Clinical Trials Updated in 2025

NCT03576846 | COMPLETED | NA

131 Participants

Spinal Pain and Autonomic Responses to Chiropractic Care

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2019-01-04

Completion: 2020-05-02

Conditions

Neck Pain

Interventions

OTHER

Results Available

NCT03514017 | TERMINATED | PHASE2

5 Participants

Ibrutinib and PD-1 Blockade in High Risk Lymphocytic Leukemia

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2019-05-31

Completion: 2023-05-16

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

Results Available

NCT03506867 | ENROLLING_BY_INVITATION | NA

250 Participants

Healthy People Initiative (HPI)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2019-01-03

Completion: 2027-03-31

Conditions

Nicotine Dependence Substance Use Disorders

Interventions

BEHAVIORAL

No Results Yet

NCT03488628 | COMPLETED | NA

51 Participants

High-Flow Nasal Oxygen Therapy for Exacerbation of Chronic Pulmonary Obstructive Disease.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-06-27

Completion: 2025-10-03

Conditions

Pulmonary Disease, Chronic Obstructive

Interventions

OTHER

No Results Yet

NCT03486873 | RECRUITING | PHASE3

3500 Participants

Long-term Safety and Efficacy Extension Study for Participants With Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab (MK-3475) Study (MK-3475-587/KEYNOTE-587)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-08-21

Completion: 2043-08-04

Conditions

Solid Tumors Hematologic Malignancies

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT03473249 | ACTIVE_NOT_RECRUITING | PHASE4

120 Participants

Effectiveness of Contrast-Enhanced Ultrasound

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-05-09

Completion: 2026-12-31

Conditions

Abdominal Injuries Physical Abuse Accidental Fall Motor Vehicle Injury

Interventions

DRUG

No Results Yet

NCT03467867 | ACTIVE_NOT_RECRUITING | PHASE2

25 Participants

A Study of Venetoclax and Rituximab/Hyaluronidase Human in Relapsed/Refractory CLL

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-04-26

Completion: 2026-12-31

Conditions

Chronic Lymphocytic Leukemia

Interventions

DRUG

No Results Yet

NCT03412045 | COMPLETED | NA

8 Participants

Hyperbaric Oxygen Therapy in Sickle Cell Pain

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2022-09-01

Completion: 2025-06-05

Conditions

Vaso-occlusive Crisis Sickle Cell Anemia Crisis

Interventions

DEVICE

No Results Yet

NCT03406208 | COMPLETED | NA

228 Participants

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-10-01

Completion: 2022-02-28

Conditions

Neurofibromatoses Neurofibromatosis 1 Neurofibromatosis 2 Schwannomatosis

Interventions

BEHAVIORAL

No Results Yet

NCT03394066 | RECRUITING | NA

70 Participants

Mechanism of Non-invasive Magnetic Stimulation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-09-19

Completion: 2026-12-31

Conditions

Healthy Volunteers

Interventions

DEVICE

No Results Yet

NCT03362242 | COMPLETED | PHASE1

45 Participants

Study of ARO-AAT in Normal Adult Volunteers

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-03-12

Completion: 2018-10-23

Conditions

Alpha 1-Antitrypsin Deficiency

Interventions

DRUG OTHER

No Results Yet

NCT03351764 | COMPLETED | NA

83 Participants

Development of Non-Invasive Brain Stimulation Techniques

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-01-11

Completion: 2025-12-15

Conditions

Normal Physiology

Interventions

DEVICE

No Results Yet

NCT03348280 | ACTIVE_NOT_RECRUITING

40 Participants

Vitamin D and Immune Mechanisms of Hypertension in Type 2 Diabetics

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-09-01

Completion: 2026-12-31

Conditions

Diabetes Mellitus, Type 2 Hypertension Vitamin D Deficiency

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT03294863 | ACTIVE_NOT_RECRUITING | NA

