Clinical Trials

Showing trials with last updates posted in 2025.

NCT06640972 | COMPLETED | PHASE2
68 Participants

Effects of RDX-002 on Postprandial Triglycerides in Patients Discontinuing GLP-1 Agonists

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-27
Completion: 2025-01-04
Conditions
Triglycerides Weight Gain Trajectory Cholesterol, Elevated
Interventions
DRUG
No Results Yet
NCT06635811 | RECRUITING | NA
25 Participants

Circadian Adaptive DBS in Essential Tremor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-01
Completion: 2028-10-31
Conditions
Essential Tremor
Interventions
DEVICE
No Results Yet
NCT06634589 | RECRUITING | PHASE1/PHASE2
80 Participants

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-27
Completion: 2028-12-02
Conditions
B-cell Malignancy Relapsed Cancer Refractory Cancer B-cell Lymphoma
Interventions
DRUG
No Results Yet
NCT06627959 | ACTIVE_NOT_RECRUITING | NA
160 Participants

StatSeal vs Figure-of-Eight Suture for Vascular Closure in AF Ablation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-01-03
Completion: 2025-12-12
Conditions
Atrial Fibrillation (AF) Vascular Access
Interventions
DEVICE
No Results Yet
NCT06619509 | RECRUITING | PHASE2
90 Participants

A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-30
Completion: 2030-12-30
Conditions
Solid Tumours
Interventions
DRUG
No Results Yet
NCT06618872 | RECRUITING | NA
120 Participants

Incremental Diagnostic Value of Tau-PET With [18F]RO948 vs Amyloid-PET in Patients With Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-03
Completion: 2027-08-30
Conditions
Dementia Alzheimer Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06615492 | RECRUITING | NA
218 Participants

Routine vs On-demand ECMO for Lung Transplantation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-05
Completion: 2028-11-05
Conditions
Respiratory Failure Interstitial Lung Disease (ILD) Pulmonary Fibrosis COPD (Chronic Obstructive Pulmonary Disease)
Interventions
DEVICE
No Results Yet
NCT06613711 | ACTIVE_NOT_RECRUITING | NA
60 Participants

MagDI Italian Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-20
Completion: 2025-06-17
Conditions
Obesity Type 2 Diabetes Mellitus (T2DM) Anastomosis
Interventions
DEVICE
No Results Yet
NCT06610526 | RECRUITING | PHASE4
700 Participants

A Study of Dapagliflozin in Chinese Adult Patients With Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-23
Completion: 2027-05-31
Conditions
Chronic Kidney Disease
Interventions
DRUG
No Results Yet
NCT06609356 | RECRUITING | EARLY_PHASE1
27 Participants

Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-07-03
Completion: 2027-07-31
Conditions
Type 1 Diabetes Mellitus Glucokinase-Maturity Onset Diabetes of the Young (GCK-MODY) MODY2 Diabetes Healthy Volunteer
Interventions
PROCEDURE DRUG
No Results Yet
NCT06609044 | COMPLETED
20 Participants

Long-term Impact of NMDAR Encephalitis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-16
Completion: 2025-04-04
Conditions
Autoimmune Encephalitis
No Results Yet
NCT06608927 | ACTIVE_NOT_RECRUITING | PHASE3
610 Participants

Study of Quemliclustat and Chemotherapy Versus Placebo and Chemotherapy in Patients With Metastatic Pancreatic Ductal Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-13
Completion: 2030-11-30
Conditions
Metastatic Pancreatic Ductal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT06598579 | NOT_YET_RECRUITING | NA
160 Participants

Evaluation of MBCT Implemented in Vietnamese Buddhist Pagoda

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2026-02-15
Completion: 2026-08-15
Conditions
Depressive Symptoms Quality of Life
Interventions
BEHAVIORAL
No Results Yet
NCT06585423 | RECRUITING | NA
50 Participants

Tolerability of an Anesthesia-free Tonometer Tip

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-17
Completion: 2026-03-02
Conditions
Glaucoma
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06577766 | ACTIVE_NOT_RECRUITING | PHASE1
88 Participants

A Research Study on How NNC0638-0355, a New Medicine, Works in People Living With Overweight or Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2026-03-23
Conditions
Obesity Overweight
Interventions
DRUG
No Results Yet
NCT06576921 | RECRUITING | PHASE2
116 Participants

Efficacy and Safety of Serplulimab Combined With Chemotherapy as Neoadjuvant Treatment for Locally Advanced Gastric Cancer or Adenocarcinoma of Esophagogastric Junction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-15
Completion: 2026-03-01
Conditions
Stomach Neoplasms Immune Checkpoint Inhibitors
Interventions
DRUG
No Results Yet
NCT06564818 | RECRUITING | PHASE3
220 Participants

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-17
Completion: 2026-08-31
Conditions
Major Depressive Disorder
Interventions
DRUG BEHAVIORAL
No Results Yet
NCT06560736 | RECRUITING | NA
30 Participants

Development of Novel Psychological Assessment Tools and Anxiety Intervention for Phenylketonuria

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-01
Completion: 2026-08-31
Conditions
Phenylketonurias
Interventions
BEHAVIORAL
No Results Yet
NCT06557785 | ACTIVE_NOT_RECRUITING | PHASE1
53 Participants

A Clinical Trial to Evaluate the Safety and Immunogenicity of CH505M5 N197D mRNA-gp160 Followed by CH505 TF mRNA-gp160 in Adults in Overall Good Health Without HIV

