience, and Education (INSPIRE) on Mental Health Outcomes Among Indonesian Adolescents in Bandung
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2026-02-16
Conditions
Adolescents
Health Knowledge
Mental Health
Health Literacy
Resilience
Depression
Anxiety
Parents
School Intervention
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-28
Completion:
2025-10-05
Conditions
Cardiovascular Diseases (CVD)
Coronary Heart Disease (CHD)
Heart Failure
Congenital Heart Disease
No Results Yet
142
Participants
Using SPOZ Technology to Support and Enhance the Vitality Acupunch (VA) Exercise Program for Older Adults With Dementia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-23
Completion:
2025-12-18
Conditions
Cognitive and Behavioral Impairment
Sensory and Perceptual Impairment
Interventions
OTHER
No Results Yet
30
Participants
Miro3D Wound Matrix Study for Diabetic Foot Ulcers and Wound Healing
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-01
Completion:
2026-07-31
Conditions
Diabetic Foot Ulcers (DFUs)
Chronic Wound of the Lower Limb (Leg Ulcer or Foot Ulcer)
Interventions
DEVICE
OTHER
No Results Yet
20
Participants
Study of Miro3D Wound Matrix for Healing Wounds and Ulcers in Outpatient Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-29
Completion:
2025-12-31
Conditions
Diabetic Foot Ulcers (DFUs)
Venous Leg Ulcers (VLUs)
Pressure Ulcers
Surgical Wound Dehiscence (SWD)
Chronic Wounds
Undermined and Tunneling Wounds
Interventions
DEVICE
No Results Yet
An Expanded Access Study to Assess Treprostinil Palmitil Inhalation Powder (TPIP) for Participants With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Pulmonary Arterial Hypertension
Pulmonary Hypertension, Interstitial Lung Disease
Interventions
DRUG
No Results Yet
16
Participants
Investigating the Acute Effects of Increasing Glucagon Exposure in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-31
Completion:
2025-09-19
Conditions
Glucose Metabolism
Glucagon
Interventions
OTHER
No Results Yet
42
Participants
A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-09
Completion:
2027-11-30
Conditions
Metabolic Dysfunction-Associated Steatohepatitis
Interventions
DRUG
No Results Yet
92
Participants
FLASH-Breast: Evaluating the Efficacy of Fezolinetant in Reducing Vasomotor Symptoms in Women With Breast Cancer on Endocrine Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-12-05
Completion:
2028-03-31
Conditions
Breast Cancer Early Stage Breast Cancer (Stage 1-3)
Interventions
DRUG
No Results Yet
72
Participants
A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD5492 in Adult Participants With Systemic Lupus Erythematosus or Idiopathic Inflammatory Myopathies or Rheumatoid Arthritis.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-01
Completion:
2027-06-22
Conditions
Systemic Lupus Erythematosus
Idiopathic Inflammatory Myopathies
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
905
Participants
A Study of Tirzepatide (LY3298176) Compared With Placebo in Adults With Type 1 Diabetes and Obesity or Overweight
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-25
Completion:
2027-05-31
Conditions
Type 1 Diabetes
Obesity
Overweight
Interventions
DRUG
No Results Yet
60
Participants
Safety of a Single, Intravitreal Injection of 8.8M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-20
Completion:
2026-09-30
Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL
OTHER
No Results Yet
6000
Participants
Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-23
Completion:
2029-10-31
Conditions
Percutaneous Coronary Intervention
Peripheral Endovascular Intervention
Interventions
DRUG
No Results Yet
100
Participants
Capillary Leak Index as a Prognostic Indicator for Post-Operative Abdominal Sepsis in Critically Ill Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-04
Completion:
2025-08-01
Conditions
Intra-Abdominal Infections
Intestinal Obstruction
Appendicitis Acute
Perforated Viscus
240
Participants
A Study of LY3457263 Compared With Placebo in Participants With Type 2 Diabetes on a Stable Dose of Semaglutide or Tirzepatide
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-28
Completion:
2026-12-31
Conditions
Type 2 Diabetes
Interventions
DRUG
No Results Yet
420
Participants
Study of Daraxonrasib (RMC-6236) in Patients With RAS Mutated NSCLC (RASolve 301)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-06
Completion:
2027-12-01
Conditions
NSCLC (Non-small Cell Lung Cancer)
Non-Small Cell Lung Cancer
NSCLC
NSCLC (Non-small Cell Lung Carcinoma)
NSCLC (Advanced Non-small Cell Lung Cancer)
Interventions
DRUG
No Results Yet
3375
Participants
Shield Post-Approval Study Protocol
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-07-14
Completion:
2030-09-01
Conditions
Colo-rectal Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
60
Participants
Evaluation of the Efficacy of Laser Acupuncture on Uremic Pruritus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-04-09
Completion:
2024-05-11
Conditions
Uremia
Interventions
DEVICE
26
Participants
Genetically Engineered Cells (CD83 CAR T Cells) for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-15
Completion:
2028-04-01
Conditions
Recurrent Acute Myeloid Leukemia
Refractory Acute Myeloid Leukemia
Interventions
DRUG
PROCEDURE
OTHER
No Results Yet
44
Participants
Study of Remibrutinib (LOU064) Efficacy and Safety and Exploration of Its Mechanism of Action in Participants With Chronic Urticaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-22
Completion:
2027-09-01
Conditions
