Clinical Trials
Showing trials with last updates posted in 2025.
68
Participants
Genome-Wide Assocation Study in Patients With Brain Injury Associated Fatigue and Altered Cognition (BIAFAC)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-21
Completion:
2024-01-18
Conditions
Traumatic Brain Injury
No Results Yet
985
Participants
A Study to Evaluate the Efficacy and Safety of Fenebrutinib Compared With Ocrelizumab in Adult Participants With Primary Progressive Multiple Sclerosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-26
Completion:
2025-09-17
Conditions
Multiple Sclerosis, Primary Progressive
Interventions
DRUG
No Results Yet
100
Participants
Study on a High-Dose Quadrivalent Influenza Vaccine Compared With Standard-Dose Quadrivalent Influenza Vaccine in Children 6 Months Through 35 Months of Age
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-09-15
Completion:
2021-06-02
Conditions
Influenza
Interventions
BIOLOGICAL
59
Participants
Safety, Tolerability and Pharmacokinetics of Multiple Ascending Doses of NIO752 in Progressive Supranuclear Palsy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-02-16
Completion:
2024-10-17
Conditions
Progressive Supranuclear Palsy (PSP)
Interventions
DRUG
No Results Yet
5176
Participants
Framing Clinical Trial Enrollment for Patients With Peripheral Artery Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-05
Completion:
2023-05-31
Conditions
Peripheral Artery Disease
Interventions
BEHAVIORAL
1000
Participants
Interest of Circulating Tumor DNA in Digestive and Gynecologic/Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-08
Completion:
2032-03-31
Conditions
Breast Cancer
Digestive Cancer
Gynecologic Cancer
Circulating Tumor DNA
Exosomes
Interventions
DIAGNOSTIC_TEST
No Results Yet
26
Participants
Surgical Treatment of Post-surgical Mastectomy Pain Utilizing the Regenerative Peripheral Nerve Interface
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-12
Completion:
2023-06-30
Conditions
Post-Mastectomy Chronic Pain Syndrome
Interventions
PROCEDURE
611
Participants
A Combination of Acalabrutinib With R-CHOP in Subjects With Previously Untreated Non-GCB DLBCL (ACE-LY-312)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-10-08
Completion:
2027-02-01
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG
No Results Yet
230
Participants
Immune Response to Anti-HER2 Therapies in Patients With HER2-Positive Stage I-IV Breast Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2020-07-31
Completion:
2028-07-27
Conditions
Breast Adenocarcinoma
HER2-Positive Breast Carcinoma
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Interventions
PROCEDURE
No Results Yet
25
Participants
Phase II Panitumumab-IRDye800 in Head & Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-04-02
Completion:
2030-12-31
Conditions
Head and Neck Cancer
Interventions
DRUG
No Results Yet
116
Participants
Baroreflex Sensitivity in Patients Undergoing Ablation of Atrial Fibrillation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-06-22
Completion:
2025-11-13
Conditions
Paroxysmal Atrial Fibrillation
Interventions
PROCEDURE
No Results Yet
1100
Participants
Natural History of Autosomal Dominant Hearing Loss
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-02-09
Completion:
2029-08-21
Conditions
Hearing Loss
No Results Yet
74
Participants
Academic-Community EPINET (AC-EPINET)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2022-03-16
Completion:
2025-07-29
Conditions
Schizophrenia
Schizoaffective Disorder
Schizophreniform Disorders
Major Depression With Psychotic Features
Bipolar Disorder With Psychotic Features
Interventions
OTHER
No Results Yet
45
Participants
Analgesic and Subjective Effects of Terpenes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-12-15
Completion:
2025-11-12
Conditions
Pain
Abuse, Drug
Interventions
DRUG
No Results Yet
82
Participants
Rapid Analysis and Response Evaluation of Combination Anti-Neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 1 Nilotinib and Paclitaxel
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-08-24
Completion:
2026-04-02
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
800
Participants
Prospective Evaluation of High Resolution Dual Energy Computed Tomographic Imaging, Noninvasive (Liquid) Biopsies, and Minimally Invasive Surgical Surveillance for Early Detection of Mesotheliomas in Patients With BAP1 Tumor Predisposition Syndrome
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2021-03-30
Completion:
2038-06-30
Conditions
Familial Cancer
BRCA1-Associated Protein-1 (BAP1) Mutations
Tumor Predisposition Syndrome (TPDS)
Mesothelioma
No Results Yet
100
Participants
Study to Investigate Efficacy of a Novel Probiotic on the Bacteriome and Mycobiome of Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2026-02-28
Completion:
2026-12-31
Conditions
Breast Cancer
Interventions
BIOLOGICAL
OTHER
No Results Yet
20
Participants
Autologous Transplantation of Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelium for Geographic Atrophy Associated With Age-Related Macular Degeneration
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-09-23
Completion:
2029-05-31
Conditions
Dry Age-Related Macular Degeneration
Geographic Atrophy
Interventions
DRUG
No Results Yet
1000
Participants
Total Joint Arthroplasty in a Pediatric Population
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-06-03
Completion:
2050-03-31
Conditions
Total Joint Arthroplasty
