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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06029517 | ACTIVE_NOT_RECRUITING | NA
48 Participants

A Sugar-Sweetened Beverage Reduction Intervention for Native American Men

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-07-20
Completion: 2025-09-15
Conditions
Cardiovascular Disorder Coronary Artery Disease Diabetes Mellitus Obesity-Related Malignant Neoplasm
Interventions
OTHER PROCEDURE
No Results Yet
NCT06022081 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-09-27
Completion: 2024-07-23
Conditions
Pneumothorax
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06022029 | RECRUITING | PHASE1
168 Participants

A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-10-13
Completion: 2026-04-30
Conditions
Triple Negative Breast Cancer Diffuse Large B Cell Lymphoma Follicular Lymphoma Lymphoma, Non-Hodgkin Mantle Cell Lymphoma Bladder Cancer Uveal Melanoma, Recurrent Cervix Cancer Carcinoma in Situ Head and Neck Squamous Cell Carcinoma Skin Cancer Metastatic Cancer Tumor, Solid Tumor Recurrence
Interventions
DRUG
No Results Yet
NCT06014086 | ACTIVE_NOT_RECRUITING | PHASE1
30 Participants

Intratumoral PH-762 for Cutaneous Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-07
Completion: 2026-01-31
Conditions
Malignant Melanoma of Skin Squamous Cell Carcinoma of the Skin Merkel Cell Carcinoma of Skin
Interventions
DRUG
No Results Yet
NCT06009276 | RECRUITING
70 Participants

Associations Between the Microbiome, Skeletal Muscle Perfusion, and Fitness Status

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-30
Completion: 2026-12-31
Conditions
Heart Failure, Diastolic Peripheral Arterial Disease Overweight and Obesity Heart Failure, Systolic
No Results Yet
NCT05996185 | RECRUITING | PHASE2
22 Participants

Study of Mogamulizumab With DA-EPOCH or CHOEP in Patients With Aggressive T-cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-10-09
Completion: 2026-11-30
Conditions
T Cell Lymphoma T-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT05977322 | TERMINATED | PHASE1
24 Participants

A Phase I Study of [177Lu]Lu-FF58 in Patients With Advanced Solid Tumors.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-10-06
Completion: 2024-12-13
Conditions
Pancreatic Ductal Adenocarcinoma Gastroesophageal Adenocarcinoma Glioblastoma Multiforme
Interventions
DRUG
No Results Yet
NCT05961956 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
5 Participants

Study With NVDX3 for Treatment of Low Grade Degenerative Lumbar Spondylolisthesis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-10-12
Completion: 2026-04-18
Conditions
Degenerative Lumbar Spondylolisthesis
Interventions
DRUG
No Results Yet
NCT05959304 | ACTIVE_NOT_RECRUITING | PHASE4
63 Participants

Post Marketing Study to Evaluate the Safety and Effectiveness of Brolucizumab in Patients With Diabetic Macular Edema.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-12-11
Completion: 2026-02-28
Conditions
Diabetic Macular Edema
Interventions
DRUG
No Results Yet
NCT05958667 | NOT_YET_RECRUITING | NA
1200 Participants

Quitxt Mobile Text Messaging Cessation Research Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2028-08-31
Conditions
Smoking Cessation
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT05947851 | RECRUITING | PHASE3
735 Participants

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-08
Completion: 2032-06-01
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Chronic Lymphocytic Small-Cell Lymphoma Lymphoma, Small Lymphocytic CLL SLL
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05938153 | COMPLETED
41 Participants

Evaluation of Metabolic Syndrome, Frailty, Locomotive Syndrome, Balance and Physical Fitness in Elderly Individuals

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-01
Completion: 2024-11-01
Conditions
Geriatrics Fragility Locomotor Physical Fitness Balance
Interventions
OTHER
No Results Yet
NCT05937373 | TERMINATED | NA
22 Participants

Perioperative Continuous Glucose Monitoring

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-04
Completion: 2024-05-21
Conditions
Diabetes Mellitus
Interventions
DEVICE OTHER
Results Available
NCT05934773 | TERMINATED | NA
5 Participants

