Prospective Observational Study of Effectiveness and Safety of Filgotinib in Participants With Ulcerative Colitis (UC)
NCT ID: NCT05817942
Last Updated: 2025-12-24
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
ACTIVE_NOT_RECRUITING
509 participants
OBSERVATIONAL
2023-06-12
2027-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Arm A: Filgotinib
Participants diagnosed with moderately or severely active UC taking filgotinib according to local treatment guidelines or routine clinical practice and product information.
Filgotinib
Jyseleca
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Filgotinib
Jyseleca
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
Exclusion Criteria
2. Participant is diagnosed with Crohn's disease.
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Alfasigma S.p.A.
INDUSTRY
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Alfasigma Study Director
Role: STUDY_DIRECTOR
Alfasigma S.p.A.
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
LKH - Universitätsklinikum Graz
Graz, , Austria
Klinikum Klagenfurt am Wörthersee
Klagenfurt, , Austria
KH der Barmherzigen Brüder St.Veit an der Glan
Sankt Veit an der Glan, , Austria
AKH - Medizinische Universität Wien
Vienna, , Austria
Imeldaziekenhuis
Bonheiden, , Belgium
CHU Saint-Pierre
Brussels, , Belgium
Cliniques Universitaires de Bruxelles Hopital Erasme
Brussels, , Belgium
UZA
Edegem, , Belgium
AZ Maria Middelares
Ghent, , Belgium
AZ Sint-Lucas
Ghent, , Belgium
Universitair Ziekenhuis Gent
Ghent, , Belgium
Sint-Franciscus ziekenhuis
Heusden-Zolder, , Belgium
UZ Leuven
Leuven, , Belgium
CHU de Liège
Liège, , Belgium
Clinique CHC MontLégia
Liège, , Belgium
AZ Damiaan
Ostend, , Belgium
CHU Amiens - Hopital Sud
Amiens, , France
Hôpital Jean Minjoz
Besançon, , France
Clinique Abroise Paré
Clichy, , France
CHU de Grenoble - Hôpital Nord
Grenoble, , France
CHU Lille - Hôpital Claude Huriez
Lille, , France
CHU Montpellier- Hôpital Saint Eloi
Montpellier, , France
CHRU de Nancy
Nancy, , France
CHU Nantes - Hôtel Dieu
Nantes, , France
Hôpital Saint-Louis
Paris, , France
CHU Bordeaux - Hôpital Haut-Lévêque
Pessac, , France
Centre Hospitalier Lyon Sud
Pierre-Bénite, , France
CHU Saint Etienne - Hôpital Nord
Saint-Etienne, , France
Hôpital Rangueil
Toulouse, , France
Synesis GmbH
Grünwald, Bavaria, Germany
Klinikum St. Marien Amberg
Amberg, , Germany
Medizinisches Versorgungszentrum Dachau
Dachau, , Germany
Fachinternistische Schwerpunktpraxis
Hamburg, , Germany
Praxis fur Gastroenterologie
Heidelberg, , Germany
Universitaetsklinikum Schleswig-Holstein
Kiel, , Germany
Universitätsklinikum Leipzig AöR
Leipzig, , Germany
Gastro Campus Research GbR
Münster, , Germany
Magen-Darm-Zentrum Remscheid
Remscheid, , Germany
Universitätsklinikum Tübingen
Tübingen, , Germany
Cork University Hospital
Cork, , Ireland
St Vincent's University Hospital
Dublin, , Ireland
Beaumont Hospital
Dublin, , Ireland
Azienda Ospedaliera Saverio De Bellis - Castellana Grotte
Bari, Italia, Italy
IRCCS Ospedale San Raffaele ,Via Olgettina 60
Milan, Italia, Italy
Azienda Ospedaliero Universitaria Pisana - Cisanello
Pisa, Italia, Italy
Fondazione IRCCS CA' Granda Ospedale Maggiore Policlinico
Milan, , Italy
ASST Fatebenefratelli Sacco
Milan, , Italy
IRCCS Ospedale Sacro Cuore Don Calabria
Negrar, , Italy
Azienda Ospedaliera Ospedali Riuniti Villa Sofia - Cervello
Palermo, , Italy
IRCCS Istituto Clinico Humanitas
Rozzano, , Italy
Ospedale Mauriziano Umberto I
Torino, , Italy
Onze Lieve Vrouwe Gasthuis
Amsterdam, , Netherlands
Amsterdam UMC (AMC)
Amsterdam, , Netherlands
Zuyderland Medisch Centrum - Sittard-Geleen
Geleen, , Netherlands
Radboud UMC
Nijmegen, , Netherlands
Erasmus MC
Rotterdam, , Netherlands
Franciscus Gasthuis
Rotterdam, , Netherlands
ETZ Elisabeth
Tilburg, , Netherlands
UMC Utrecht
Utrecht, , Netherlands
Nordlandsykehuset
Bodø, , Norway
Akershus Universitetssykehus
Lørenskog, , Norway
Oslo University Hospital
Oslo, , Norway
Bærum Hospital , Gjettum
Oslo, , Norway
Universitetssykehuset Nord-Norge
Tromsø, , Norway
St. Olav's University Hospital
Trondheim, , Norway
Hospital de la Santa Creu i Sant Pau
Barcelona, Catalonia, Spain
Hospital Universitari Germans Trias i Pujol
Badalona, Spain, Spain
Hospital Clinic de Barcelona, C/ Villarroel, 170
Barcelona, Spain, Spain
Hospital Universitario de Gran Canaria Dr. Negrin
Las Palmas de Gran Canaria, Spain, Spain
Hospital Universitari Son Espases
Palma de Mallorca, Spain, Spain
Hospital Universitario de Santiago de Compostela
Santiago de Compostela, Spain, Spain
The Ulster Hospital
Belfast, , United Kingdom
Bury Care Organisation
Bury, , United Kingdom
Royal Devon University Healthcare NHS Foundation trust
Exeter, , United Kingdom
Glasgow Royal Infirmary
Glasgow, , United Kingdom
Queen Elizabeth University Hospital
Glasgow, , United Kingdom
St Mark's Hospital, Central Middlesex, Acton Lane
London, , United Kingdom
St George's Hospital
London, , United Kingdom
Norfolk and Norwich University Hospital
Norwich, , United Kingdom
John Radcliffe Hospital
Oxford, , United Kingdom
Southampton General Hospital
Southampton, , United Kingdom
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
105477
Identifier Type: OTHER
Identifier Source: secondary_id
GLPG0634-CL-425
Identifier Type: -
Identifier Source: org_study_id