No Results Yet
122
Participants
A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-07-22
Completion:
2024-09-25
Conditions
BRAF V600 Colorectal Cancer
Interventions
DRUG
BIOLOGICAL
No Results Yet
600
Participants
Genome Environment Microbiome and Metabolome in Autism Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-01
Completion:
2025-12-31
Conditions
Autism Spectrum Disorder
No Results Yet
4000
Participants
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-02-12
Completion:
2029-01-31
Conditions
Infertility
in Vitro Fertilization (IVF)
ART
Interventions
OTHER
No Results Yet
0
Participants
Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-09-15
Completion:
2023-05-01
Conditions
Cirrhosis, Liver
Minimal Hepatic Encephalopathy
Small Intestinal Bacterial Overgrowth
Gastrointestinal Motility Disorder
Interventions
DRUG
No Results Yet
51
Participants
Venetoclax and Azacitidine for the Treatment of High-Risk Recurrent or Refractory Myelodysplastic Syndrome
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-10-01
Completion:
2027-12-31
Conditions
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Recurrent Myelodysplastic Syndrome
Refractory Myelodysplastic Syndrome
Therapy-Related Myelodysplastic Syndrome
Interventions
DRUG
No Results Yet
7
Participants
Study of Autologous Peripheral Blood Lymphocytes in the Treatment of Patients With CLL or SLL
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-02-19
Completion:
2024-11-11
Conditions
Chronic Lymphocytic Leukemia
Small Lymphocytic Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
30
Participants
Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2021-10-21
Completion:
2027-06-30
Conditions
Pancreatic Cancer
Pancreatic Neoplasms
Pancreatic Ductal Adenocarcinoma
Advanced Cancer
Interventions
DRUG
BIOLOGICAL
No Results Yet
400
Participants
The Effect of IoT-based Smart Exercises System in the Senior Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-07-15
Completion:
2027-08-31
Conditions
Elderly Exercise
Interventions
DEVICE
No Results Yet
56
Participants
A Study of WVT078 in Patients With Multiple Myeloma (MM)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-12-05
Completion:
2024-12-02
Conditions
Multiple Myeloma (MM)
Interventions
BIOLOGICAL
DRUG
No Results Yet
58
Participants
A Study of Baricitinib (LY3009104) in Participants From 1 Year to Less Than 18 Years Old With Systemic Juvenile Idiopathic Arthritis (sJIA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2020-02-12
Completion:
2026-04-30
Conditions
Systemic Juvenile Idiopathic Arthritis
Interventions
DRUG
No Results Yet
Intermediate Expanded Access Protocol CNMAu8.EAP03
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-24
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
701
Participants
A Study of Lazertinib as Monotherapy or in Combination With Amivantamab in Participants With Advanced Non-small Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-04
Completion:
2026-06-03
Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG
No Results Yet
10
Participants
Passport to Freedom (P2F): Adaptation and Implementation of a Wellness Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-10-28
Completion:
2021-10-23
Conditions
Trauma
Interventions
BEHAVIORAL
No Results Yet
32
Participants
OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-11-04
Completion:
2026-12-31
Conditions
Liver Metastases
Stereotactic Body Radiation Therapy
MRI-guided Treatment
Interventions
RADIATION
No Results Yet
28
Participants
Phase II Study to Evaluate Modified Folfirinox and Stereotactic Body Radiation Therapy in Non-metastatic Unresectable Pancreatic Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-24
Completion:
2026-08-31
Conditions
Pancreatic Cancer
Interventions
DRUG
RADIATION
No Results Yet
32
Participants
Neural Control of Kidney Blood Flow During Exercise in African American Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2024-09-30
Completion:
2026-04-30
Conditions
Healthy
Interventions
OTHER
No Results Yet
94
Participants
A Preoperative Cognitive Behavioural Therapy Program Based on Self-determination Theory for Bariatric Surgery Candidates
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2018-02-05
Completion:
2020-09-05
Conditions
Bariatric Surgery Candidate
Obesity
Interventions
BEHAVIORAL
No Results Yet
200
Participants
A Study to Test Efficacy and Safety of Rozanolixizumab in Adult Patients With Generalized Myasthenia Gravis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-06-03
Completion:
2021-08-31
Conditions
Generalized Myasthenia Gravis
Interventions
DRUG
OTHER
692
Participants
Patient-Centered Assessment of Symptoms and Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-24
Start Date:
2019-09-13
Completion:
2026-06-01
Conditions
Sjogrens
Fatigue
Cancer
CFS
ME/CFS
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
Lupus
Systemic Lupus Erthematosus
No Results Yet
30
Participants
C-Brace II Spinal Cord Injury
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-16
Completion:
2026-11-30
Conditions
Spinal Cord Injury
Interventions
DEVICE
No Results Yet
332
Participants
A Study to Evaluate the Efficacy and Safety of Bimekizumab in Subjects With Active Ankylosing Spondylitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-24
Start Date:
2019-04-25
Completion:
2021-09-03
Conditions
Ankylosing Spondylitis
Interventions
DRUG
OTHER
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