Post-Brain Injury Walking and Balance Recovery Program

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2022-08-18
Completion: 2025-04-04
Conditions
Acquired Brain Injury Stroke Traumatic Brain Injury
Interventions
DEVICE
No Results Yet
NCT05934136 | COMPLETED | NA
60 Participants

Brain Health Program for Older Adults With Subjective Cognitive Decline

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-16
Completion: 2025-11-07
Conditions
Memory Loss (Excluding Dementia) Healthy Lifestyle Risk Reduction Behavior
Interventions
BEHAVIORAL
No Results Yet
NCT05932914 | NOT_YET_RECRUITING
8 Participants

Liver Biopsy Following Gene Therapy For Hemophilia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2026-01-31
Completion: 2030-01-31
Conditions
Hemophilia A Hemophilia B
Interventions
PROCEDURE
No Results Yet
NCT05929222 | RECRUITING | PHASE3
190 Participants

Comparison Between Local Radiotherapy Alone or Combined With Obinutuzumab in Early Stage Follicular Lymphoma: the GAZEBO Trial From the Fondazione Italiana Linfomi

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-12-14
Completion: 2031-04-30
Conditions
Follicular Lymphoma
Interventions
RADIATION OTHER
No Results Yet
NCT05926297 | COMPLETED | NA
92 Participants

Treatment of Peri-implant Mucositis by Sodium Hypochlorite Gel and Cross-linked Hyaluronic Acid Gel

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-06
Completion: 2025-07-01
Conditions
Peri-implant Mucositis Mucositis Oral
Interventions
PROCEDURE
No Results Yet
NCT05910528 | ACTIVE_NOT_RECRUITING | PHASE2
21 Participants

Afimkibart (RO7790121) for the Treatment of Moderate to Severe Active Crohn's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-24
Completion: 2030-12-31
Conditions
Crohns Disease
Interventions
DRUG
No Results Yet
NCT05905250 | COMPLETED | NA
155 Participants

mHealth for Young Adult Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-03-15
Completion: 2025-02-28
Conditions
Survivorship Cancer Psychological Well-Being
Interventions
BEHAVIORAL
Results Available
NCT05901649 | ACTIVE_NOT_RECRUITING
503 Participants

A Study for the Participants With Metastatic Hormone Sensitive Prostate Cancer (mHSPC) Treated With Androgen Deprivation Therapy (ADT) Plus Apalutamide or Enzalutamide

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-05
Completion: 2026-06-05
Conditions
Metastatic Hormone-sensitive Prostate Cancer
Interventions
DRUG
No Results Yet
NCT05887908 | COMPLETED | PHASE3
614 Participants

Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-05-23
Completion: 2024-11-22
Conditions
Complicated Urinary Tract Infection Acute Pyelonephritis cUTI AP
Interventions
DRUG
Results Available
NCT05887401 | COMPLETED | NA
72 Participants

Physical Activity and Healthy Eating Among Young Adult Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-10-02
Completion: 2024-09-30
Conditions
Physical Activity Neoplasms Cancer
Interventions
BEHAVIORAL
Results Available
NCT05887349 | COMPLETED | NA
62 Participants

Investigation of the Efficacy of Rocabado Exercises in Individuals With Chronic Neck Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-01
Completion: 2023-10-09
Conditions
Neck Pain
Interventions
OTHER
No Results Yet
NCT05864872 | COMPLETED | NA
140 Participants

the Best Approach for Blocking Intercostobrachial and Medial Brachial Cutaneous Nerves in the Upper Arm Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-05-01
Completion: 2024-06-30
Conditions
Pain
Interventions
PROCEDURE
No Results Yet
NCT05843253 | RECRUITING | PHASE2
120 Participants

Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-08-22
Completion: 2029-08-31
Conditions
Diffuse Intrinsic Pontine Glioma High Grade Glioma Anaplastic Astrocytoma Glioblastoma Glioblastoma Multiforme Diffuse Midline Glioma, H3 K27M-Mutant Metastatic Brain Tumor WHO Grade III Glioma WHO Grade IV Glioma Diffuse Hemispheric Glioma, H3 G34-Mutant
Interventions
DRUG
No Results Yet
NCT05842122 | ACTIVE_NOT_RECRUITING | NA
5808 Participants

