Clinical Trials Updated in 2025

NCT06717698 | RECRUITING | PHASE2

465 Participants

A Research Study Comparing How Well Different Doses of the Medicine NNC0519-0130 Can Reduce Kidney Damage in People Living With Chronic Kidney Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-02

Completion: 2026-09-01

Conditions

Chronic Kidney Disease

Interventions

DRUG

No Results Yet

NCT06712680 | RECRUITING | PHASE1/PHASE2

115 Participants

A Phase I/II Study of HYP-6589 Monotherapy in Treating Advanced Solid Tumors and in Combination With Tyrosine Kinase Inhibitors in Treating Patients With Advanced NSCLC Positive for Driver Genes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-27

Completion: 2028-04-10

Conditions

Solid Tumor

Interventions

DRUG

No Results Yet

NCT06712290 | WITHDRAWN | NA

0 Participants

Connective Tissue Matrix Compared to Steroid Injections for Rotator Cuff Tendinopathy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-25

Completion: 2025-12-17

Conditions

Rotator Cuff Tendinopathy

Interventions

DRUG

No Results Yet

NCT06703398 | RECRUITING | PHASE2

98 Participants

A Study of GC101 TIL in Advanced Melanoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-20

Completion: 2026-07-10

Conditions

Melanoma

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT06700447 | ACTIVE_NOT_RECRUITING | NA

2163 Participants

Protecting Against HIV Vaccine Misinformation With Adolescent Girls and Young Women in South Africa

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-07-24

Completion: 2026-12-31

Conditions

Misinformation HIV Vaccine

Interventions

BEHAVIORAL

No Results Yet

NCT06690775 | RECRUITING | PHASE2

230 Participants

CATALINA-2: A Clinical Study of TORL-1-23 in Platinum-resistant Ovarian Cancer.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-20

Completion: 2027-10-31

Conditions

Epithelial Ovarian Cancer Primary Peritoneal Fallopian Tube Cancer Endometrioid Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06688370 | TERMINATED

12 Participants

The Performance and Safety of Petit Drill in the French Paediatric Population: a Post-market Clinical Follow-up Study

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-03-14

Completion: 2024-11-07

Conditions

Sore-throat Cough

Interventions

DEVICE

Results Available

NCT06687980 | RECRUITING | PHASE3

136 Participants

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 2)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-25

Completion: 2027-04-12

Conditions

Lichen Simplex Chronicus

Interventions

DRUG

No Results Yet

NCT06687967 | RECRUITING | PHASE3

136 Participants

A Study to Investigate Improvement in Pruritus of Lichen Simplex Chronicus With Dupilumab Injections Compared With Placebo in Male and Female Participants Aged at Least 18 Years (STYLE 1)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-28

Completion: 2027-04-12

Conditions

Lichen Simplex Chronicus

Interventions

DRUG

No Results Yet

NCT06684964 | RECRUITING

40 Participants

RWE,NIS,Prospective Study for the Effectiveness, Tolerability and Adherence of Asciminib in Saudi Arabia. (ASC4REAL)

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-24

Completion: 2026-12-30

Conditions

Chronic Myelogenous Leukemia in Chronic Phase

Interventions

OTHER

No Results Yet

NCT06680557 | COMPLETED | NA

49 Participants

Exercises on Children and Adolescents With Type 1 Diabetes Mellitus (T1DM)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-01

Completion: 2025-08-31

Conditions

Diabetes Mellitus, Type 1

Interventions

BEHAVIORAL

No Results Yet

NCT06680128 | RECRUITING | PHASE1/PHASE2

402 Participants

A Study to Assess the Safety, Reactogenicity, and Immunogenicity of SK Japanese Encephalitis Messenger Ribonucleic Acid (mRNA) Vaccines (GBP560) in Healthy Adults

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-02-24

Completion: 2026-06-26

Conditions

Japanese Encephalitis Virus Disease

Interventions

BIOLOGICAL

No Results Yet

NCT06675812 | ACTIVE_NOT_RECRUITING | NA

200 Participants

Improving Help-seeking Propensity Through a Micro-intervention Targeting Common Concerns Among Individuals With Alcohol Problems: A Randomized Controlled Experiment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-18