12 Participants

Effectiveness of Embrace Scar Therapy Device After Cutaneous Wound Closure

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-03-15

Completion: 2021-12-01

Conditions

Linear Cutaneous Wound

Interventions

DEVICE OTHER

No Results Yet

NCT03269721 | COMPLETED

170 Participants

COPD-Related Physiology and the Brain

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-05-01

Completion: 2025-04-30

Conditions

Pulmonary Disease, Chronic Obstructive (COPD) Cognitive Impairment

Interventions

BEHAVIORAL PROCEDURE DIAGNOSTIC_TEST BIOLOGICAL

No Results Yet

NCT03261089 | RECRUITING

600 Participants

Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-08-02

Completion: 2027-08-31

Conditions

Cardiac Arrest

No Results Yet

NCT03111745 | COMPLETED

730 Participants

Retrospective Study of Viral Reactivation Across All Bone Marrow Transplant Protocols Since 2010

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-04-13

Completion: 2018-12-29

Conditions

Viral Infections

No Results Yet

NCT03091452 | RECRUITING

2000 Participants

CArdioSurgEry Atrial Fibrillation Register

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-01-31

Completion: 2028-12-31

Conditions

Atrial Fibrillation

No Results Yet

NCT03076554 | ACTIVE_NOT_RECRUITING | PHASE2

56 Participants

A Pilot Study to Investigate the Safety and Clinical Activity of Avelumab (MSB0010718C) in Thymoma and Thymic Carcinoma After Progression on Platinum-Based Chemotherapy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-04-19

Completion: 2026-06-30

Conditions

Thymoma Thymic Carcinoma

Interventions

DRUG

No Results Yet

NCT03049475 | COMPLETED

99 Participants

Pathophysiology of Acute Pain in Patients With Sickle Cell Disease

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2017-03-13

Completion: 2019-12-09

Conditions

Sickle Cell Disease

No Results Yet

NCT03017573 | RECRUITING | NA

1050 Participants

Prospective Biobanking Study in Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself, Its Microenvironment and Immune Response (SCANDARE)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-01-06

Completion: 2029-08-06

Conditions

Ovarian Cancer Triple-Negative Breast Cancer Head and Neck Cancer Cervical Cancer Sarcoma

Interventions

PROCEDURE

No Results Yet

NCT03008291 | RECRUITING

80 Participants

His Bundle Pacing in Bradycardia and Heart Failure

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2016-10-31

Completion: 2026-12-31

Conditions

Bradycardia Heart Failure

Interventions

PROCEDURE

No Results Yet

NCT03003962 | ACTIVE_NOT_RECRUITING | PHASE3

669 Participants

Study of Durvalumab Alone or Chemotherapy for Patients With Advanced Non Small-Cell Lung Cancer (PEARL)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-01-02

Completion: 2022-10-27

Conditions

Non Small Cell Lung Carcinoma NSCLC

Interventions

DRUG

Results Available

NCT02991469 | RECRUITING | PHASE2

51 Participants

A Repeated Dose-finding Study of Sarilumab in Children and Adolescents With Systemic Juvenile Idiopathic Arthritis (SKYPS)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-08-09

Completion: 2026-04-01

Conditions

Juvenile Idiopathic Arthritis

Interventions

DRUG

No Results Yet

NCT02988128 | RECRUITING

4000 Participants

Neurovascular Product Surveillance Registry

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2016-12-31

Completion: 2032-08-31

Conditions

Intracranial Aneurysm Stroke, Ischemic

Interventions

DEVICE

No Results Yet

NCT02975180 | COMPLETED | NA

11 Participants

FES in Young Children With Perinatal Stroke

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-01-01

Completion: 2020-12-10

Conditions

Cerebral Palsy

Interventions

DEVICE BEHAVIORAL

No Results Yet

NCT02973633 | RECRUITING | EARLY_PHASE1

160 Participants

Diffusion MRI in Heart Failure

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-06-30

Completion: 2027-12-31

Conditions

Myocardial Infarction Heart Failure Left Ventricular Hypertrophy

Interventions

DEVICE DRUG

No Results Yet

NCT02966756 | RECRUITING | PHASE2

110 Participants

A Study of Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-10-12

Completion: 2029-05-31

Conditions

Chronic Lymphocytic Leukemia (CLL) Small Lymphocytic Lymphoma (SLL)

