Clinical Trials Updated in 2025

NCT06186765 | RECRUITING | NA

150 Participants

F15 Recharge Free Axonics SNM System Clinical Study

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-12-08

Completion: 2026-03-31

Conditions

Urinary Urge Incontinence (UUI) Urinary Frequency (UF) Fecal Incontinence (FI)

Interventions

DEVICE

No Results Yet

NCT06178952 | RECRUITING | NA

102 Participants

Transcranial Pulse Stimulation (TPS) in Post-COVID-19

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-08

Completion: 2027-01-31

Conditions

Post-COVID-19 Syndrome Fatigue

Interventions

DEVICE

No Results Yet

NCT06161506 | RECRUITING | PHASE2

41 Participants

Surface Electrical Stimulation for Urinary Incontinence in Men Treated for Prostate Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-02-15

Completion: 2027-12-01

Conditions

Urinary Urge Incontinence Stress Urinary Incontinence Prostatic Hyperplasia

Interventions

DEVICE

No Results Yet

NCT06156397 | COMPLETED | NA

45 Participants

The Effect of Technological Based Rehabilitation Practices After Breast Cancer Surgery

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-30

Completion: 2024-01-30

Conditions

Breast Cancer

Interventions

OTHER

No Results Yet

NCT06153810 | COMPLETED | NA

26 Participants

Efficacy of AesyBite Active in Reducing Sleep Bruxism Activity

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-17

Completion: 2025-11-07

Conditions

Sleep Bruxism

Interventions

DEVICE

No Results Yet

NCT06145334 | ACTIVE_NOT_RECRUITING | NA

19 Participants

VOICES Socials for Older Veterans With Depression

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-02

Completion: 2026-01-01

Conditions

Depression Loneliness Isolation

Interventions

BEHAVIORAL

No Results Yet

NCT06143956 | RECRUITING | PHASE2

1217 Participants

A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-17

Completion: 2026-06-30

Conditions

Obesity Overweight

Interventions

DRUG

No Results Yet

NCT06138522 | RECRUITING

65 Participants

Qualitative Study on the Perception of Changes in the Psychotherapy of Traumatized Young People

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-30

Completion: 2028-05-31

Conditions

Post-traumatic Stress Disorder

Interventions

BEHAVIORAL

No Results Yet

NCT06137157 | RECRUITING | PHASE1

12 Participants

Evaluation of Topical ATR12-351 in Adults With Netherton Syndrome

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-06-19

Completion: 2026-06-01

Conditions

Netherton Syndrome

Interventions

DRUG

No Results Yet

NCT06136741 | ACTIVE_NOT_RECRUITING | PHASE2

396 Participants

A Phase 2b Study to Evaluate Rezpegaldesleukin (Rezpeg) in the Treatment of Adult Patients With Moderate-to-Severe Atopic Dermatitis

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-15

Completion: 2025-05-06

Conditions

Moderate to Severe Atopic Dermatitis

Interventions

DRUG

No Results Yet

NCT06133829 | ACTIVE_NOT_RECRUITING | NA

450 Participants

upREACH Perinatal Home Visitation Program

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-22

Completion: 2026-11-30

Conditions

Pregnancy Postpartum

Interventions

BEHAVIORAL

No Results Yet

NCT06125197 | ACTIVE_NOT_RECRUITING | PHASE1

22 Participants

Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-07-23

Completion: 2026-01-30

Conditions

Lung Cancer

Interventions

BIOLOGICAL

No Results Yet

NCT06120881 | RECRUITING | EARLY_PHASE1

20 Participants

Precision Dosing of Metformin in Youth With T2D

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-04-25

Completion: 2026-12-31

Conditions

Type 2 Diabetes

Interventions

DRUG

No Results Yet

NCT06120712 | COMPLETED | PHASE1/PHASE2

18 Participants

A Study of GC101 TIL in Advanced Melanoma (BZ)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-08

Completion: 2024-11-12

Conditions

Tumor Infiltrating Lymphocytes Safety Melanoma Efficacy Adverse Drug Event

Interventions

BIOLOGICAL

No Results Yet

NCT06105957 | RECRUITING | NA

616 Participants

Optimal Digital Weight Loss Treatment for Rural Individuals

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-03

Completion: 2027-02-28

Conditions

Overweight and Obesity

Interventions

BEHAVIORAL

No Results Yet

NCT06101095 | ACTIVE_NOT_RECRUITING | PHASE4

69 Participants

A Study Assessing Esophageal Function and Remodeling With Dupilumab Compared With Placebo for 24 Weeks Followed by 104 Weeks Open Label in Adult Participants With EoE (REMOdeling With Dupilumab in Eosinophilic Esophagitis Long-term Trial)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-29

