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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06675812 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Improving Help-seeking Propensity Through a Micro-intervention Targeting Common Concerns Among Individuals With Alcohol Problems: A Randomized Controlled Experiment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-18
Completion: 2025-12-02
Conditions
Alcohol Abuse Harmful Alcohol Use Hazardous Alcohol Use Hazardous Drinking Risky Drinking
Interventions
OTHER
No Results Yet
NCT06671496 | RECRUITING | PHASE3
600 Participants

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-10
Completion: 2027-05-18
Conditions
Psoriatic Arthritis
Interventions
DRUG
No Results Yet
NCT06670040 | RECRUITING | NA
24 Participants

Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-16
Completion: 2026-03-31
Conditions
ASD Autism Spectrum Disorder Autism Depression - Major Depressive Disorder MDD
Interventions
PROCEDURE
No Results Yet
NCT06660394 | RECRUITING | PHASE3
160 Participants

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-25
Completion: 2026-08-21
Conditions
Dravet Syndrome
Interventions
DRUG
No Results Yet
NCT06660121 | RECRUITING
30 Participants

Electrochemotherapy for Desmoid Tumors

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-17
Completion: 2028-08-01
Conditions
Desmoid Fibromatosis
Interventions
PROCEDURE
No Results Yet
NCT06656715 | RECRUITING
100 Participants

Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-16
Completion: 2026-09-01
Conditions
Heart Failure
No Results Yet
NCT06655246 | RECRUITING | PHASE1
157 Participants

A Study of Ziftomenib, an Oral Menin Inhibitor, in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-03-27
Completion: 2027-12-31
Conditions
Gastrointestinal Stromal Tumor (GIST) Gastrointestinal Stromal Tumor (GIST) of the Gastrointestinal Tract Gastrointestinal Stromal Cancer Gastrointestinal Stromal Neoplasm Gastrointestinal Stromal Tumor, Malignant Gastrointestinal Stromal Cell Tumors
Interventions
DRUG
No Results Yet
NCT06640985 | ACTIVE_NOT_RECRUITING | NA
43 Participants

EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-04
Completion: 2026-02-28
Conditions
Wound Healing Diabetic Foot Foot Ulcer, Diabetic Venous Ulcer
Interventions
DEVICE
No Results Yet
NCT06640972 | COMPLETED | PHASE2
68 Participants

Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-27
Completion: 2025-01-04
Conditions
Triglycerides Weight Gain Trajectory Cholesterol, Elevated
Interventions
DRUG
No Results Yet
NCT06635811 | RECRUITING | NA
25 Participants

Circadian Adaptive DBS in Essential Tremor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-01
Completion: 2028-10-31
Conditions
Essential Tremor
Interventions
DEVICE
No Results Yet
NCT06634589 | RECRUITING | PHASE1/PHASE2
80 Participants

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-27
Completion: 2028-12-02
Conditions
B-cell Malignancy Relapsed Cancer Refractory Cancer B-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06627959 | ACTIVE_NOT_RECRUITING | NA
160 Participants

StatSeal vs Figure-of-Eight Suture for Vascular Closure in AF Ablation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-03
Completion: 2025-12-12
Conditions
Atrial Fibrillation (AF) Vascular Access
Interventions
DEVICE
No Results Yet
NCT06619509 | RECRUITING | PHASE2
90 Participants

A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-30
Completion: 2030-12-30
Conditions
Solid Tumours
Interventions
DRUG
No Results Yet
NCT06618872 | RECRUITING | NA
120 Participants

Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-03
Completion: 2027-08-30
Conditions
Dementia Alzheimer Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06615492 | RECRUITING | NA
218 Participants

Routine vs On-demand ECMO for Lung Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-05
Completion: 2028-11-05
Conditions
Respiratory Failure Interstitial Lung Disease (ILD) Pulmonary Fibrosis COPD (Chronic Obstructive Pulmonary Disease)
Interventions
DEVICE
No Results Yet
NCT06613711 | ACTIVE_NOT_RECRUITING | NA
60 Participants

MagDI Italian Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-20
Completion: 2025-06-17
Conditions
Obesity Type 2 Diabetes Mellitus (T2DM) Anastomosis
Interventions
DEVICE
No Results Yet
NCT06610526 | RECRUITING | PHASE4
700 Participants

A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-23
Completion: 2027-05-31
Conditions
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT06609356 | RECRUITING | EARLY_PHASE1
27 Participants