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2026-01-03
Conditions
HIV Infections
Interventions
BIOLOGICAL
No Results Yet
NCT06554795 | RECRUITING | PHASE1/PHASE2
360 Participants

First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-03
Completion: 2027-02-28
Conditions
Solid Tumor, Adult
Interventions
DRUG
No Results Yet
NCT06545942 | RECRUITING | PHASE1
220 Participants

Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2027-05-31
Conditions
Advanced Solid Tumor Metastatic Solid Tumor Prostate Cancer Pancreas Cancer Breast Cancer Ovarian Cancer Homologous Recombination Deficiency
Interventions
DRUG
No Results Yet
NCT06512051 | RECRUITING | PHASE1/PHASE2
248 Participants

A Trial of SHR-A2102 With Adebrelimab With or Without Other Antitumor Therapy in Advanced or Metastatic Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-07-30
Completion: 2026-10-31
Conditions
Advanced or Metastatic Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06505928 | ACTIVE_NOT_RECRUITING | PHASE2
90 Participants

A Clinical Trial of Hepalatide for Injection in Patients With Chronic Hepatitis D

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-12-11
Completion: 2026-05-31
Conditions
Hepatitis D
Interventions
DRUG
No Results Yet
NCT06504654 | RECRUITING
60 Participants

Interoception and Eating Behaviors in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-10-31
Completion: 2026-03-31
Conditions
Obesity, Childhood Eating Behavior
No Results Yet
NCT06503159 | TERMINATED | NA
14 Participants

Hippocampal Network Changes Following Mindfulness Training in Tobacco Vaping Adolescents in an Open-label, Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-05-07
Completion: 2025-09-11
Conditions
Vaping Teens Healthy Volunteers
Interventions
BEHAVIORAL
No Results Yet
NCT06486987 | ACTIVE_NOT_RECRUITING | NA
10 Participants

CHAMP T 2 Pilot of CIMT by Tele-Video

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hemiplegic Cerebral Palsy
Interventions
OTHER
No Results Yet
NCT06483854 | RECRUITING | NA
230907 Participants

Healer-initiated HIV Counseling and Testing Versus Standard of Care in Rural South Africa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-11-25
Completion: 2028-05-01
Conditions
Hiv
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06477302 | RECRUITING
281 Participants

Scale of Therapeutic Adherence to Respiratory Rahabilitation for Lung Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2023-06-23
Completion: 2026-06-23
Conditions
Lung Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06477120 | RECRUITING | NA
60 Participants

Time-restricted Eating Among Pregnant Females With Severe Obesity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-09-09
Completion: 2026-08-31
Conditions
Obesity, Morbid Time Restricted Eating Pregnancy Weight Gain
Interventions
BEHAVIORAL
No Results Yet
NCT06474546 | RECRUITING | NA
54 Participants

Feasibility of a Diet Intervention for Juvenile Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-04-07
Completion: 2028-08-31
Conditions
Arthritis, Juvenile Arthritis, Childhood Juvenile Idiopathic Arthritis
Interventions
OTHER
No Results Yet
NCT06473831 | ACTIVE_NOT_RECRUITING | NA
25 Participants

MagDI Australia Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-13
Completion: 2025-09-04
Conditions
Obesity Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT06469723 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Protocol for Inpatient Nursing Frailty Assessment (INFA)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-03
Completion: 2025-12-31
Conditions
Functional Status Frailty
Interventions
OTHER
No Results Yet
NCT06468228 | RECRUITING | PHASE3
1280 Participants

A Study to Assess Disease Activity and Safety of Lutikizumab in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-27
Completion: 2026-12-31
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
NCT06467955 | RECRUITING | NA
60 Participants

MagDI Canada Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-10
Completion: 2026-02-28
Conditions
Obesity Type 2 Diabetes
Interventions
DEVICE
No Results Yet
NCT06459973 | RECRUITING | PHASE1/PHASE2
252 Participants

A Clinical Study of YL205 in Patients With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-06-04
Completion: 2027-07-31
Conditions
Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06449001 | RECRUITING | PHASE3
6 Participants

Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2025-08-11
Completion: 2027-05-28
Conditions
Paroxysmal Nocturnal Hemoglobinuria PNH Extravascular Hemolysis
Interventions
DRUG
No Results Yet
NCT06430229 | COMPLETED | NA
110 Participants

Atelectasis Frequency in Different Ventilation Modes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-03-20
Completion: 2024-06-10
Conditions
Lung Ultrasound General Anesthesia Pulmonary Atelectasis Mechanical Ventilation Complication
Interventions
PROCEDURE
No Results Yet
NCT06424340 | RECRUITING | PHASE1/PHASE2
29 Participants

MB-dNPM1-TCR.1 in Relapsed/Refractory AML

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-08-01
Completion: 2028-06-30
Conditions
Leukemia, Myeloid, Acute
Interventions
BIOLOGICAL
No Results Yet
NCT06424327 | RECRUITING
600 Participants

A Registry for People With Lung Cancer

Study Type: OBSERVATIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-15
Completion: 2029-05-15
Conditions
Lung Cancer Lung Cancer Stage I
Interventions
OTHER
No Results Yet
NCT06422689 | ACTIVE_NOT_RECRUITING | PHASE4
1507 Participants

Combination Short-Acting BroNchodilator and Inhaled Corticosteroid Rescue Therapy on Health Outcomes in Routine Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-23
Start Date: 2024-05-10
Completion: 2026-04-29
Conditions
Asthma
Interventions
DRUG
No Results Yet
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