Completion: 2025-11-05

Conditions

Eosinophilic Oesophagitis

Interventions

DRUG

No Results Yet

NCT06084481 | RECRUITING | PHASE1

285 Participants

Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-09

Completion: 2026-07-31

Conditions

Hepatocellular Carcinoma Pancreatic Ductal Adenocarcinoma Biliary Tract Cancers Esophageal Squamous Cell Carcinoma Triple Negative Breast Cancer Hormone Receptor+/Human Epidermal Growth Factor Receptor 2 Negative Breast Cancer Head and Neck Squamous-Cell Carcinoma Platinum Resistant High Grade Epithelial Ovarian Cancer

Interventions

DRUG

No Results Yet

NCT06078774 | COMPLETED | NA

10 Participants

Redesigning Pediatric Primary Care Obesity Treatment: Virtual House Calls

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-24

Completion: 2024-08-16

Conditions

Obesity, Pediatric

Interventions

BEHAVIORAL

Results Available

NCT06073457 | RECRUITING | NA

35 Participants

Magnetic Gastro-Ileal or Gastro-Jejunal Diversion Study ("MGI/MGJ Study")

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-06

Completion: 2026-03-31

Conditions

Obesity Type 2 Diabetes

Interventions

DEVICE

No Results Yet

NCT06070649 | RECRUITING | PHASE1

63 Participants

The Potential Therapeutic Effects of Psychedelic, N, N-dimethyltryptamine (DMT), on Alcohol Use Disorder (AUD)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-08-04

Completion: 2026-08-01

Conditions

Alcohol Use Disorder (AUD) Alcohol-Related Disorders Alcohol Use

Interventions

DRUG

No Results Yet

NCT06065540 | ACTIVE_NOT_RECRUITING | PHASE3

2734 Participants

A Research Study to See How Well CagriSema Compared to Semaglutide, Cagrilintide and Placebo Lowers Blood Sugar and Body Weight in People With Type 2 Diabetes Treated With Metformin With or Without an SGLT2 Inhibitor

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-09-27

Completion: 2025-11-19

Conditions

Type 2 Diabetes Mellitus

Interventions

DRUG

No Results Yet

NCT06064110 | COMPLETED | NA

185 Participants

Pictou County PEP: A 6-Month, Home-Based, Personal Empowerment Program for Adults With a Chronic Medical Condition Living in Pictou County

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-24

Completion: 2025-05-14

Conditions

Chronic Condition

Interventions

BEHAVIORAL

No Results Yet

NCT06063395 | COMPLETED

30 Participants

Study of the Size of the Operating Fields Depending on the Morphology of the Patients

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2024-05-15

Completion: 2025-12-17

Conditions

Open Surgery on the Abdominal Aorta

Interventions

PROCEDURE

No Results Yet

NCT06058637 | COMPLETED | NA

234 Participants

iSCREEN-study: Online Nurse-assisted Eye-screening in Home Healthcare

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-03-23

Completion: 2025-11-03

Conditions

Eye Diseases

Interventions

DEVICE

No Results Yet

NCT06058520 | RECRUITING | EARLY_PHASE1

16 Participants

Capsule Microbiota Transplant Therapy for Hidradenitis Suppurativa

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-10-01

Completion: 2026-09-01

Conditions

Hidradenitis Suppurativa

Interventions

DRUG

No Results Yet

NCT06050135 | ACTIVE_NOT_RECRUITING | NA

256 Participants

Roadmap to Parenthood: Testing the Efficacy of a Decision Aid and Planning Tool for Family Building After Cancer

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-05-20

Completion: 2027-01-31

Conditions

Quality of Life Parenthood Status

Interventions

OTHER

No Results Yet

NCT06047353 | RECRUITING | NA

48 Participants

Community Health Advocates for Motivating PAP Use in Our Neighborhoods.