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-03
Completion: 2027-07-31
Conditions
Type 1 Diabetes Mellitus Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY) MODY2 Diabetes Healthy Volunteer
Interventions
PROCEDURE DRUG
No Results Yet
NCT06609044 | COMPLETED
20 Participants

Long-term Impact of NMDAR Encephalitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-16
Completion: 2025-04-04
Conditions
Autoimmune Encephalitis
No Results Yet
NCT06608927 | ACTIVE_NOT_RECRUITING | PHASE3
610 Participants

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-13
Completion: 2030-11-30
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06598579 | NOT_YET_RECRUITING | NA
160 Participants

Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-15
Completion: 2026-08-15
Conditions
Depressive Symptoms Quality of Life
Interventions
BEHAVIORAL
No Results Yet
NCT06585423 | RECRUITING | NA
50 Participants

Tolerability of an Anesthesia-free Tonometer Tip

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-17
Completion: 2026-03-02
Conditions
Glaucoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06577766 | ACTIVE_NOT_RECRUITING | PHASE1
88 Participants

A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2026-03-23
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06576921 | RECRUITING | PHASE2
116 Participants

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-15
Completion: 2026-03-01
Conditions
Stomach Neoplasms Immune Checkpoint Inhibitors
Interventions
DRUG
No Results Yet
NCT06564818 | RECRUITING | PHASE3
220 Participants

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-17
Completion: 2026-08-31
Conditions
Major Depressive Disorder
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06560736 | RECRUITING | NA
30 Participants

Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-01
Completion: 2026-08-31
Conditions
Phenylketonurias
Interventions
BEHAVIORAL
No Results Yet
NCT06557785 | ACTIVE_NOT_RECRUITING | PHASE1
53 Participants

A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2026-01-03
Conditions
HIV Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06554795 | RECRUITING | PHASE1/PHASE2
360 Participants

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2027-02-28
Conditions
Solid Tumor, Adult
Interventions
DRUG
No Results Yet
NCT06545942 | RECRUITING | PHASE1
220 Participants

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2027-05-31
Conditions
Advanced Solid Tumor Metastatic Solid Tumor Prostate Cancer Pancreas Cancer Breast Cancer Ovarian Cancer Homologous Recombination Deficiency
Interventions
DRUG
No Results Yet
NCT06512051 | RECRUITING | PHASE1/PHASE2
248 Participants

A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-30
Completion: 2026-10-31
Conditions
Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06505928 | ACTIVE_NOT_RECRUITING | PHASE2
90 Participants

A Clinical Trial of Hepalatide for Injection in Patients With Chronic Hepatitis D

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-11
Completion: 2026-05-31
Conditions
Hepatitis D
Interventions
DRUG
No Results Yet
NCT06504654 | RECRUITING
60 Participants

Interoception and Eating Behaviors in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-31
Completion: 2026-03-31
Conditions
Obesity, Childhood Eating Behavior
No Results Yet
NCT06503159 | TERMINATED | NA
14 Participants

Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-07
Completion: 2025-09-11
Conditions
Vaping Teens Healthy Volunteers
Interventions
BEHAVIORAL
No Results Yet
NCT06486987 | ACTIVE_NOT_RECRUITING | NA
10 Participants

CHAMP T 2 Pilot of CIMT by Tele-Video

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hemiplegic Cerebral Palsy
Interventions
OTHER
No Results Yet
NCT06483854 | RECRUITING | NA
230907 Participants

Healer-initiated HIV Counseling and Testing Versus Standard of Care in Rural South Africa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2028-05-01
Conditions
Hiv
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06477302 | RECRUITING
281 Participants

Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-23
Completion: 2026-06-23
Conditions
Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06477120 | RECRUITING | NA
60 Participants

Time-restricted Eating Among Pregnant Females With Severe Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-09
Completion: 2026-08-31
Conditions
Obesity, Morbid Time Restricted Eating Pregnancy Weight Gain
Interventions
BEHAVIORAL
No Results Yet
NCT06474546 | RECRUITING | NA
54 Participants

Feasibility of a Diet Intervention for Juvenile Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-07
Completion: 2028-08-31
Conditions
Arthritis, Juvenile Arthritis, Childhood Juvenile Idiopathic Arthritis
Interventions
OTHER
No Results Yet
NCT06473831 | ACTIVE_NOT_RECRUITING | NA
25 Participants

MagDI Australia Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2025-09-04
Conditions
Obesity Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT06469723 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Protocol for Inpatient Nursing Frailty Assessment (INFA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-03
Completion: 2025-12-31
Conditions
Functional Status Frailty
Interventions
OTHER
No Results Yet
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