Clinical Trials
Showing trials with last updates posted in 2025.
158
Participants
A Study to Evaluate ALN-BCAT in Patients With Hepatocellular Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-30
Completion:
2027-09-30
Conditions
Advanced Hepatocellular Carcinoma
Metastatic Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
25
Participants
A Study of RhinAer Stylus for Treating Chronic Rhinitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-03
Completion:
2025-12-31
Conditions
Chronic Rhinitis
Interventions
DEVICE
No Results Yet
140
Participants
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-10
Completion:
2027-12-31
Conditions
Ulcerative Colitis
Ulcerative Colitis Chronic
Interventions
DRUG
No Results Yet
[Trial of device that is not approved or cleared by the U.S. FDA]
Last Updated:
2025-12-24
No Results Yet
244
Participants
An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-11
Completion:
2029-01-31
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
54
Participants
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-14
Completion:
2028-07-05
Conditions
Huntington's Disease
Interventions
DRUG
No Results Yet
286
Participants
Enhancing Uptake of Preconception Care Services in Family Practice Clinics Using a Patient Centered Screening Tool
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-23
Completion:
2025-08-26
Conditions
Women
Reproductive Age
Interventions
OTHER
No Results Yet
100
Participants
Prospective Evaluation Of Delayed Effects Of Pediatric Car T Cell Therapy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-31
Completion:
2027-03-31
Conditions
B-ALL
Hematologic Malignancy
Solid Tumor
No Results Yet
24
Participants
Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-02
Completion:
2028-09-01
Conditions
Cutaneous Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
27
Participants
Self-efficacy-based Auditory Rehabilitation With Over-the-Counter Hearing Aids
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-30
Completion:
2026-01-31
Conditions
Hearing Loss, Sensorineural
Interventions
DEVICE
No Results Yet
261
Participants
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUSâ„¢) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-03
Completion:
2026-02-28
Conditions
Hypertension
Interventions
DEVICE
OTHER
No Results Yet
28
Participants
Bilateral vs. Unilateral Neuromobilization in Carpal Tunnel Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-08-31
Completion:
2025-05-30
Conditions
Carpal Tunnel Syndrome
Interventions
OTHER
No Results Yet
1000
Participants
Observational Study of Oral Atogepant to Evaluate Real-World Effectiveness in Adult Participants With Migraine
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-26
Completion:
2029-02-28
Conditions
Migraine
No Results Yet
123
Participants
Advanced Mutidimensional and Ultra High Resolution Computed Tomography to Inspect Cardiopulmonary Involvement in Progressive Fibrosing Interstitial Lung Diseases
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-01
Completion:
2025-09-01
Conditions
Interstitial Lung Diseases
No Results Yet
1000
Participants
Lung Cancer Screening Program in Mexico
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2022-03-24
Completion:
2026-03-24
Conditions
Lung Cancer
Interventions
OTHER
No Results Yet
50
Participants
Accelerated Brachytherapy Forward Chemo Radiation Therapy (ABC-RT) for Locally-advanced Cervical Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-02-11
Completion:
2031-12-31
Conditions
Locally Advanced Cervical Carcinoma
Interventions
RADIATION
DRUG
No Results Yet
0
Participants
Metformin and Vascular Function in Prediabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-13
Completion:
2025-12-01
Conditions
PreDiabetes
Interventions
DRUG
OTHER
No Results Yet
40
Participants
Improving Executive Function in Korean Children With Autism
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-11
Completion:
2026-03-15
Conditions
Autism Spectrum Disorder
Interventions
BEHAVIORAL
No Results Yet
3000
Participants
Differentiation of Benign and Malignant Pulmonary Nodules by Volatile Organic Compounds in Human Exhaled Breath
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-30
Completion:
2026-12-30
Conditions
Pulmonary Nodules, Multiple
Pulmonary Nodules, Solitary
Lung Cancer
Interventions
OTHER
No Results Yet
60
Participants
Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-01-03
Completion:
2026-02-15
Conditions
Obesity
Bariatric Surgery
Laparoscopic Sleeve Gastrectomy
Acute Post Operative Pain
Interventions
PROCEDURE
No Results Yet
57
Participants
AZD4205 in Relapsed or Refractory Peripheral T Cell Lymphoma (JACKPOT27)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-05-31
Completion:
2025-10-17
Conditions
Peripheral T Cell Lymphoma
Interventions
DRUG
No Results Yet
3600
Participants
Optimizing Care in Critically Ill at UCHealth by Liberalizing the Target O2 in Mechanically-ventilated ICU Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-01
Completion:
2026-06-30
Conditions
Respiratory Failure
Acute Hypoxemic Respiratory Failure
Acute Hypoxic Respiratory Failure
Hypoxemia
Hypoxia
Hypoxic Respiratory Failure
Interventions
OTHER
BEHAVIORAL
No Results Yet
84
Participants