Interventions

DRUG

No Results Yet

NCT02911714 | TERMINATED | PHASE1

20 Participants

Contrast-Enhanced Ultrasound for Kidney Transplant

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2018-02-21

Completion: 2022-06-30

Conditions

Kidney Transplantation

Interventions

DRUG

No Results Yet

NCT02830724 | RECRUITING | PHASE1/PHASE2

124 Participants

Administering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing Cancers

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-04-06

Completion: 2027-01-01

Conditions

Pancreatic Cancer Renal Cell Cancer Breast Cancer Melanoma Ovarian Cancer

Interventions

DRUG BIOLOGICAL

No Results Yet

NCT02819037 | COMPLETED | NA

51 Participants

Small Intestinal Bacterial Overgrowth Obese

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2016-05-27

Completion: 2022-10-07

Conditions

Gastric Bypass Blind Loop Syndrome Bacterial Overgrowth Syndrome Chromatography, Gas

Interventions

PROCEDURE

No Results Yet

NCT02815891 | RECRUITING

15000 Participants

A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2016-07-31

Completion: 2036-07-31

Conditions

Nonalcoholic Fatty Liver Nonalcoholic Steatohepatitis

No Results Yet

NCT02782546 | ACTIVE_NOT_RECRUITING | PHASE2

60 Participants

Cytokine Induced Memory-like NK Cell Adoptive Therapy After Haploidentical Donor Hematopoietic Cell Transplantation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2017-01-30

Completion: 2025-10-27

Conditions

Acute Myeloid Leukemia

Interventions

PROCEDURE DRUG

No Results Yet

NCT02771236 | RECRUITING

5000 Participants

Clinical and Molecular Studies in Families With Inherited Eye Disease

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2016-10-04

Completion: 2032-01-01

Conditions

Inherited Eye Disease

No Results Yet

NCT02734069 | RECRUITING

132 Participants

Impact of Fat-free Mass in the Carboplatin Calculated Dose and Chemotherapeutic Toxicity in Patients With Advanced NSCLC

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2016-02-29

Completion: 2026-12-31

Conditions

Lung Cancer Sarcopenia Toxicity

Interventions

DRUG

No Results Yet

NCT02650401 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

69 Participants

Study Of Entrectinib (Rxdx-101) in Children and Adolescents With Locally Advanced Or Metastatic Solid Or Primary CNS Tumors And/Or Who Have No Satisfactory Treatment Options

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2016-05-03

Completion: 2026-06-30

Conditions

Solid Tumors CNS Tumors

Interventions

DRUG

No Results Yet

NCT02629120 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

45 Participants

High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-24

Start Date: 2015-12-17

Completion: 2027-12-30

Conditions

Chronic Granulomatous Disease Transplant

Interventions

DRUG RADIATION BIOLOGICAL

No Results Yet

NCT02450851 | RECRUITING

20000 Participants

Clinical and Genetic Evaluation of Individuals With Undiagnosed Disorders Through the Undiagnosed Diseases Network

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2015-09-16

Completion: 2028-12-31

Conditions

Genetic Disease

No Results Yet

NCT02417714 | RECRUITING

215 Participants

Prospective Evaluation of Next Generation CT Reconstruction (NextGenIR)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2014-09-08

Completion: 2026-06-30

Conditions

Healthy Subjects

No Results Yet

NCT02405208 | COMPLETED

156 Participants

A Multi-center Outcomes Clinical Study of the PyroTITAN™ HRA Shoulder Implant in Humeral Head Resurfacing

Study Type: OBSERVATIONAL

Last Updated: 2025-12-24

Start Date: 2010-08-31

Completion: 2023-09-30

Conditions

Arthritis

Interventions

DEVICE

Results Available