Chronic Urticaria (CU): Chronic Inducible Urticaria (CINDU) and Chronic Spontaneous Urticaria (CSU)
Interventions
DRUG
No Results Yet
206
Participants
A Study to Investigate Tonlamarsen for the Treatment of Adults With Uncontrolled Hypertension (KARDINAL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-10
Completion:
2026-01-09
Conditions
Hypertension
Interventions
DRUG
No Results Yet
200
Participants
A Study to Investigate Effectiveness of Tirzepatide Following Initiation of Ixekizumab in Participants With Active Psoriatic Arthritis and Overweight or Obesity in Clinical Practice (TOGETHER AMPLIFY-PsA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-06
Completion:
2027-11-30
Conditions
Psoriatic Arthritis
Overweight or Obesity
Interventions
DRUG
No Results Yet
70
Participants
Effects of Hand Massage Applied With Two Different Methods
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-15
Completion:
2025-05-15
Conditions
Angiopathy, Peripheral
Pain, Acute
Reflexology
Interventions
OTHER
No Results Yet
90
Participants
MULTIsite Feasibility of MUSIc Therapy to Address Quality Of Life in Sickle Cell Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-02
Completion:
2027-01-31
Conditions
Sickle Cell Disease
Interventions
BEHAVIORAL
OTHER
No Results Yet
80
Participants
A Study in Adult Participants With EoE to Evaluate Vonoprazan 20 mg Compared to Placebo After 12 Weeks and to Evaluate Vonoprazan 20 mg Up to 24 Weeks
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-30
Completion:
2026-12-31
Conditions
Eosinophilic Esophagitis
Interventions
DRUG
No Results Yet
272
Participants
Fulvestrant With Ribociclib Versus Physician's Choice Treatments Recurred After Completion of Adjuvant Cyclin-Dependent Kinase 4/6 Inhibitors in HR+, HER2- Metastatic Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-01
Completion:
2031-06-30
Conditions
Breast Cancer Metastatic
Interventions
DRUG
No Results Yet
153
Participants
Impact of IBD Activity on Frailty in Patients Over 60 Years
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-14
Completion:
2026-04-30
Conditions
IBD
No Results Yet
16
Participants
Home-based TDCS (Transcranial Direct Current Stimulation) for Cognitive and Behavioral Symptoms in Huntington's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-09-02
Completion:
2026-12-31
Conditions
Huntington Disease
Interventions
DEVICE
No Results Yet
Expanded Access Program of Taletrectinib in Patients With Advanced or Metastatic ROS1-Positive NSCLC
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Bronchogenic Carcinoma
Lung Neoplasms
Respiratory Tract Neoplasms
Thoracic Neoplasms
Neoplasms by Site
Neoplasms
Lung Diseases
Respiratory Tract Diseases
Carcinoma
Non Small Cell Carcinoma of the Lung
ROS1-positive Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG
No Results Yet
23
Participants
Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-06-16
Completion:
2029-03-31
Conditions
Primary Hyperoxaluria Type 1 (PH1)
Interventions
DRUG
No Results Yet
210
Participants
A Phase 3 Study to Assess the Efficacy, Safety, and Tolerability of Itepekimab (Anti-IL-33 mAb) in Participants With Inadequately-controlled Chronic Rhinosinusitis With Nasal Polyps
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-12
Completion:
2027-01-08
Conditions
Chronic Rhinosinusitis With Nasal Polyps
Interventions
DRUG
No Results Yet
84
Participants
Resource Intervention to Support Equity (RISE) in High-Risk Neuroblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-04-30
Completion:
2029-06-01
Conditions
Neuroblastoma
High-risk Neuroblastoma
Interventions
BEHAVIORAL
No Results Yet
700
Participants
Real-World Study to Assess Subcutaneous Epcoritamab in Adult Participants With Diffuse Large B-Cell and Follicular Lymphoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-03-28
Completion:
2031-09-30
Conditions
Diffuse Large B-cell Lymphoma
Follicular Lymphoma
No Results Yet
3250
Participants
A Non-interventional Study for Kisqali (Ribociclib) in Combination With an Aromatase Inhibitor for Adjuvant Treatment in Patients With HR+/HER2- Early Breast Cancer at High Risk of Recurrence
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-20
Completion:
2030-06-30
Conditions
Breast Neoplasms
Interventions
DRUG
No Results Yet
58
Participants
A Study of Safety, Tolerability, PK, and PD of Subcutaneous GenSci120 in Healthy Adults.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-20
Completion:
2025-11-27
Conditions
Autoimmune Disease
Interventions
DRUG
No Results Yet
28
Participants
Safety, Tolerability and Efficacy of Intravitreal KIO-104 in Patients With Macular Edema
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-01
Completion:
2026-11-30
Conditions
Macular Edema
Interventions
DRUG
No Results Yet
200
Participants
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-05-14
Completion:
2027-01-31
Conditions
Central Line Associated Blood Stream Infections (CLABSI)
Interventions
DRUG
No Results Yet
437
Participants
Testing a New Combination of Anti-cancer Drugs in Patients Newly Diagnosed With Ewing Sarcoma Who Have Cancer That Has Spread to Other Parts of the Body
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-11-10
Completion:
2032-07-15
Conditions
CIC-Rearranged Sarcoma
Metastatic Ewing Sarcoma
Metastatic High Grade Sarcoma
Metastatic Undifferentiated Round Cell Sarcoma
Metastatic Undifferentiated Sarcoma, Not Otherwise Specified
Round Cell Sarcoma With EWSR1-non-ETS Fusion
Sarcoma With BCOR Genetic Alterations
Interventions
PROCEDURE
DRUG
OTHER
RADIATION
No Results Yet
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