Completion: 2025-12-02

Conditions

Alcohol Abuse Harmful Alcohol Use Hazardous Alcohol Use Hazardous Drinking Risky Drinking

Interventions

OTHER

No Results Yet

NCT06671496 | RECRUITING | PHASE3

600 Participants

A Study of Zasocitinib in Adults With Psoriatic Arthritis Who Have or Have Not Been Treated With Biologic Medicines

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-10

Completion: 2027-05-18

Conditions

Psoriatic Arthritis

Interventions

DRUG

No Results Yet

NCT06670040 | RECRUITING | NA

24 Participants

Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-16

Completion: 2026-03-31

Conditions

ASD Autism Spectrum Disorder Autism Depression - Major Depressive Disorder MDD

Interventions

PROCEDURE

No Results Yet

NCT06660394 | RECRUITING | PHASE3

160 Participants

A Phase 3, Placebo-Controlled Study to Investigate LP352 in Children and Adults With Dravet Syndrome (DS)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-25

Completion: 2026-08-21

Conditions

Dravet Syndrome

Interventions

DRUG

No Results Yet

NCT06660121 | RECRUITING

30 Participants

Electrochemotherapy for Desmoid Tumors

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-10-17

Completion: 2028-08-01

Conditions

Desmoid Fibromatosis

Interventions

PROCEDURE

No Results Yet

NCT06656715 | RECRUITING

100 Participants

Symptom Burden and Health Related Quality of Life of Cancer Patients With Concurrent Heart Failure

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-16

Completion: 2026-09-01

Conditions

Heart Failure

No Results Yet

NCT06655246 | RECRUITING | PHASE1

157 Participants

A Study of Ziftomenib, an Oral Menin Inhibitor, in Combination With Imatinib in Patients With Advanced Gastrointestinal Stromal Tumors (GIST)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-03-27

Completion: 2027-12-31

Conditions

Gastrointestinal Stromal Tumor (GIST) Gastrointestinal Stromal Tumor (GIST) of the Gastrointestinal Tract Gastrointestinal Stromal Cancer Gastrointestinal Stromal Neoplasm Gastrointestinal Stromal Tumor, Malignant Gastrointestinal Stromal Cell Tumors

Interventions

DRUG

No Results Yet

NCT06640985 | ACTIVE_NOT_RECRUITING | NA

43 Participants

EDX110 - Efficacy and Safety in the Management of Hard-to-heal Wounds

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-04

Completion: 2026-02-28

Conditions

Wound Healing Diabetic Foot Foot Ulcer, Diabetic Venous Ulcer

Interventions

DEVICE

No Results Yet

NCT06640972 | COMPLETED | PHASE2

68 Participants

Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-27

Completion: 2025-01-04

Conditions

Triglycerides Weight Gain Trajectory Cholesterol, Elevated

Interventions

DRUG

No Results Yet

NCT06636656 | ACTIVE_NOT_RECRUITING | PHASE2

45 Participants

A Study to Test Whether BI 3032950 Helps People With Ulcerative Colitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-11

Completion: 2026-01-19

Conditions

Ulcerative Colitis

Interventions

DRUG

No Results Yet

NCT06635811 | RECRUITING | NA

25 Participants

Circadian Adaptive DBS in Essential Tremor

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-05-01

Completion: 2028-10-31

Conditions

Essential Tremor

Interventions

DEVICE

No Results Yet

NCT06634589 | RECRUITING | PHASE1/PHASE2

80 Participants

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-27

Completion: 2028-12-02

Conditions

B-cell Malignancy Relapsed Cancer Refractory Cancer B-cell Lymphoma

Interventions

DRUG

No Results Yet

NCT06632457 | RECRUITING | PHASE3

1590 Participants

LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-12

Completion: 2029-06-05

Conditions

Metabolic Dysfunction Associated Steatohepatitis

Interventions

DRUG

No Results Yet

NCT06632444 | RECRUITING | PHASE3

1800 Participants

LIVERAGE™: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-10-14

Completion: 2031-12-27

Conditions

Metabolic Dysfunction Associated Steatohepatitis (MASH) Liver Fibrosis

Interventions

DRUG

No Results Yet

NCT06627959 | ACTIVE_NOT_RECRUITING | NA

160 Participants

StatSeal vs Figure-of-Eight Suture for Vascular Closure in AF Ablation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-01-03

