Clinical Trials
Showing trials with last updates posted in 2025.
1837
Participants
Multilevel Interventions to Increase Adherence to Lung Cancer Screening
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-12-12
Completion:
2025-07-05
Conditions
Lung Cancer
Lung Cancer Screening
Interventions
OTHER
No Results Yet
68
Participants
Insulin and Abatacept in Recently-diagnosed Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-02-13
Completion:
2025-09-30
Conditions
Type 1 Diabetes
Diabetes Mellitus, Type 1
Interventions
DRUG
No Results Yet
20
Participants
Supramarginal Resection in Glioblastoma Guided by Artificial Intelligence
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-01
Completion:
2025-05-30
Conditions
Glioblastoma
Interventions
PROCEDURE
No Results Yet
416
Participants
TEZSPIRE (Tezepelumab) Asthma Japan Post-Marketing Study (PMS)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-04-04
Completion:
2029-11-16
Conditions
Bronchial Asthma (Only the Patients With Severe or Intractable Bronchial Asthma Which Could Not be Controlled With the Existing Therapy)
No Results Yet
18
Participants
vGRID SBRT: A Phase I Clinical Trial in Unresectable or Metastatic HCC
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-02-23
Completion:
2026-08-31
Conditions
Liver Cancer
Interventions
RADIATION
No Results Yet
36
Participants
Pioglitazone-Metformin Combination Treatment for High Risk Oral Preneoplasia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2025-01-01
Completion:
2026-07-28
Conditions
Oral Leukoplakia
Interventions
DRUG
No Results Yet
0
Participants
The Role of Perturbed Auditory Information for Self-motion in Gait
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-01-01
Completion:
2026-06-30
Conditions
Gait
Interventions
BEHAVIORAL
No Results Yet
170
Participants
A Phase 2 Study of the Ketogenic Diet vs Standard Anti-cancer Diet Guidance for Patients With Glioblastoma in Combination With Standard-of-care Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-27
Completion:
2028-09-30
Conditions
Glioblastoma Multiforme
Interventions
BEHAVIORAL
No Results Yet
160
Participants
GMMG-HD10 / DSMM-XX / 64007957MMY2003, MajesTEC-5
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-12-01
Completion:
2028-09-15
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
12
Participants
Safety and Tolerability of VGR-R01 for Patients With Bietti Crystalline Dystrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-03-27
Completion:
2024-09-13
Conditions
Bietti Crystalline Dystrophy
Interventions
GENETIC
No Results Yet
323
Participants
Developing and Evaluating Culturally Relevant Interventions to Improve Breast Cancer Screening
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-06
Completion:
2025-09-26
Conditions
Breast Cancer
Interventions
BEHAVIORAL
No Results Yet
220
Participants
Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-08
Completion:
2029-08-01
Conditions
Stage III Ovarian Cancer
Stage IV Ovarian Cancer
Stage III Primary Peritoneal Cancer
Stage IV Primary Peritoneal Cancer
Stage III Fallopian Tube Cancer
Stage IV Fallopian Tube Cancer
Interventions
DRUG
OTHER
No Results Yet
148
Participants
Hemithoracic Irradiation With Proton Therapy in Malignant Pleural Mesothelioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-28
Completion:
2029-03-31
Conditions
Malignant Pleural Mesothelioma
Interventions
RADIATION
No Results Yet
180
Participants
A Study of JNJ-79635322 in Participants With Relapsed or Refractory Multiple Myeloma or Previously Treated Amyloid Light-chain (AL) Amyloidosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-22
Completion:
2027-04-19
Conditions
Relapsed or Refractory Multiple Myeloma
Previously Treated Amyloid Light-chain (AL) Amyloidosis
Interventions
DRUG
No Results Yet
91
Participants
An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-03-07
Completion:
2026-12-31
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
No Results Yet
502
Participants
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-03-07
Completion:
2030-03-12
Conditions
Aortic Stenosis
Interventions
DRUG
No Results Yet
75
Participants
Dynamic Neural Systems Underlying Social-emotional Functions in Older Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-10-13
Completion:
2025-12-28
Conditions
Loneliness
Older Adults
fMRI
Emotions
EEG
Digital Intervention
Meditation
Interventions
BEHAVIORAL
OTHER
No Results Yet
40
Participants
Effect of Nordic Walking on Gait-asymmetry Patterns in Children With Hemiparesis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-01-01
Completion:
2024-01-30
Conditions
Cerebral Palsy
Interventions
OTHER
No Results Yet
30
Participants
Prehabilitation Feasibility Among Older Adults Undergoing Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-07-10
Completion:
2026-12-31
Conditions
Multiple Myeloma
Interventions
OTHER
BEHAVIORAL
No Results Yet
37
Participants
Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Osimertinib (TAGRISSO) (ROSY-T)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-05-08
Completion:
2027-02-22
Conditions
Cancer
Interventions
DRUG
No Results Yet
915
Participants
Precision Prevention Strategy to Increase Uptake and Engagement in Lung Cancer Screening and Smoking Cessation Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-01-01
Completion:
2027-08-31
Conditions
Smoking
Smoking Cessation
Tobacco Use Cessation
Interventions
BEHAVIORAL
No Results Yet
56
Participants