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-09-29

Completion: 2027-12-01

Conditions

Obstructive Sleep Apnea

Interventions

BEHAVIORAL DEVICE

No Results Yet

NCT06027242 | RECRUITING | NA

120 Participants

Oral Supplementation of Glutamine on Gastric Cancer Patients After Gastrectomy

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-02-21

Completion: 2026-08-30

Conditions

Gastric Cancer Immunonutrition Gastrostomy

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT06013046 | RECRUITING | NA

108 Participants

Wheelchair User Physical Activity Training Intervention to Enhance Cardiometabolic Health

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-08-10

Completion: 2027-10-01

Conditions

Physical Disability

Interventions

BEHAVIORAL

No Results Yet

NCT06000410 | COMPLETED | PHASE3

594 Participants

A Study to Evaluate the Efficacy of Amniotic Suspension Allograft in Patients With Osteoarthritis of the Knee

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-09-06

Completion: 2025-08-15

Conditions

Knee Osteoarthritis

Interventions

BIOLOGICAL DRUG

No Results Yet

NCT05998408 | RECRUITING | PHASE1/PHASE2

145 Participants

JAK1/2 Inhibitor Ruxolitinib for Relapsed/Refractory Immune Bone Marrow Failure

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-02-20

Completion: 2030-06-03

Conditions

Severe Aplastic Anemia Single Lineage Cytopenias, T-LGL Hypoplastic MDS

Interventions

DRUG

No Results Yet

NCT05996835 | RECRUITING | PHASE2

320 Participants

Phase 2b Study to Investigate the Safety and Efficacy of TIN816 in Sepsis-associated Acute Kidney Injury (CLEAR-AKI)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-18

Completion: 2026-02-02

Conditions

Acute Kidney Injury Due to Sepsis

Interventions

BIOLOGICAL OTHER

No Results Yet

NCT05992480 | RECRUITING | PHASE4

40 Participants

REVIVE (Response to the Ebola Virus Vaccine)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2025-12-01

Completion: 2026-05-31

Conditions

Ebola Virus Disease

Interventions

BIOLOGICAL

No Results Yet

NCT05981547 | ACTIVE_NOT_RECRUITING

400 Participants

Patterns and Glycaemic Endpoints for Diagnosing Gestational Diabetes

Study Type: OBSERVATIONAL

Last Updated: 2025-12-23

Start Date: 2023-11-22

Completion: 2026-06-21

Conditions

Gestational Diabetes

Interventions

DEVICE

No Results Yet

NCT05975073 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2

53 Participants

A Phase 1/2 Study of AMG 193 in Combination With IDE397 in Participants With Advanced Methylthioadenosine Phosphorylase (MTAP)-Null Solid Tumors

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-08-01

Completion: 2026-04-01

Conditions

MTAP-null Non-Small-Cell Lung Cancer MTAP-null Solid Tumors

Interventions

DRUG

No Results Yet

NCT05974631 | RECRUITING | NA

125 Participants

Evaluating Treatments for Suicidal Veterans With PTSD

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-07-08

Completion: 2027-04-30

Conditions

Self-directed Violence Post-traumatic Stress Disorder (PTSD)

Interventions

BEHAVIORAL

No Results Yet

NCT05972694 | ACTIVE_NOT_RECRUITING | NA

20 Participants

Effect of Grapes in Inflammatory Bowel Disease

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-09-16

Completion: 2025-08-01

Conditions

Crohn Disease

Interventions

DIETARY_SUPPLEMENT

No Results Yet

NCT05962229 | RECRUITING | PHASE1

18 Participants

Comparative Pharmacokinetics and Pharmacodynamics of Synthetic Nicotine

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-12-06

Completion: 2026-09-30

Conditions

Nicotine Dependence Nicotine Vaping

Interventions

DRUG

No Results Yet

NCT05960773 | SUSPENDED | PHASE2

9 Participants

Decitabine/Cedazuridine (INQOVI), an Oral DNA Demethylating Agent, in Subjects With BAP1 Cancer Predisposition Syndrome and Subclinical, Early-Stage Mesothelioma

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2024-01-31

Completion: 2026-12-01

Conditions

Mesothelioma Malignant Mesothelioma (MM) Early-stage Mesothelioma Subclinical Mesothelioma BRCA1-Associated Protein-1 (BAP1) Mutations Early-stage BAP1-associated Malignancies

Interventions

DRUG

No Results Yet

NCT05943535 | RECRUITING | PHASE3

698 Participants

Study of the Efficacy and Safety of Inhaled Treprostinil in Subjects With Progressive Pulmonary Fibrosis (TETON-PPF)

Study Type: INTERVENTIONAL

Last Updated: 2025-12-23

Start Date: 2023-10-30

Completion: 2027-11-30

Conditions

Progressive Pulmonary Fibrosis Interstitial Lung Disease

Interventions

DRUG DEVICE

No Results Yet