Completion: 2025-12-12

Conditions

Atrial Fibrillation (AF) Vascular Access

Interventions

DEVICE

No Results Yet

NCT06619509 | RECRUITING | PHASE2

90 Participants

A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-30

Completion: 2030-12-30

Conditions

Solid Tumours

Interventions

DRUG

No Results Yet

NCT06618872 | RECRUITING | NA

120 Participants

Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-03

Completion: 2027-08-30

Conditions

Dementia Alzheimer Disease

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06615492 | RECRUITING | NA

218 Participants

Routine vs On-demand ECMO for Lung Transplantation

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-11-05

Completion: 2028-11-05

Conditions

Respiratory Failure Interstitial Lung Disease (ILD) Pulmonary Fibrosis COPD (Chronic Obstructive Pulmonary Disease)

Interventions

DEVICE

No Results Yet

NCT06613711 | ACTIVE_NOT_RECRUITING | NA

60 Participants

MagDI Italian Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-20

Completion: 2025-06-17

Conditions

Obesity Type 2 Diabetes Mellitus (T2DM) Anastomosis

Interventions

DEVICE

No Results Yet

NCT06610526 | RECRUITING | PHASE4

700 Participants

A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-08-23

Completion: 2027-05-31

Conditions

Chronic Kidney Disease

Interventions

DRUG

No Results Yet

NCT06609356 | RECRUITING | EARLY_PHASE1

27 Participants

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-07-03

Completion: 2027-07-31

Conditions

Type 1 Diabetes Mellitus Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY) MODY2 Diabetes Healthy Volunteer

Interventions

PROCEDURE DRUG

No Results Yet

NCT06609044 | COMPLETED

20 Participants

Long-term Impact of NMDAR Encephalitis

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-16

Completion: 2025-04-04

Conditions

Autoimmune Encephalitis

No Results Yet

NCT06608927 | ACTIVE_NOT_RECRUITING | PHASE3

610 Participants

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-13

Completion: 2030-11-30

Conditions

Metastatic Pancreatic Ductal Adenocarcinoma

Interventions

DRUG

No Results Yet

NCT06598579 | NOT_YET_RECRUITING | NA

160 Participants

Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2026-02-15

Completion: 2026-08-15

Conditions

Depressive Symptoms Quality of Life

Interventions

BEHAVIORAL

No Results Yet

NCT06585423 | RECRUITING | NA

50 Participants

Tolerability of an Anesthesia-free Tonometer Tip

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-10-17

Completion: 2026-03-02

Conditions

Glaucoma

Interventions

DIAGNOSTIC_TEST

No Results Yet

NCT06584357 | RECRUITING

1200 Participants

Development of a Database to Investigate Digital and Blood-Based Biomarkers and Their Relationship to Tau and Amyloid PET Imaging in Older Participants Who Are Cognitively Normal (CN), Have Mild Cognitive Impairment (MCI), or Have Mild-to-Moderate AD Dementia

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-26

Completion: 2028-07-31

Conditions

Mild Cognitive Impairment Alzheimer's Disease Alzheimer's Disease, Early Onset Memory Loss Memory Disorders Memory Impairment

Interventions

OTHER RADIATION

No Results Yet

NCT06580509 | NOT_YET_RECRUITING | EARLY_PHASE1

12 Participants

TranExamic Atomized for Pediatric Post-Operative Tonsillectomy Hemorrhage: Pilot Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-12-31

Completion: 2027-09-30

Conditions

Hemorrhage, Surgical Tonsillar Bleeding

Interventions

DRUG OTHER

No Results Yet

NCT06577935 | RECRUITING | PHASE2

350 Participants

A Trial Evaluating Efficacy of AGA2118 in PostMenopausal Women wIth Low Bone MasS (ARTEMIS)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-10-31

Completion: 2026-08-31

Conditions

Postmenopausal Osteoporosis

Interventions

DRUG OTHER

No Results Yet