A Study to Look at Safety and Tolerability of NNC0582-0001, How it is Transported Throughout the Body and How it Works in Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-15
Completion:
2025-10-16
Conditions
Healthy Volunteers
Interventions
DRUG
No Results Yet
10
Participants
Pilot Study of MC in Paediatric Palliative Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-19
Completion:
2026-10-31
Conditions
Palliative Care
Interventions
DRUG
No Results Yet
614
Participants
Study of Pembrolizumab (MK-3475) Monotherapy Versus Sacituzumab Govitecan in Combination With Pembrolizumab for Participants With Metastatic Non-small Cell Lung Cancer (NSCLC) With Programmed Cell Death Ligand 1 (PD-L1) Tumor Proportion Score (TPS) ≥50% (MK-3475-D46)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-02-06
Completion:
2027-01-12
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
BIOLOGICAL
No Results Yet
348
Participants
Early Administration of Tirofiban in Patients Treated With Tenecteplase for Acute Ischemic Stroke
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-04-24
Completion:
2025-12-31
Conditions
Acute Ischemic Stroke
Interventions
DRUG
No Results Yet
60
Participants
A Single-arm, Dose-escalation Trial of Long-acting Recombinant Human IL-7 (NT-I7, Efineptakin Alfa) for Idiopathic CD4 Lymphopenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-11-06
Completion:
2026-11-01
Conditions
Idiopathic CD4 Lymphopenia
Interventions
DRUG
No Results Yet
72
Participants
Experience With Topical Acne Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-02-15
Completion:
2025-06-19
Conditions
Acne
Interventions
DRUG
No Results Yet
48
Participants
A Substudy of Investigational Agents in Programmed Cell Death-1/Ligand 1 (PD-1/L1) Refractory Locally Advanced or Metastatic Urothelial Carcinoma (mUC) (MK-3475-04A)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-16
Completion:
2028-06-20
Conditions
Urothelial Carcinoma
Interventions
BIOLOGICAL
No Results Yet
40
Participants
A First in Human Study of IBC-Ab002 in Persons With Early Alzheimer's Disease (AD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-02-23
Completion:
2025-12-16
Conditions
Alzheimer's Disease
Interventions
BIOLOGICAL
OTHER
No Results Yet
80
Participants
Transcranial Pulse Stimulation for Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-06-01
Completion:
2025-10-30
Conditions
Major Depression
Interventions
DEVICE
No Results Yet
224
Participants
Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-11-29
Completion:
2027-05-25
Conditions
Bladder Carcinoma
Genitourinary System Neoplasm
Kidney Carcinoma
Prostate Carcinoma
Interventions
OTHER
DEVICE
BEHAVIORAL
No Results Yet
304
Participants
Study of Pregnancy And Neonatal Health (SPAN)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-01-20
Completion:
2024-12-16
Conditions
Gestational Diabetes Mellitus
Interventions
PROCEDURE
No Results Yet
1500
Participants
A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-10-10
Completion:
2028-05-31
Conditions
Alzheimer Disease
Dementia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Tauopathies
Neurodegenerative Diseases
Neurocognitive Disorders
Mental Disorders
Interventions
DRUG
No Results Yet
31
Participants
FitMi AD Home Therapy for Individuals With MCI or Mild Dementia Due to Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2023-09-08
Completion:
2025-03-12
Conditions
Cognitive Dysfunction
Dementia, Mild
Interventions
DEVICE
OTHER
No Results Yet
110
Participants
Neuropsychological Care for Maintaining Quality of Life After Radiation Therapy in Patients With Brain Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-08-30
Completion:
2026-06-28
Conditions
Metastatic Malignant Neoplasm in the Brain
Metastatic Malignant Solid Neoplasm
Interventions
OTHER
BEHAVIORAL
No Results Yet
226
Participants
Muscle O2 Saturation and Hemoglobin Levels During Rehabilitation From Arthroscopic Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-08-08
Completion:
2026-12-31
Conditions
ACL Injury
Hip Injuries
Interventions
PROCEDURE
DEVICE
No Results Yet
20
Participants
Innovative Multimodal and Attention Training to Improve Emotion Communication in Veterans With TBI and PTSD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-12-01
Completion:
2026-05-30
Conditions
Brain Injury
Post Traumatic Stress Disorder
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Observational Lung Trial to Collect Tissue to Train and Validate a Live Tumor Diagnostic Platform
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2023-01-31
Completion:
2026-12-31
Conditions
NSCLC (Non-small Cell Lung Cancer)
Metastatic NSCLC - Non-Small Cell Lung Cancer
Interventions
PROCEDURE
No Results Yet
500
Participants
ACCESS 2: AI for pediatriC diabetiC Eye examS Study 2
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-07-11
Completion:
2026-03-30
Conditions
Type 1 Diabetes
Type 2 Diabetes
Cystic Fibrosis-related Diabetes
Interventions
DIAGNOSTIC_TEST
No Results Yet
223
Participants
A Study of Zilovertamab Vedotin (MK-2140) as Monotherapy and in Combination in Participants With Aggressive and Indolent B-cell Malignancies (MK-2140-006)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-07-21
Completion:
2029-05-17
Conditions
Chronic Lymphocytic Leukemia
Mantle Cell Lymphoma
Follicular Lymphoma
Richter Transformation Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
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