Pharmacy-based PrEP Delivery in Kenya

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-20
Completion: 2025-06-30
Conditions
Hiv
Interventions
BEHAVIORAL
No Results Yet
NCT05841030 | ACTIVE_NOT_RECRUITING
545 Participants

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-04-28
Completion: 2026-03-13
Conditions
Depressive Disorder, Major
Interventions
OTHER
No Results Yet
NCT05838664 | COMPLETED
2140403 Participants

A Study to Learn About the Effects of Medicines That Help in Thinning the Blood in People With Atrial Fibrillation (AF) Between 2016 and 2020 in France

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-07
Completion: 2024-09-30
Conditions
Atrial Fibrillation
Interventions
DRUG
Results Available
NCT05838521 | RECRUITING | PHASE2
20 Participants

A Study of Sacituzumab Govitecan (IMMU-132) in Patients With Recurrent or Persistent Cervical Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-02
Completion: 2026-06-01
Conditions
Cervical Cancer
Interventions
DRUG
No Results Yet
NCT05836649 | COMPLETED | NA
265 Participants

Impact of Passive VR Versus Active VR on Heat Pain Thresholds and Pressure Pain Thresholds

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-08-04
Completion: 2024-01-03
Conditions
Pain Anxiety
Interventions
BEHAVIORAL
No Results Yet
NCT05830721 | RECRUITING | NA
6 Participants

Continuous Compartment Pressure Monitoring for Compartment Syndrome in VA-ECMO Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2024-01-02
Completion: 2026-12-31
Conditions
Compartment Syndrome of Leg Extracorporeal Membrane Oxygenation Complication Limb Ischemia Limb Ischemia, Critical
Interventions
DEVICE OTHER
No Results Yet
NCT05825716 | COMPLETED
3317 Participants

Ifaa Effectiveness Evaluation on Food Security and Nutrition

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-05-21
Completion: 2025-07-05
Conditions
Nutritional Wasting Nutritional Stunting
Interventions
OTHER BEHAVIORAL
No Results Yet
NCT05825482 | RECRUITING | NA
204 Participants

Breast Margin Study: Routine Cavity Shave Margins Vs. Selective Margins Using Savi Scout®

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-07-17
Completion: 2026-03-31
Conditions
Breast Cancer
Interventions
PROCEDURE
No Results Yet
NCT05825157 | RECRUITING | NA
60 Participants

Evaluation of Combination Therapy for Upper Extremity Lymphedema

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-11-17
Completion: 2027-01-01
Conditions
Lymphedema Arm
Interventions
DEVICE
No Results Yet
NCT05824182 | COMPLETED | NA
167 Participants

The FACE Self-help App for Fostering Resilience

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-05-31
Completion: 2025-01-23
Conditions
Adverse Childhood Experiences
Interventions
DEVICE
No Results Yet
NCT05819021 | ACTIVE_NOT_RECRUITING
1000 Participants

Open Label Optimization Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-04-06
Completion: 2026-10-15
Conditions
Major Depressive Disorder
Interventions
DEVICE
No Results Yet
NCT05817942 | ACTIVE_NOT_RECRUITING
509 Participants

Prospective Observational Study of Effectiveness and Safety of Filgotinib in Participants With Ulcerative Colitis (UC)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-06-12
Completion: 2027-12-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
NCT05817110 | ACTIVE_NOT_RECRUITING
712 Participants

Validating Artificial Intelligence Effectiveness Defined Lung Nodule Malignancy Score in Patients With Pulmonary Nodule.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-24
Start Date: 2023-04-20
Completion: 2026-12-06
Conditions
Lung Malignancy
Interventions
OTHER
No Results Yet
NCT05803421 | ACTIVE_NOT_RECRUITING | PHASE3
2749 Participants

A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

Study Type: INTERVENTIONAL
Last Updated: 2025-12-24
Start Date: 2023-04-03
Completion: 2026-03-31
Conditions
Type 2 Diabetes Obesity Overweight or Obesity Overweight Cardiovascular Diseases Chronic Kidney Disease
Interventions
DRUG
No Results Yet
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