A Study to Evaluate the Efficacy and Safety of Frexalimab, Brivekimig, or Rilzabrutinib in Participants Aged 16 to 75 Years With Primary Focal Segmental Glomerulosclerosis or Minimal Change Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-19
Completion:
2026-12-23
Conditions
Focal Segmental Glomerulosclerosis
Glomerulonephritis Minimal Lesion
Interventions
DRUG
No Results Yet
4220
Participants
A Study of Elacestrant Versus Standard Endocrine Therapy in Women and Men With ER+,HER2-, Early Breast Cancer With High Risk of Recurrence
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-27
Completion:
2029-08-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
16
Participants
Comparison of HRS-5965 Capsules and Tablets in Healthy Subjects
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-17
Completion:
2024-08-06
Conditions
Paroxysmal Nocturnal Hemoglobinuria，IgA Nephropathy
Interventions
DRUG
No Results Yet
12
Participants
A Study to Evaluate the Safety, Pharmacokinetics, and Activity of RO7759065 as a Single Agent and in Combination With Atezolizumab in Patients With Locally Advanced or Metastatic Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-16
Completion:
2025-11-05
Conditions
Solid Tumour
Interventions
DRUG
No Results Yet
160
Participants
Kesimpta (Ofatumumab) in Greek Multiple Sclerosis Patients - an Observational Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-10
Completion:
2028-12-30
Conditions
Relapsing Multiple Sclerosis (RMS)
Interventions
OTHER
No Results Yet
188
Participants
Prognostic Value of Measuring CtDNA in a Cohort of Patients With Stage III and IV Upper Aero-digestive Tract (UADT) Cancer , Treated With Curative RADiOtherapy With or Without Concomitant Treatment.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-30
Completion:
2026-09-30
Conditions
SCC - Squamous Cell Carcinoma
Upper Aero-digestive Tract (UADT) Neoplasm
Interventions
OTHER
No Results Yet
41
Participants
Evaluation of Clinical Outcomes of Scaffold Treatment of Partial Meniscal Injuries of the Knee
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-17
Completion:
2025-07-31
Conditions
Knee Osteoarthritis
Knee Injuries
Meniscus Lesion
Interventions
OTHER
No Results Yet
170
Participants
A Study of JNJ-88998377 for Relapsed/Refractory B-cell Non-Hodgkin's Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-05-28
Completion:
2027-10-29
Conditions
Lymphoma, Non-Hodgkin
Refractory B-Cell NHL
Relapsed B-cell NHL
Interventions
DRUG
No Results Yet
10742
Participants
Effectiveness of Two Aspirin Doses for Prevention of Hypertensive Disorders of Pregnancy: ASPIRIN TRIAL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-18
Completion:
2029-01-01
Conditions
Hypertensive Disorders of Pregnancy
Preeclampsia
Gestational Hypertension
Interventions
DRUG
No Results Yet
1850
Participants
Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2024-06-25
Completion:
2031-12-29
Conditions
Transthyretin Amyloidosis
ATTR-CM
ATTRv-PN
ATTR
ATTR-Mixed
hATTR
Interventions
DRUG
No Results Yet
40
Participants
Sapanisertib and Serabelisib (PIKTOR) With Paclitaxel and a Substudy With an Insulin-Suppressing Diet in Patients With Advanced/Recurrent Endometrial Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-12-12
Completion:
2028-09-30
Conditions
Endometrial Cancer
Interventions
DRUG
No Results Yet
95
Participants
Clinical Performance Evaluation of Two Frequent Replacement Silicone Hydrogel Multifocal Toric Contact Lenses
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-26
Completion:
2024-12-31
Conditions
Presbyopia
Astigmatism
Interventions
DEVICE
686
Participants
A Study to Compare Sacituzumab Tirumotecan (MK-2870) Monotherapy Versus Treatment of Physician's Choice as Second-line Treatment for Participants With Recurrent or Metastatic Cervical Cancer (MK-2870-020/TroFuse-020/Gog-3101/ENGOT-cx20)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-24
Completion:
2028-06-15
Conditions
Cervical Cancer
Interventions
BIOLOGICAL
DRUG
No Results Yet
300
Participants
Bomedemstat vs Hydroxyurea for Essential Thrombocythemia (MK-3543-007)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-16
Completion:
2027-09-28
Conditions
Essential Thrombocythemia
Interventions
DRUG
No Results Yet
170
Participants
The Genetics Navigator: Evaluating a Digital Platform for Genomics Health Services
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-10-28
Completion:
2027-03-31
Conditions
Cardiac Conditions
Connective Tissue Diseases
Retinal Disease
Epilepsy in Children
Neurodevelopmental Disorders
Cancer
Polyposis
Interventions
BEHAVIORAL
No Results Yet
42
Participants
Providing Evidence-Based Approaches for Caregiver Stress Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-02
Completion:
2025-12-19
Conditions
Caregiving Stress
Dementia
Interventions
OTHER
No Results Yet
915
Participants
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-07-11
Completion:
2026-10-31
Conditions
Chronic Spontaneous Urticaria
Interventions
BIOLOGICAL
No Results Yet
40
Participants
Phase II Trial of Ubamatamab Alone or in Combination With Cemiplimab in MUC16-Expressing SMARCB1-Deficient Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-10-09
Completion:
2028-07-31
Conditions
SMARCB1-Deficient Malignancies
Interventions
DRUG
No Results Yet
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